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00:05 | All right. So, what you're at up here, I think there's |
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00:10 | slides in a row. There might five slides from your previous lecture that |
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00:15 | kind of skipped over. And I when I did this, um probably |
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00:20 | move them in. The slides for all and I moved them together because |
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00:26 | makes sense together. Do that kind makes sense. So if you don't |
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00:29 | them in front of you, don't . I don't think the notes are |
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00:34 | or the the information here is particularly or anything that you have to |
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00:38 | oh no, I've got to find . All right, and what we're |
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00:40 | do, there's a couple of things gonna look at today first, we're |
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00:43 | to just kind of deal with these of dealing with um how signals are |
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00:50 | or magnified and organized. Not but modulated. That's kind of the |
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00:55 | thing they should take like 5, minutes maybe. Then what we're gonna |
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00:58 | is we're gonna then jump in and gonna look at these somatic sensory |
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01:02 | ones that kind of referred to um I gotta remember today's thursday two on |
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01:07 | , and and we're gonna look at they're organized and then we're gonna jump |
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01:11 | the eyes and we're gonna look at structure of the eye and what a |
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01:16 | bit of its organization. And then come back after the weekend. Then |
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01:21 | going to look at the physiology, the I actually processes information. So |
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01:27 | kind of the order in which we're today. So like like I |
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01:30 | the first five slides may seem like did they come from? So, |
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01:37 | of them are going to like the look kind of stuff that you've seen |
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01:41 | . So, our starting point here how do the neurons code signal |
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01:46 | And we've talked about this, we said, look, when you're dealing |
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01:50 | a signal, right, we're producing greater potential up here in the cell |
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01:55 | that if it's strong enough and reaches axon hillock, it's going to produce |
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01:59 | potentials. So, you remember That's that's review. And so that's |
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02:03 | this kind of showing here up This is the stimulus that's being |
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02:07 | So, remember when we're talking about , the bottom line represents off the |
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02:11 | line up here represents represents on And the line that's vertical going up and |
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02:17 | kind of tells you how intense it . So this is smaller than |
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02:21 | which is smaller than that. And this is not very intense. This |
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02:24 | more intensive. There's lots or very . Right? That's how we're looking |
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02:28 | the picture. And so it says , when we have this low |
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02:32 | we don't produce a very strong graded . The greater potential is is really |
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02:38 | of weak. It's not enough to the threshold. So because it doesn't |
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02:41 | threshold, you don't get action potentials the length of the neuron, that's |
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02:45 | what that first picture is showing But over here it's saying, |
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02:48 | all right, so here we're getting little bit more intensity. And so |
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02:52 | going to produce a stronger receptor What is a greater potential? And |
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02:57 | that greater potential is enough to get threshold. Which produces action potentials that |
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03:02 | travel down the length that results in release of a neurotransmitter. Okay, |
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03:07 | far so good. And then lastly , look, but when the intensity |
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03:10 | even greater, what's going to happen we get a greater potential greater potential |
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03:15 | there are great potentials will have a equivalent to or similar to the magnitude |
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03:21 | the stimulus. So that's going to an even greater period of of potential |
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03:29 | above threshold, which results in a frequency of action potentials. Now, |
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03:35 | you're looking at these lines going to like an action potential that I've seen |
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03:38 | , remember when we're looking at an potential is over a graph that was |
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03:42 | milliseconds. And what they were doing there stretching it out. And what |
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03:46 | doing in this picture is they're saying you're recording like say over a |
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03:50 | this is kind of what an action looks like it looks like a line |
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03:53 | us. And so there's this long between action potentials here that look long |
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03:58 | us. But relative to that. we can see that there's more action |
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04:02 | in between there. Right. And the reason we have a full action |
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04:06 | because of what unique feature about an potential starts with an R. And |
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04:11 | ended the period. Refractory period. ? So that allows us to go |
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04:19 | and then back off. Right. the actual potential. And then you |
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04:21 | that period of time where it's kind a rest and then you get another |
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04:24 | . And so what they're saying is you're getting more and more and |
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04:27 | So here's the here's the image. want you to picture picture and need |
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04:30 | picture. A needle picked up the morning still and if I barely touch |
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04:37 | with the needle that's what it's You're not even gonna feel it. |
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04:41 | . But if I come up to and go you know you might like |
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04:45 | you feel it and then imagine me a running start and to handing a |
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04:49 | into your arm as hard as I . Well there you go, that's |
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04:52 | third one. So there's an example how we encode intensity when it comes |
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04:58 | the senses or when we're talking about sensory information. Alright. It's encoded |
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05:05 | the frequency of the action potentials. the greater the stimulus it goes through |
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05:12 | that process. Okay. Greater the or is greater than magnitude. That |
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05:16 | greater magnitude greater potentials which means more above threshold which means more action |
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05:22 | That's what all this stuff is telling . But that's not the only way |
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05:26 | we can encode strength and greatness, ? Because there's a point where you |
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05:31 | produce more action potentials. Mhm. the in a particular region, wherever |
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05:43 | receptors are again, we're kind of about touch but this is kind of |
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05:47 | for other things as well. Is you can imagine that there are multitudes |
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05:52 | receptors. Alright. Would you agree that? Like if I was looking |
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05:56 | my skin, we already said there's of a receptor range, you |
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05:59 | or receptive field but you know, can have really, really small receptive |
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06:04 | right next to each other. And the greater the stimulus, the greater |
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06:08 | that I'm going to start stimulating more more receptors outside of that original |
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06:13 | And that's what this is kind of you. It's like look here is |
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06:16 | range of whatever system we're looking What happens is is that that first |
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06:21 | becomes activated and as it's becoming activated can see now the second one becomes |
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06:27 | because they have an overlap. And then as you keep going up |
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06:32 | the third one does. And so of the reason we can determine or |
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06:36 | or detect uh intensity is because we more and more and more receptors into |
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06:46 | signal that's being sent forward. So can imagine one neuron is doing this |
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06:52 | and then you can imagine two neurons doing this and three neurons. So |
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06:55 | the first neuron as the signal gets and stronger like this. In the |
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07:00 | one it's like this and then the one it's like this. And all |
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07:03 | these signals are being sent forward to into into the central nervous system so |
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07:10 | your perception then or your brain understands signal is becoming greater and greater and |
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07:16 | . So the signal is encoded as by the frequency of the action |
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07:22 | And it's also encoded by the number receptors that have been recruited during that |
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07:29 | . That's number two. All So that's a twofold. That's what |
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07:34 | is basically saying right there. Twofold that we detect intensity right now to |
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07:42 | signals. One of the ways that are modulated before they even get into |
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07:48 | central nervous system is through a process lateral inhibition. All right. And |
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07:54 | the easy way to think about you know, or to demonstrate to |
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07:58 | is get your pen right? And if you look at your pen that |
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08:03 | using right now, you have a end and you have a blunt |
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08:06 | right? If you touch yourself with pokey and and just kind of go |
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08:09 | here, you can feel that it's single point, right? But if |
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08:12 | turn it over that point becomes not single point, it's now a broader |
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08:17 | , right? You kind of see So with lateral inhibition. What I |
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08:23 | you to picture is the pokey Alright? If you take that pokey |
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08:26 | and you look at it when you touch it, you see that's touching |
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08:29 | single point. But as you push stylist end further down, you'll see |
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08:34 | the indentation in your skin becomes right? And so what's happening is |
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08:40 | does your brain know where that actual is? All right. And it |
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08:45 | to do with the intensities that were describing. So at the point of |
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08:50 | that would be point B in our cartoon up here. Alright. And |
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08:55 | we increase the intensity, remember, recruiting outwards from that original point of |
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09:00 | . But the strong stimulus as it's down produces action potentials that are going |
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09:05 | travel along collaterals. So you can here's the pathway pathway for B. |
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09:10 | for a pathway for C. And C. Are just areas outside |
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09:14 | B. And what it's saying is as I'm moving that signal up to |
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09:19 | nervous system here, I have collaterals serve to innovate the pathways on the |
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09:27 | pathways and what they are, they're . They're basically, when I release |
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09:32 | neurotransmitter, they inhibit the the signal this particular neuron is trying to |
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09:39 | And so what happens is is it for an image for your nervous system |
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09:45 | only the middle area is being stimulated it's not receiving the signals from A |
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09:49 | C. In other words, you're telling you to I know you're being |
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09:55 | but you're not as stimulated as I , so don't even bother sending the |
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09:59 | upwards, I'm the important signal. so that signal goes up to the |
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10:03 | , the brain says, oh that's stimulation is taking place. Alright, |
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10:08 | it creates this larger contrast. So is what you're receiving up here, |
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10:15 | ? That's what it would look So here's the greater intensity A and |
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10:19 | lesser intensity, relatively speaking. But it arrives up at the level of |
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10:23 | central nervous system really up at the , what it's basically saying is, |
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10:28 | , here's B. It looks much bigger than it actually was, |
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10:31 | what I've done is I've decreased or the surrounding signals. So I get |
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10:37 | greater contrast and the brain perceives the of something large. Alright now |
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10:45 | you can go back and think about a little stylist that I was showing |
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10:48 | alright, when I poked myself, can see how I get that indentation |
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10:53 | you can kind of see there. when I poked myself this direction, |
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10:57 | kind of this broader structure that's poking exact same area that's being stimulated in |
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11:01 | first place here, it feels thick , it feels pokey, right? |
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11:06 | the reason it feels so pokey, though I'm stimulating the same areas is |
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11:10 | result of lateral inhibition. Hello? . No, that's it, You |
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11:31 | understanding exactly what I'm saying, so just repeat what he said, which |
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11:36 | a repetition of what I said. stimulation in the center of this field |
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11:42 | producing the largest signal. And as result of that, that signal inhibits |
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11:47 | surrounding signals which are also being But they're being they're being downplayed or |
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11:54 | . They're the reason why it's called inhibition because it's outside the central |
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12:01 | And as a result, what you up here, right with the central |
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12:06 | system perceives is not all of that , it's only the one that's the |
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12:12 | point of stimulation because of that All right now, it doesn't just |
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12:17 | in touch. Alright, this is for a lot of systems. All |
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12:22 | , we're gonna be looking a little later at bipolar cells in the |
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12:25 | And that's one of the ways bipolar work basically. One gets turned on |
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12:30 | the other one gets inhibited turned off that's how your eyes can perceive the |
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12:35 | before information ever even gets to the nervous system contrast. And what would |
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12:41 | contrast would be light versus dark. example, in these areas, you |
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12:44 | see the darker areas. So darker look dark, lighter areas look |
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12:49 | And it's a function of this mechanism here called lateral inhibition. All right |
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12:59 | , there's a term that we And this is I probably was a |
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13:04 | that was in the other one. not it's a few slides forward in |
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13:07 | particular section might be right after. might be right before the eye stuff |
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13:13 | this slide because like I said I move things around cause I think they |
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13:16 | better together. All right, so what we said is that when we're |
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13:20 | at receptors, receptors respond to a signal, you can't put light up |
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13:27 | a olfactory receptor and stimulated. every receptor has its own modality. |
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13:33 | . And so what we say has particular stimulus for example. Alright. |
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13:37 | so again by those same rules that just use, you know, the |
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13:42 | has to cause a cell to reached . So there's a greater potential that's |
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13:46 | to be produced. That greater potential referred to as a receptor potential. |
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13:50 | if that greater potential results in reaching than what we've done is we've changed |
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13:56 | modality. We've gone from whatever we're to that action potential and that action |
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14:03 | is what allows the signal or the nervous system to understand what's going |
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14:08 | And so it's the number of action that are being ascent the code that |
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14:14 | the central nervous system to understand one . But two. Because of your |
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14:21 | your detecting a specific signal through a receptor. The central nervous system knows |
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14:26 | I get a signal from this particular , that means it's this type of |
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14:31 | . Alright. So if I'm getting signal from my eye then it knows |
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14:35 | I'm receiving light from this particular region my eye which means I'm seeing light |
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14:42 | just say for example right over okay, if my nose is stimulated |
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14:47 | receptors, a specific receptors get I'm detecting strawberry, How's that? |
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14:53 | not really strawberry, but you get idea. Okay now we've talked about |
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15:02 | and physic adaptation. This picture is and physic, right? But what |
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15:07 | want to point out here is that is something that occurs at the level |
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15:13 | the receptor as well as the level the central nervous system. Alright, |
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15:18 | receptor, if it's constantly bombarded over over and over again, what will |
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15:23 | is it recognizes that it's that it's overstimulated and so what it will do |
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15:30 | it will create a mechanism or use mechanism to prevent overstimulation. One of |
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15:36 | ways that it can do is so it's a cell for example, if |
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15:39 | has lots of receptors, one of things it can do is it can |
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15:42 | the number of receptors. Alright, if I have 100 receptors and I'm |
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15:48 | being overstimulated, like well maybe I need that many receptors, let me |
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15:51 | half of them away. So now have 50 receptors, so to get |
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15:54 | same level of intensity, I have you know, really kind of overstimulate |
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15:59 | cell. All right now what this , it allows us to adapt to |
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16:05 | the particular stimulus actually is. And are different ways of adaptation that we're |
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16:11 | gonna go into right now, but example that is an adaptation that we |
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16:15 | to think about is like going from light area to a dark area. |
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16:20 | , that's not adaptation. That's basically of the ways that our eyes determines |
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16:24 | much how much light is getting into eyes. But an example of adaptation |
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16:30 | be remember we talked about hot spicy and we all like hot spicy food |
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16:35 | for people who like I'm not gonna about it, but it's like I |
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16:38 | eat hotter and hotter and hotter In other words, as if I'm |
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16:43 | eating spicy food. My body adapts this idea of like, oh everything |
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16:47 | have has something spicy in it. , I have reduced the number of |
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16:51 | . And so in order for me stimulate those receptors, I've got to |
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16:55 | even more spicy goodness in my That's kind of a terrible example. |
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17:00 | of sort of makes sense. All , so understand that the systems and |
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17:08 | and adjust themselves through this process of . All right. So I told |
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17:15 | it'd be about five or 10 So how good was I was? |
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17:19 | 17. Mhm. What are you to do? All right. |
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17:24 | now what we're gonna do is we're to deal with these somatic sensory |
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17:27 | So, when you hear the word sensory, remember Samantha's body sensory refers |
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17:31 | basically tactile or touch. So, they're basically saying is where we're receiving |
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17:37 | information from the from our body. right. So, we have uh |
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17:43 | is an ascending pathway, meaning it from our body up to the central |
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17:48 | system. So this is a ferret . This is information going from the |
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17:53 | into the central nervous system. All . We sometimes um we're going to |
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18:00 | it up into one of two ways can think of it in terms of |
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18:04 | from below the neck. If it's below the neck, that means it's |
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18:07 | to use spinal nerves, right? if it's above this point, that |
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18:13 | you're gonna be using cranial nerves. right. So, pretty straightforward. |
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18:18 | right. In terms of how we're this up, there's two major pathways |
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18:24 | names. One is called the dorsal pathway, and it has another name |
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18:29 | we're going to see in just a or the intro lateral pathway. All |
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18:34 | . Now, if you pause and at this for a second, dorsal |
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18:38 | also posterior and the other one is and lateral. Do you see what |
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18:45 | got here? Basically, there's the parts of the white matter and that's |
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18:50 | of the things you need to remember we're dealing with pathways we're dealing with |
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18:53 | tracks or the white matter. do you guys see that? |
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19:00 | So, the dorsal pathway, the column pathway deals primarily with fine touch |
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19:07 | or appropriate reception. Alright, your of your body in space, the |
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19:12 | . Collateral pathways primarily deal with pain or temperature. Now, are they |
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19:18 | to that? No, but that's The primary information. Alright, so |
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19:24 | that means is is the dorsal just to below the neck or just above |
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19:28 | neck? What do you think? , that's good. No, that |
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19:33 | the dorsal pathway has an above the and has a portion that's below the |
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19:36 | . What about entro lateral that just or the other? No. |
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19:42 | it's going to have an above neck below neck portion to it. |
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19:47 | so what our starting point is is to be really? How do we |
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19:52 | these in general? All right. , it doesn't matter which the matter |
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19:56 | pathway. You have? All somatic pathways? I should be careful because |
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20:01 | always an exception to the rule. generally speaking, there are three neurons |
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20:06 | these pathways. Alright, so we're up and we call them 1st, |
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20:10 | and 3rd order. You might read . Primary secondary and tertiary neurons. |
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20:16 | , I even have up their tertiary if you look. But first order |
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20:21 | order third order. If my starting is is in the periphery and my |
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20:26 | point is in the cns which one going to be first order periphery or |
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20:30 | P and s All right. Which going to be 3rd order cns or |
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20:36 | cns. And where do you think second order is going to be between |
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20:41 | two? That makes sense, Okay. So let's see first order |
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20:47 | . The receptor is going to be on the first order neuron. All |
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20:52 | . So, it's either going to closely associated with or it's going to |
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20:55 | a part of like we were describing . Okay. On Tuesday. |
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21:02 | it's job that receptor is to take stimulus, turn it into an action |
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21:06 | and then conduct that signal inward. right. When we described um the |
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21:13 | nerve we talked about information coming in information and sending information that first neuron |
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21:20 | into the spinal cord. Remember, in the spinal cord itself. Body |
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21:25 | located out in that dorsal ganglion. so there that's what that's representing. |
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21:32 | where the dorsal ganglia would be out the periphery. All right. If |
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21:38 | a cranial nerve, that's not where going to be. It's going to |
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21:40 | in a cranial nerve, nuclei. right. So, understand information. |
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21:46 | it's spinal nerve, it's going to in that language. Now, the |
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21:50 | order neuron is going to project to secondary or second order neuron. Second |
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21:56 | neuron is going to be found in central nervous system. All right. |
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22:01 | , you can see here second order we're going to see it's going to |
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22:05 | either up here in the brain stem it's going to be down here in |
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22:10 | spinal cord? All right. And is it going to be in the |
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22:14 | cord, the dorsal or posterior Remember we said when that when that |
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22:19 | comes in? When we looked at gray matter, we said it terminates |
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22:22 | there in that dorsal horn. So is an example of it terminating in |
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22:27 | dorsal horn, right there. But some of them won't. They'll be |
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22:32 | to the brain stem if you're originating you're not a spinal nerve. Look |
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22:36 | you're gonna be a cranial nerve, where that nuclei is going to be |
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22:39 | or nucleus. Now the second order you can see here whether it begins |
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22:45 | the brain stem or if it begins here in the spinal cord is going |
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22:50 | terminate up in the thalamus. All . So the third order neuron always |
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22:55 | in the thalamus. What's the purpose the thalamus sort of sort information? |
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23:01 | does that information need to go? right. So you can see I'm |
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23:05 | somatic sensory information. We know where wants to go. It needs to |
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23:09 | to the somatic sensory cortex but it to go to the thalamus first. |
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23:13 | . Now, at some point it deca state and remember what it |
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23:18 | It means cross. So here we see it's coming in on I guess |
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23:23 | your case it's going to be on left hand side and it's devastating here |
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23:27 | the right hand side here. You see I've entered it on the left |
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23:30 | . I've gone all the way up the brain stem and then I'm devastating |
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23:33 | to the right hand side. so if it's projected to the |
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23:43 | we're dealing with this conscious sensations now are a portion and we're not going |
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23:48 | dive into them, but some of may be going straight to the cerebellum |
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23:51 | you're dealing with appropriate exception. In words, the position of your body |
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23:55 | space. You do not need to aware of where my body is in |
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23:58 | , but your brain needs to know it can tell your brain how to |
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24:02 | about right? So that's why it's sent to the cerebellum. Remember the |
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24:06 | was all about processing information in terms movement, so knowing where everything |
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24:12 | it becomes important, so appropriate. goes to the cerebellum. Finally, |
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24:18 | order neuron cell bodies over here in thalamus. So that's the red |
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24:22 | That's going to go onto this sensory cortex and the parietal lobe. |
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24:28 | one outside the body, into the , two from the spinal cord or |
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24:34 | brain stand up to the thalamus, from the thalamus to the semantics century |
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24:41 | . And that is every one of pathways with the exception of those weird |
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24:44 | that are going to the cerebellum now look at the specific pathways. You'll |
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24:52 | that I break them down. secondary and tertiary or 1st, |
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24:56 | 3rd order. All right. We , the dorsal deals primarily with fine |
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25:02 | and appropriate reception. All right. has another name, remember I |
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25:07 | when you look at the names, names tell you where they're going. |
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25:11 | they are called the dorsal column, meniscal system or pathway. All |
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25:16 | Which is a very, very long . But you're gonna see why |
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25:19 | Alright. So, with regard to , these are my eliminated. All |
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25:23 | . They're traveling up through that dorsal in the white matter of the of |
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25:31 | spinal cord. Alright, so cell bodies are in the dorsal |
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25:37 | They're going to enter into that dorsal column. The physically dorsal physically and |
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25:44 | go into two different structures. If coming from the lower body, you're |
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25:49 | to enter into this region called the is Godzilla's. Now, if you |
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25:54 | when we were looking at the brain , there was a location we named |
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25:59 | the brain stem that wasn't marked in picture. Remember that? It was |
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26:03 | the nucleus Godzillas and had a friend the nucleus status. And this is |
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26:12 | pathway that leads to that nuclei. , so the secular priscilla's meticulous |
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26:22 | They're just tracks that travel up to particular location to those nucleus Godzilla's nucleus |
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26:29 | . Alright, those that's what That's organ of the second neuron. All |
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26:33 | . So, you have to lower it starts with a G. The |
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26:38 | body starts with the sea. Now, here I say, it |
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26:41 | Samantha Topi We've already talked about this basically as fibers enter in what they |
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26:46 | . The ones that are closest to body are nearest to the medial |
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26:50 | The ones that are higher up are lateral. And that's all this is |
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26:53 | saying. And so you can see in the pathway, you know, |
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26:58 | is lower, so it's going to on the medial side. This is |
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27:00 | , It stays lateral. All So the brain stem is where we're |
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27:05 | to see declaration and then you're gonna in from the nucleus. Godzilla's or |
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27:12 | into the medial meniscus that's going to . That's just a pathway that projects |
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27:17 | up to the thalamus. So, you see where the name comes |
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27:20 | It goes up the dorsal column via the nucleus priscilla. Sir kenyatta's then |
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27:26 | the medial limb. Discus up to thalamus from the thalamus to the primary |
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27:31 | cortex. Alright. And what are doing? Fine and touch or appropriate |
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27:36 | ? Where does purpose reception primarily go ? So it's not going up here |
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27:40 | the thalamus. Now, there's a of big names in there and it's |
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27:47 | easier to just map it out. 1231 facility A vesicular kenyatta's facts, |
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27:56 | that just stopping to do this. always gotta stop and pause, |
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28:05 | vesicular kenyatta's vesicular priscilla's. Alright, figure out which one you put that |
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28:12 | one number to begin in nucleus priscilla's kenyatta's via the medial meniscal pathway. |
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28:18 | thalamus, tada magic. What you're find touch some appropriate reception. The |
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28:29 | lateral. All right. So again the pathway is going to be |
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28:34 | All right, they're gonna be in white matter. They're going to be |
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28:37 | the anterior um particularly or the lateral . Where are those? If you |
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28:43 | remember if we're looking So up that would be the dorsal particularly. |
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28:49 | would be the lateral funicular. And here those are the anterior funicular. |
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28:55 | , just basically saying relatively to the matter. Where am I? I'm |
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29:00 | it. I'm in front of I'm behind it and to the side |
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29:02 | it. Alright, so the name tells you Antero lateral, so I'm |
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29:06 | to be on the front of it I'm gonna be on the side of |
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29:09 | system. The other name makes it easier spinal thalamic pathway. Were you |
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29:15 | spinal cord? Where are you going there? Alright again. What are |
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29:20 | conducting? Pain and temperature primarily. still have violated fibers but there might |
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29:25 | some annihilated fibers involved. Okay, it's sending information is not so important |
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29:31 | the information being sent along my element . three chains. 1, |
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29:36 | 3 where the cell bodies located dorsal . Okay, what are we going |
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29:43 | use in terms of the second order . Alright, so we come |
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29:46 | we go in through the dorsal horn I'm in the lateral pathway notice called |
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29:51 | lateral spinal thalamic tract. Alright, here I am I'm going and I'm |
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29:56 | I'm exiting out and I'm now in lateral pathway. Alright, if I'm |
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30:02 | and using anterior pathway, that's the body, so I'm gonna do the |
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30:06 | thing, I'm gonna come in and gonna go out through the anterior side |
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30:09 | I'm gonna stay on the anterior side I'm just going to travel my way |
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30:14 | all the way up to The Thalamus that's where the 3rd order neuron is |
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30:19 | to be. All right. So primary neuron comes into the dorsal |
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30:24 | . Second order neuron deck associates at level of spinal cord travels up and |
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30:30 | terminates on the third order neuron in thalamus. And those are your two |
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30:39 | sensory pathways? Alright, dorsal column the internal lateral pathway. So |
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30:50 | Big words. Yeah. So the of the class, what we're going |
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31:00 | do and and and just to be what we're gonna do is we're now |
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31:05 | with sensory input sensory information. So things we just looked at kind of |
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31:09 | up the sense of touch and pain temperature, all the stuff that we |
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31:14 | about on Tuesday. So we've kind wrap that up and what we're doing |
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31:17 | is we're moving into these areas of special senses? Alright. Special senses |
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31:22 | think are kind of interesting. How my I work? How does my |
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31:24 | work? How does my taste buds ? Why does coffee taste yucky or |
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31:29 | , depending. Right. And so gonna start with the I. And |
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31:33 | we're gonna just kind of work through rest of them and then at the |
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31:36 | of the unit, we're gonna deal the autonomic nervous system and we're going |
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31:40 | deal with the pathways, the motor that come back out again. |
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31:44 | So, we still have pathways to with. But I think doing this |
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31:47 | of makes things a little bit And so, if your eye, |
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31:52 | you're not familiar with your eye, right, that's your eye. It's |
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31:57 | spherical. It's not 100% spherical. right. It's in the orbit of |
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32:02 | skull. So, you know that . It's surrounded by a whole bunch |
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32:05 | fat which you can't see. Thank . Alright. And there's three |
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32:11 | And so you can see up what we've done is we've divided these |
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32:13 | that we have the fibers tunic, the outside layers. Then we have |
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32:16 | kind of middle vascular tunic. So can see this is where the blood |
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32:20 | are gonna be. Right. This kind of the meaty layers. And |
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32:23 | finally, internally we have the which is kind of the the nervous |
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32:28 | layer. Alright, that's the easy to think about it. All |
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32:32 | So the tunic is What covers So we have the square and the |
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32:37 | . We're gonna break all this stuff . The vascular tunic has these different |
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32:40 | the irish. You've probably heard that . But these the silly everybody in |
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32:44 | car ride, you probably have All right. And then the nervous |
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32:47 | , the retina, That's the easy . You've heard that before. Optic |
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32:51 | . You've probably heard that. And it's the retina. In the optic |
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32:53 | . You can see this is nervous . But before we get into the |
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33:00 | and its structures and what they we need to understand what it's |
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33:04 | All right. And I encourage you go onto Wikipedia and look up visible |
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33:09 | and you'll see this picture right This is supposed to be an animated |
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33:13 | . But it doesn't work that way power point. So, it's a |
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33:18 | , flat looking thing. And you've heard probably at some point if you |
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33:22 | physical science way back in 8th grade if you actually have taken physics, |
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33:26 | probably explored visible light a little bit physics to at the college level. |
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33:31 | think in high school, you do the second semester. And what they |
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33:35 | is they talk about light and oh, light is both a particle |
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33:38 | a wave. You've heard that, ? It moves as if it were |
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33:41 | wave and it does. But what's is that the wave is not like |
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33:46 | wave if you take a rope and it, right, the wave is |
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33:50 | different. It actually has to wave that are associated with it. One |
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33:54 | is an electrical field, one that's magnetic field. And if you again |
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33:58 | you go on the Wikipedia and watch video or watch that little gift, |
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34:01 | get mesmerized because these two things are in unison. They don't work |
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34:07 | One is going up while the other is going down. And so it's |
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34:10 | kind of this like I said, can stare at it for a little |
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34:16 | , help you go to sleep at . All right. So, it's |
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34:20 | unique waveform very different than what we the way I like to think about |
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34:27 | and the way I like to think light and photons altogether because they're basically |
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34:33 | of energy. Right? So a photon can stimulate a molecule and pop |
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34:40 | an electron. It's basically it's a and particle. And so these represent |
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34:45 | . And if you look at the of visible light right here, what |
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34:50 | talking about here is strength of In other words, what is the |
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34:55 | of this light which is a representation energy? All right, visible |
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35:01 | Is this small, a portion of entire uh spectrum of electromagnetic radiation? |
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35:09 | right. So, we only see what we what we say what our |
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35:13 | can detect. In other words, eyes are receptors that only detect a |
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35:17 | sliver of electromagnetic radiation. So, have radiation detectors in our heads. |
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35:25 | right. And so that's what you're with. And what they do is |
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35:27 | represent wavelength. And so the wavelength basically just the distance between two wave |
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35:33 | , peaks as you are going in direction. The wavelength increases in terms |
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35:38 | distance. Right? That's wavelength. over here, you have short |
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35:43 | All right. So, you have energy basically there, causing the wave |
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35:46 | go like this up and down. then as you move further and further |
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35:49 | than the wavelengths get weaker and weaker weaker. In terms of energy. |
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35:56 | you get bombarded with gamma rays, happens to you? You become the |
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36:02 | ? That's right glad some people are attention. Right? When you go |
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36:06 | the dentist, do they give you big old giant apron? Put it |
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36:10 | your body, protect your gonads. really what they're there for. Whether |
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36:14 | male or female is there to protect gonads? Got to make sure mutations |
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36:18 | take place in the gonads. we're going to cover you with lead |
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36:21 | the lead can absorb the energy from x rays. Where are your cell |
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|
36:26 | ? Do you guys know? I mean five G? Right, |
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36:31 | scary stuff. Where's five G. you think it's over here? Tell |
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36:35 | when to stop someplace in there. . Five jeeps, microwave. What |
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36:49 | you do with your microwave? You water with it. That's its |
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36:54 | That's an energy wavelength to boil water your food. That's what it |
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36:58 | Is it heats that. That's how get the heating up. All |
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37:01 | So, you can see here, know, our eyes actually detect something |
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37:05 | has greater energy than our phones. right. But there's a lot of |
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37:10 | . There's a lot of wavelength except . Alright, so, we're detecting |
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37:16 | energy with our eyes and it also an amplitude amplitude is the height of |
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37:21 | wavelength, right? Basically, it's height height between this right here. |
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37:26 | the trough. And the top of wave and amplitude just represents intensity. |
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37:33 | , So intensity is like bright light not bright light. Right? |
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37:38 | right now, if you go is this bright light? Yeah, |
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37:41 | kind of walk out there and here it very bright? No. So |
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37:45 | would say is the amplitude, even you're using the same wavelength amplitude can |
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37:51 | . Does that make sense? but like I said, if you |
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37:55 | and watch this thing you're gonna look and go, man, it's even |
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37:57 | complex. Yes. It's more complex I'm just describing. So the purpose |
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38:02 | the eye then is to detect that of energy that photon that is moving |
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38:09 | a specific wavelength and those colors that detect represent different energy forms that are |
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38:15 | detected by the receptors in our Now as an organism. We are |
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38:24 | heavily dependent upon sight and this is a slam against people who have vision |
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38:29 | Alright. But we are an organism basically live by sight. Look at |
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38:34 | our eyes are located on our They're right in the front, the |
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38:39 | of which is we are predators as . We need to see our |
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38:43 | We put there we have bifocal vision we can understand depth and we basically |
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38:48 | our eyes to hunt and to get we want right? So they're right |
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38:54 | in the front as a result we to protect our eyes. And so |
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38:58 | a bunch of structures that do So for example you don't think of |
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39:02 | eyebrows as being protective but they are natural sweatbands for your eyes when you |
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39:10 | water drips down your forehead hits that on your orbital ridge and the water |
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39:15 | moves out to the side and away your eyes for the most part. |
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39:21 | . Not always. I've had water , my eyes just like you have |
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39:25 | right. But it's a pretty good . And look at how your eyebrows |
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39:29 | . Next time you go look in mirror, look at the shape of |
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39:31 | eyebrows. Alright. They are literally little tiny peaks like little tiny roofs |
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39:36 | they're like this and that's why the kind of goes outward. But it |
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39:40 | can go down the nose. Alright spend a lot of time. Ladies |
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39:46 | your lashes look beautiful because one batting eyes at guys is something makes us |
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39:50 | , oh it does right. But are there to prevent large foreign objects |
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39:57 | contacting the surface of the eye, your eyelash and watch what happens you |
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40:04 | close your eyes. All right. mean if you're trying real hard like |
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40:08 | can do that. No, but you let me do it, watch |
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40:11 | happens do you really want me to ? Yeah, mm hmm. Before |
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40:22 | touching someone else's eyelash? That All right. So, I knew |
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40:30 | was gonna happen today. So the is is that the eyelashes there to |
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40:36 | particles in the air and to move away from your eyes. That is |
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|
40:41 | purpose. Okay. Third structure up your eyelids. They have a special |
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40:48 | called the palpa bray, papa bray there to protect your eyes? They |
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40:52 | basically the shutters of your eyes. have one that's up and one that's |
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40:55 | the bottom. So that's the upper the lower. All right. And |
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40:59 | actually are not just little pieces of , There's actually stuff to them. |
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41:04 | muscles inside. Alright. There's Uh if you've ever had uh kind |
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41:09 | that cyst sitting on the end of eyelid that's really just basically a blocked |
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41:14 | , you know? So if you add heat to it if you have |
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41:16 | little baby, this happens all the . You just add a little warm |
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41:19 | and a rag and it will help the skin around it and usually allow |
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41:24 | to squeeze that goo out of So there's two glands. The |
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41:28 | Um I don't think I have the one listed up here, but the |
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41:31 | plans. These are the ones on edge right here where the eyelashes lashes |
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41:36 | located and those basically are there to c. Bum which sits on the |
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41:42 | of the eyelids so that your lack secretion is a fancy word for your |
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41:48 | . Stay on the surface of your . Right? So basically you're like |
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41:53 | like a wax lip, you know there And basically the tears just stay |
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41:59 | the surface and wash over the surface opposed to just dripping everywhere across your |
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42:04 | . All right. I just like use this word because it just sounds |
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|
42:09 | sake or uncle? Your uncle. , the car uncle is that little |
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42:16 | right there. It's where the eye hanging out right in the morning when |
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42:20 | wake up and you're like, I eye boogers and I got to get |
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42:23 | of them. Right? That's your uncle. Right? Oh, there |
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42:29 | a salary gland there. Okay, the conjunctivitis is this structure here. |
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|
42:37 | can see it's on the back of palpa bray. Yeah, folds on |
|
|
42:41 | . That's called the for next. whenever you're structure kind of bends on |
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42:45 | . The point where it bends is the for next. And what it |
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42:47 | it comes and it goes over the of the eye. Except over the |
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42:53 | cornea is going to be in the and then it continues along. So |
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42:56 | all it's all over in the front this and it continues over here. |
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43:00 | can think of like this, it's a shrink wrap uh structure that protects |
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43:05 | surface of the eye. Alright? basically wherever you have the white of |
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43:09 | eye that you can see. That's all right. And then it goes |
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43:14 | and behind the eyelids. So it creates a seal between the external environment |
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|
43:19 | the internal environment around your eye. right. So in other words, |
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43:24 | you poke through that you're now inside body all right, you can see |
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|
43:28 | fat and stuff behind it. So the ocular part is the part |
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43:33 | attached to the skull era. The part is part on the back of |
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|
43:37 | eyelid. Now they're goblet cells goblet cells produce mucus so that's helping |
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|
43:44 | the eye. It's not incredibly And the reason it's not incredibly tight |
|
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43:49 | because if it was then you couldn't your eyes so it's just tight enough |
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43:53 | that it doesn't bunch up. But allows you to keep your eyes moving |
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|
43:57 | , it has lots of nerves in you ever touched your eye kind of |
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44:02 | weird if something touches your eye, be like there's something in my |
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|
44:06 | right? And it's highly vascular Alright. So if you looked at |
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44:10 | eyes and seen it all bloodshot. right. That's in that conjunctivitis. |
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|
44:17 | you've heard of the term conjunctivitis, an infection of that surface structure and |
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|
44:24 | causes your eyes turn of red. right. Key thing here it doesn't |
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44:30 | the cornea. The cornea is So you can think of the cornea |
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44:35 | the the the the clear portion through light is gonna be passing through. |
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44:41 | so you can think of the cornea kind of being the safe space and |
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44:44 | it's kind of like a skirt that from the cornea up and around over |
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44:49 | back of the eyelids. So all things are protecting physically protecting. But |
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|
44:56 | way that we protect as through the ball fluids. Orla Kimmel's secretions. |
|
|
45:01 | right. This is a fancy word tears. There's all sorts of stuff |
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|
45:04 | here. Alright. The key one want to point out here is life |
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|
45:09 | licenses. I'm is one of your natural antibacterial enzymes. All right. |
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|
45:17 | you can imagine it's being in your because this is now wet warm |
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|
45:22 | What wants to live in wet warm bacteria. It's also a place where |
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|
45:27 | produce a lot of I. A. I. G. |
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|
45:30 | Is a antibody that your body is generic antibody that your body produces to |
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|
45:35 | infection. And so your tears have lot of I. G. And |
|
|
45:38 | lot of his life's assignment. All . But you're lacma gland sits on |
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|
45:43 | outside over here. Now when you up where your tears fall primarily kind |
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|
45:49 | over here. Right So what you see here is kind of the general |
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|
45:53 | . And it's because the lack formal through which tears are removed from the |
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|
45:59 | of the eye are found near the Ocurre uncle. Okay so lack of |
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|
46:08 | glands out here on the outer It's constantly producing fluid. These lacquer |
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|
46:13 | fluids at a kind of a constant . That fluid is being pushed over |
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|
46:18 | surface of the eye has all this stuff in it to make sure that |
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|
46:23 | washing debris and particles and bacteria and things killing it off and and removing |
|
|
46:29 | . And then what you have is have these little tiny structures called the |
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|
46:34 | to basically little tiny holes. So have one on the bottom. You |
|
|
46:38 | actually go and see these. These these are not microscopic. You can |
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|
46:41 | look in the mirror and just kind looking and you can see they're sitting |
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|
46:44 | there on the bottom one on the and there's a little tiny canal called |
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|
46:48 | curriculum that then connects to the lack ball sack which is part of the |
|
|
46:52 | lacquer Donald duck. And so you see the flow of tears would be |
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|
46:56 | through the puncture through the through the down through the lateral stack and out |
|
|
47:01 | the nasal cavity. Now to help visualize this, think about when you |
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|
47:07 | right? What happens right? Because you're crying you're producing more legible |
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|
47:17 | a lot of it, you're producing much that it just flows out over |
|
|
47:21 | edges of your eyes. But you're pushing it down and through the pump |
|
|
47:26 | through the curriculum into the lacquer mail and down through the lateral duck. |
|
|
47:30 | it goes into your nasal cavity. you just have extra water in your |
|
|
47:33 | cavity dripping around. And boy we when things are dripping in our nasal |
|
|
47:37 | don't we? That's when you get so you can kind of see the |
|
|
47:44 | . So this is another way the protects itself. There are a series |
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|
47:50 | external muscles called the extrinsic eye muscles memorize the names. But you can |
|
|
47:56 | the rectus means up and down. one on top, one on bottom |
|
|
48:00 | , that side to side or not to side, it's kind of at |
|
|
48:03 | angle and then here you can see rectus and that's gonna be lateral |
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|
48:09 | Alright I'm not gonna ask you the of these. Please do not memorize |
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|
48:12 | . But my goal here is to you is that you are capable of |
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|
48:17 | your eyes because we have muscles attached the surface of the eye, |
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|
48:23 | If you look forward and then just put your eyes over there |
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|
48:27 | look at that person to left. their trouble. All right. Now |
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|
48:31 | at the person at the right there trouble But don't let them know that |
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|
48:34 | looking at him, right? I know what you're doing. You're |
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|
48:38 | rolling your eyes at me, See that's because of those muscles right |
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48:45 | . These are attached to the skull . The white of your Yeah, |
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48:50 | wonder. Oh, mm hmm. , so let me go back |
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48:57 | So, whenever you're talking about what happens is you're squeezing the |
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49:01 | right? So any fluid on the of your eye has to go |
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49:05 | And if you have too much and trying to push it towards the punk |
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49:10 | then it's just gonna go wherever it , right. It also happens when |
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49:14 | watch really, really sappy commercials, always asked why are you crying during |
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49:20 | commercial? Because I have emotions You'll understand when you get older. |
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49:30 | sorry. All right. So, said there's three layers. We have |
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49:34 | tunic. We have the Alright, tunic consists of the square in the |
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49:39 | . Alright, the square, that's white of your eye. The |
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49:42 | that's the clear stuff right in the , right? And you can kinda |
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49:45 | go in the mirror and take a at it and you'll see Oh |
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49:47 | I can see got this kind of bump on the surface of my eye |
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49:52 | corny and so everything else back That's clara. The school era is |
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49:56 | with the dura matter. So you're matter basically is what forms That's clara |
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50:03 | of neat. All right now we're gonna go in the development. I |
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50:07 | even know if your chapter does but what's interesting is how the I actually |
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50:11 | . It's like a structure that develops the inside out. It basically kind |
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50:15 | like goes out and then pops out like this. So it makes sense |
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50:21 | this is kind of why that would um um Dura matter. Alright. |
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50:27 | what is what his purpose is clear ? I shape. That's why you |
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50:30 | a round or spherical. I it your eye. It's really really |
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50:34 | You know? Just like the door tough and it serves as a point |
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50:37 | attachment for those extrinsic muscles. All . So when you think whites of |
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50:42 | eyes, that's the square that I see. But that goes all the |
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50:45 | around the eye. The cornea is we're kind of interested in. Its |
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50:51 | tissue. It is not dead Alright. It's just happens to be |
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50:55 | vascular Alright. So it gets its nutrients from um a little bit from |
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51:01 | tears but not so much. It's from the fluid that sits behind the |
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51:06 | . So you can see there's this space but this is an epithelium very |
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51:11 | alive. Alright, transparent. Its is to allow for light to pass |
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51:16 | the eye. Are receptors for light gonna be located here in the retina |
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51:21 | we'll get to that in a little . All right. The other thing |
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51:24 | it does because of its structure and it's just a different material is that |
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51:29 | light hits it and it's opaque or opaque, it's translucent or transparent. |
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51:34 | translucent transparent, light will hit it it will bend. Alright. That's |
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51:39 | refraction. So the first thing that cornea is doing is it's bending |
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51:44 | And what we're trying to do, trying to bend light so it reaches |
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51:47 | very specific point in the back of eye. When we get to the |
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51:52 | tunic, there are three parts to . Alright, corduroy tell your body |
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51:57 | , iris is what you're most familiar but let's just kind of walk through |
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52:01 | core. Oid you can see is the way around the eye. |
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52:04 | It's basically the vascular layer. This where the blood vessels are. All |
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52:08 | . So you can think of this as being kind of connective tissue that |
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52:13 | and then what we're doing is we're the vasculature underneath that protective layer and |
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52:18 | is what's providing the nutrients to the that are in the new neural layer |
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52:22 | the retina as well as the nutrients the cells that are in this in |
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52:26 | uh fibrous tunic outside. So kind the meat of the sandwich as it |
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52:33 | . All right. And so as come around, you can see we've |
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52:36 | it's better shown right up here we this large structure that formed from the |
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52:42 | . It's called the silly everybody. everybody has a couple of things to |
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52:46 | has muscles and has these processes. processes are just kind of out |
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52:51 | What they do is they produce what called the acquis humor. The humor |
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52:55 | is released and it comes out of space. We're gonna learn about this |
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52:59 | the second and then it kind of outward, fills in the space behind |
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53:03 | cornea and then ultimately empties out in way. So this is where the |
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53:09 | of the cornea are going to get nutrients is from the humor. We'll |
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53:14 | back to it a second. Look the flow. We also have the |
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53:18 | muscles ancillary muscles. There's a type smooth muscle that this is, what |
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53:23 | stuff represents is distinct from the iris the purpose of these, as you |
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53:28 | see they're attached to these ligaments. ligaments are attached to the lens. |
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53:34 | when the muscles contract, they pull the ligaments. And when you pull |
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53:38 | the ligaments, you pull on the and you change the shape of the |
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53:43 | . Alright, so this is what's to allow for what we call |
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53:48 | Being able to see far or Okay. So the celery muscles found |
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53:54 | the silly everybody play a role in . Again, that's something we're going |
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53:59 | talk about in just a minute. last structure is the iris. And |
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54:03 | , this is a bunch of smooth . It's actually interesting. It's a |
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54:07 | that has pigment in it, you ? So when you look at somebody |
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54:10 | say, oh you have such beautiful , right? What you're looking at |
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54:14 | a muscle that has pigment embedded in . And there's actually two different groups |
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54:18 | them. Alright. And what these is when they contract and relax that |
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54:22 | changing the size of the hole through light passes into the eye. |
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54:30 | So the iris is allowing not The the iris allows the amount of |
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54:37 | in the lens which we're going to with in a bit, is what |
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54:40 | with focus. All right. So think yeah, we're going a little |
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54:48 | deeper into this. All right. , there's two muscles there were sphincter |
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54:53 | . We have a dilator muscle. even tell you where they're located their |
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54:56 | of the pupil. So, when look at somebody, how many guys |
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55:01 | had an eye exam? I I can look around and see the |
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55:03 | who wore glasses, but those aren't glasses. Have you ever had eye |
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55:07 | . Alright, what do they Is they take this big old |
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55:10 | right? And they say look forward , they dilate your eyes. So |
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55:13 | muscles don't work, right? So you're this and then what they do |
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55:16 | they shine a light into your eye your pupil. Now when you look |
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55:20 | somebody you see that little black circle actually you looking into their eye, |
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55:26 | just can't see anything in there. like looking into a dark closet because |
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55:31 | your deep dark secrets are in there it makes it all dark. No |
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55:35 | because light is not reflected back at . And so it's dark when you |
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55:40 | at a pupil it's dark because the that's going in never comes back |
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55:45 | Okay. So how do we open close the whole what we're doing is |
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55:51 | changing the size of these two The sphincter muscle is a circular |
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55:57 | Alright? It's p parasympathetic, innovated its contract. I'll. So what |
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56:01 | does is when it contracts it makes hole smaller, what makes a little |
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56:08 | less light goes in. So when bright, this is the one that's |
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56:12 | to be contracting this one's gonna be during that period of time. Now |
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56:18 | there's very little light you want to able to see you need to get |
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56:22 | light into the eye. And so you're gonna do is you want |
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56:25 | So these muscles contract these relaxed, is sympathetic in nature. And what |
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56:30 | is is these are radial in And so what they do when they |
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56:34 | they pull the relaxing circular muscle And so now you have a bigger |
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56:39 | through which light passes. It's still in there because light doesn't escape. |
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56:45 | right. But this is how we how much light is going in and |
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56:50 | . So right now, if you at somebody you can see in |
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56:53 | it's a little bit darker. So have your eyes are a little bit |
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56:56 | dilated. Go outside for like 10 and go look at someone's eyes and |
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57:00 | pupils are like these little itsy bitsy tiny dots, right? Because of |
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57:05 | amount of light that's available. the lens. So, if the |
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57:12 | determines the amount of light going in out of the pupil. Or that |
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57:16 | hole is called the pupil. So the pupil just represents the whole |
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57:22 | , so the lens adjust the size the hole and then that light going |
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57:26 | the pupil. The first thing that's to come into contact with as a |
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57:30 | is the lens. Remember we said lens plays a role in focusing |
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57:34 | All right. And so it's the , how we're gonna focus. So |
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57:38 | what I said we want to get light that's coming into our eyes focused |
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57:42 | here at this little tiny spot at back of our I that doesn't mean |
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57:45 | the only spot that has receptors that's we want the light focused. All |
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57:49 | . And so what we're gonna do we're gonna change the shape of this |
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57:52 | depending upon when we're looking now. is kind of a concept that's a |
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57:56 | bit wonky to understand. So, want you to think about these muscles |
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58:00 | wrapped around a circle. All And so when that muscle contracts, |
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58:05 | it's gonna do is remember it's contracting from the lens itself and it's pulling |
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58:12 | the ligaments, right? When it on the ligaments, it makes the |
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58:16 | thinner. And what that does is when you I'm doing this wrong. |
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58:22 | , I did it wrong. I it backwards time out. Mm. |
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58:26 | hate when I do that when it what it does, it contracts |
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58:32 | Doesn't contract backwards, it contracts And so when it contracts forward, |
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58:38 | happening is it's not actually pulling on ligament anymore. So, normally, |
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58:43 | you think about is when you think a muscle contracting, it can pulls |
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58:46 | a ligament making the ligament or tendon , right? Or the ligament |
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58:51 | And that's not what's going on It's the opposite. So when the |
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58:55 | are going around this round structure, it contracts it contracts this way and |
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58:58 | loosens the ligament. And when you the ligament, you're no longer pulling |
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59:02 | the lens. The lens relaxes and fact. And that allows you to |
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59:07 | things near which is like they're trying show you the watch. All |
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59:10 | So look down at your device or piece of paper in front of |
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59:14 | That would be your muscle being Okay? Now, when your muscle |
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59:22 | right, it falls backwards away from lens and when it falls away from |
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59:26 | lens it pulls on the ligaments. the ligament really really tight, which |
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59:30 | the lens pulled and it gets really thin. And this is your |
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59:35 | view now. How do I remember ? So you saw how I kind |
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59:38 | like, oh wait a second. got it all backwards. How do |
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59:40 | remember this? Think about what happens you're tired? Do you have real |
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59:48 | look when you're tired now, you of get that three mile stare |
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59:52 | don't you? So you can think when my muscles relaxed and I'm |
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59:57 | my lens is getting really tight and why I have that long stare. |
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60:03 | my farsightedness. And you can do really is that people are back. |
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60:07 | easier like the interesting look up, can see how quickly you can accommodate |
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60:12 | really interesting. And this is not in accommodation. Your eyes actually scans |
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60:17 | about 30 times per second. So actually when you look at something you |
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60:22 | just kind of look at it. like You do that about 30,000 times |
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60:26 | second, which is pretty impressive how information you're inputting into your eyes. |
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60:32 | accommodation is simply the process of changing lens from near sighted view too far |
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60:39 | view and it's simply the contraction of muscles. When I'm working hard. |
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60:45 | have to think about what I'm looking the rights and here I am nearsighted |
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60:49 | my muscles are relaxed. That's my . Easy way to remember that. |
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60:58 | , I deal with the question of real quick. Just simply put refraction |
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61:02 | the bending of light when light hits different substance, the light travels through |
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61:07 | at a different speed. All And so what happens is when that |
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61:11 | it changes the speed of light so moves or bends as a result. |
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61:16 | I love the picture. And you you've you've seen that. It's like |
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61:19 | looking at your drink and you see straw and you're like kind of that |
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61:23 | . So this is what is going with your eyes. Light hits these |
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61:27 | transparent structures. They're going to be Now the shape of a lens matters |
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61:33 | if you have a concave lens. ? So the concave lenses, one |
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61:37 | the right, right, that's going cause light to bend away from the |
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61:41 | point, you know? But we a lens that is convex and as |
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61:46 | can see it bends towards the focal . And so I've been pointing out |
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61:50 | focal point over and over on your . So what we have is we |
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61:53 | structure that is trying to bend the towards this focal point in the back |
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61:58 | your eye. Alright Called the So if you think about the |
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62:05 | the eye, you have a you have fluid right filled with Aquarius |
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62:11 | . You have a lens, And then you have another cavity filled |
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62:15 | another liquid. And so each of bend the eye or bend the light |
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62:20 | a little bit to get to that . So the two cavities of the |
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62:26 | . Alright, We have the anterior . We have the posterior cavity. |
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62:30 | just put ourselves in perspective because he the lens. This would be the |
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62:34 | everybody. Alright, so this is the celery muscle is, This is |
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62:39 | we're producing the uh acquis humor and flowing out above the lens and out |
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62:47 | around the iris and then it's emptying in a structure that's located within the |
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62:53 | itself. I don't know. I listed up here. I don't think |
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62:56 | do. All right, but it's best name ever. So, we |
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63:00 | have to note for the test, it's just one of those trivial pursuit |
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63:04 | the way that acquires humor leaves the to a structure called the canal of |
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63:10 | named after somebody I had a hard growing up. I think Slim isn't |
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63:18 | awesome. So the canal of Not the list of there. |
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63:23 | Anyway, you can see we have chambers in the anterior. So here's |
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63:27 | anterior chamber that sits right behind the cornea, just in front of the |
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63:33 | posterior chamber is right behind the just in front of the lens in |
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63:37 | posterior cavity. This is where we're to find vitreous humor. Vitreous humor |
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63:43 | more of a gel. You don't a lot of it new. So |
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63:47 | always kind of making a quick That's why it's flowing when it, |
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63:51 | it gets, when you get proteins in the aqueous humor, That's when |
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63:56 | um it kind of gets gummed up it stops flowing out through the canal |
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63:59 | slim. And that's the, so happens when my brain turns off cataracts |
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64:13 | was looking for? That's a cataract is that kind of gumming up and |
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64:19 | proteins accumulating and becoming more opaque. vitreous humor, it's just kind |
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64:25 | is what it is and it just of sits there, it helps to |
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64:28 | the shape of the eye so that kind of creates this positive pressure outward |
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64:33 | of create that rounded nous or that nous. Um it's still transparent so |
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64:38 | allows I like to be transferred to through it. Have you ever noticed |
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64:42 | little tiny floaties in your eyes when looking at stuff like something like it's |
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64:46 | hard right now, but if you're at a white piece of paper, |
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64:48 | like, oh yeah, and you of try to focus on and it |
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64:50 | of goes up and you keep following . So those are basically um dead |
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64:56 | that are actually sitting in the vitreous . And so what's happening is light |
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65:00 | hitting it. And so you're detecting the light refracting or bouncing off one |
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65:07 | these structures. And that's why you that little tiny floating, they're just |
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65:16 | , look this is just showing you different refraction, right? So what |
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65:21 | light gets bent, bent, bent it comes and as you're bending |
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65:25 | what you're doing is you're moving it the phobia centralist. We haven't talked |
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65:32 | the retina yet, we're about to there. But all structures within the |
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65:37 | , there are a bunch of light . But where we want light focus |
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65:43 | directly behind the lens. This is our greatest acuity is whenever we see |
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65:50 | , notice what we do is we our head or turn our eyes to |
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65:53 | in on it because it gives us greatest security in terms of what we're |
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65:58 | at. So if I'm looking I can see all the way out |
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66:01 | , this is my peripheral vision, can see my fingers wiggling, |
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66:05 | Everyone's a little bit different. You play that game right, You |
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66:09 | But out over here things aren't quite clear, I can kind of detect |
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66:13 | there are people out here, but I see movement, what do I |
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66:16 | is I turn my head and my right? Because that's where my greatest |
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66:21 | . So, that's what we're trying do is we're trying to send light |
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66:25 | that phobia central is because that's where security is gonna be. So, |
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66:30 | leads us to that last structure of retina. All right. Outer tunic |
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66:35 | middle layer vascular also have some muscles it. Help us to focus |
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66:40 | And finally what we're doing is we're light and we're sending it to this |
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66:44 | here. So, I want you envision what we're looking at. |
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66:48 | here light is coming through the cornea the lens and is moving back here |
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66:52 | a phobia centralist. So, we're to show you here. Here's the |
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66:56 | coming into the retina. So there's be layers and layers of cells. |
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67:01 | this, right here is the last cell on the retina, and here's |
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67:05 | cornea. Our receptor cells are going be right here. All right, |
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67:12 | , light passes through cells to get the receptor cells. So, our |
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67:19 | layers, the first layer is a layer. All right, This is |
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67:24 | outermost layer. So, this is one nearest asteroid. Alright. Called |
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67:29 | pigment epithelium. Alright, It's a layer where you have pigments. When |
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67:34 | hits a pigment, what does that do? It absorbs the light. |
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67:38 | , when you look into somebody's what do you see the darkness of |
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67:42 | souls. Right? No, that's it. You don't see anything because |
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67:46 | light is bouncing back out. It's absorbed by this pigmented layer. Now |
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67:50 | is valuable because you don't want light around because you're receptor cells are basically |
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67:56 | this cell right here is detecting light a specific location. And so if |
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68:01 | is bouncing around the inside of your it's telling your brain light is being |
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68:04 | from that particular location over there, example. Right? So if it |
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68:09 | from over here and bounced around and hit that your brain wouldn't know what |
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68:13 | do with that light. So the epithelium absorbs light so that the neural |
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68:19 | the receptor cells can detect light from specific location. The other thing that |
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68:26 | provides vitamin A, vitamin A. going to see in just a little |
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68:30 | vitamin A. Is this kind of um long chain structure with these ring |
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68:35 | structures at the end. If you vitamin A directly in half, you |
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68:39 | up with this molecule called retinol Not O. L. A. |
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68:44 | . Retinol is going to be important terms of detecting light. So it |
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68:51 | the molecule that is like receiving. what vitamin A. Is the neural |
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68:56 | . There's all these different layers. you can see we have a flood |
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68:59 | pigment later we have these other layers are along these neurons and what they |
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69:04 | is they help to transducers that light into a signal and they actually pre |
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69:10 | that signal along the way. this is the layer that's gonna be |
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69:14 | and we're gonna be processing information before even gets sent up through the optic |
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69:19 | to the visual cortex. So, are these layers? All right. |
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69:25 | gonna work our way from the retinal epithelium. So, there's a pigmented |
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69:29 | . All this stuff is a neural . We start here with photo receptor |
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69:33 | . Because well, they're the most there. What the text like it |
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69:38 | in the name photo receptor light Alright, there are two types of |
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69:44 | and cones. Their job is to the light energy into that signal that's |
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69:49 | ultimately be sent up to the All right now they generate because these |
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69:55 | are so small, they don't generate potentials. They generate graded potentials. |
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69:59 | graded potentials are strong enough to produce chemical message that's going to be sent |
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70:05 | . The next layer of cells are the bipolar cells called bipolar cells. |
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70:09 | they are literally bipolar cells. Here's cell body. There is one |
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70:13 | There's the other side, bipolar. , very, very original name. |
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70:18 | right. Now, what we have is we're going to see that the |
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70:22 | of cells are going to be decreasing we move towards the brain. I'm |
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70:26 | make up a number let's say we a million photo receptor cells. The |
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70:30 | of bipolar cells is, for 100,000. Alright. So, we're |
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70:35 | the number of cells. So what doing is we're going to start seeing |
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70:39 | towards the brain And then what we're do is remove the gate land sales |
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70:43 | even fewer. So again if it a million might be 100,000, might |
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70:47 | 10,000. Just making up numbers. . So there's fewer cells. Their |
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70:52 | is to take information from multiple receptor and help to um uh process that |
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71:01 | so that the brain can perceive what actually getting. So it modulates the |
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71:06 | that's being received at the level of receptor. These two also generate graded |
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71:13 | . And what they're doing is they're onto the third level of cells, |
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71:15 | ganglion cells that's yellow ones. so these are the tertiary cell that's |
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71:21 | to be sent on into the nervous . Alright. And what they do |
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71:25 | they actually produce action potentials because they a further distance, the axons of |
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71:33 | ganglion cells converge and form the optic . Alright so the optic nerve is |
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71:39 | to be the one that travels onto thalamus. There are two other layers |
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71:44 | cells we see right here we have horizontal cell and over here we have |
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71:47 | endocrine cells. So you can see horizontal cell sits kind of between the |
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71:51 | receptor and the bipolar cell, they modulate signals. Alright. So not |
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71:56 | are you getting modulation because of convergence the horizontal cells and the immigrant cells |
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72:01 | saying, you know what? I this information needs to be processed even |
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72:06 | . And so it helps helps to how that signal is moving forward. |
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72:10 | , so they integrate information. So horizontal between the photo receptors and the |
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72:16 | cells are between the bipolar and ganglion . So even before light information leaves |
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72:23 | i it's already been processed kind of . one example would be contrast, |
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72:33 | versus dark. Right? You look this up here and you're going that's |
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72:37 | versus that down there, that's But this looks a lot darker to |
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72:41 | than it actually is because your brain that's light, that's dark. I |
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72:45 | to create that contrast. So the better understands light versus dark here. |
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72:51 | just an example of one of the that it does. You ever seen |
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72:57 | optical illusions of like the checkerboard, black and the white and then it's |
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73:01 | you know, it's like over here which color is the same. It's |
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73:04 | they have some gray and you're like , well this gray over here is |
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73:08 | obviously great because there's a shadow but like no it's actually the same color |
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73:11 | the black. That would be an of it being modulated. I used |
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73:15 | show a whole bunch of optical illusions here just to show you what they're |
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73:19 | brain is doing, your book talks this and I just wanted to mention |
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73:26 | . Alright. You may get a on this just because it's interesting. |
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73:30 | don't know. I'm internalize it, guess. Alright, so we have |
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73:36 | are called photosensitive ganglion cells. All . So, we have the photo |
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73:41 | cells. We have bipolar cells. have ganglion cells. Alright, information |
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73:45 | from here this direction and onto the nervous system. The photosensitive ganglion cells |
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73:50 | in this category of cells over That that that third group of |
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73:55 | he says the name ganglion cells, they're photosensitive, meaning they actually respond |
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74:02 | light. All right. And what photo sets of ganglion cells do is |
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74:08 | help your internal circadian clock. It tells your eyes. They respond specifically |
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74:15 | blue light and they will tell your whether or not light is present or |
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74:20 | brain whether or not light is You guys have a hard time going |
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74:26 | sleep when you've been on your phones a long time. I don't |
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74:30 | you're a liar. I mean, can go on and see this like |
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74:38 | absorbent uh shields and stuff for your your computers and stuff because the blue |
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74:44 | stimulates this and it mucks with your rhythm. It's one of the reasons |
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74:48 | we have such a hard time sleeping because we have all these false blue |
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74:53 | that we put right into our brains brain cell. It's the middle of |
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74:57 | day. Middle of the day. of the day. All right. |
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75:02 | also helps to regulate pupil size, size, pupil size. It also |
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75:06 | to regulate the amount of melatonin. you can already see circadian rhythm. |
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75:12 | . What are we doing? We're our internal clocks Now. I remember |
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75:16 | would be driving in and I would this commercial all the time and I'm |
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75:19 | gonna remember the name of it. there's a condition in blind people where |
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75:24 | circadian rhythm basically starts modifying over the today. And I kind of talked |
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75:30 | that. You can do that in and mice. It's because our internal |
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75:32 | really runs it like 23 hours. so we don't you know, we |
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75:37 | we kind of shift naturally a person can't see because they have a failure |
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75:43 | the photo receptor cells. Right. cells are functional and so what's happening |
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75:50 | their system is being modified and modulated this. It's really kind of |
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75:56 | So their brains still detect light. just they don't detect light to |
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76:02 | That kinda makes sense. Yeah. other ones that we already mentioned are |
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76:06 | pigmented epithelial cells uh they these are ones that make up that uh that |
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76:14 | layer and as I sit said already the other one, they basically capture |
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76:18 | the photons. All right, So I want to focus, I'm just |
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76:26 | to see how much time we have . None. All right. I'll |
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76:31 | here because if I don't stop then dress. It doesn't make |
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76:37 | All right. So when we come on Tuesday, we're gonna learn how |
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76:41 | eye works. Gonna be a lot fun, |
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