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00:01 | All right, good morning campers. you ever heard that before? |
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00:06 | I mean, no, I actually heard someone do that at |
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00:10 | No. Ok. They actually did well, all right. Uh, |
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00:14 | just gonna go briefly over a couple them. Now this is the week |
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00:16 | everybody's having meetings. So there's like of them. Um, actually not |
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00:22 | many, but there are a So you should be able to find |
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00:25 | that you're interested in. This is , uh, or Docs. It's |
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00:28 | Mega. It's a medical service They're meeting on the 31st, which |
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00:32 | Wednesday tomorrow at 5 30 in that . So address Arnold two. |
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00:39 | next on our list is a uh, society at do, |
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00:44 | which is a pre, uh, Thursday from 8 30 S E C |
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00:52 | . Notice everyone is saying free you can get yourself fed this |
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00:56 | All right. A CS, they sent me something and they were offended |
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01:00 | me all the way. So September , uh, they are meeting at |
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01:05 | PM in S E C 100. the big room over in S E |
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01:10 | uh you can go check them out you're interested. And yep, |
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01:13 | lunch is provided uh Alpha A Um They are having their meeting next |
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01:21 | on Tuesday. So a week from and uh social work one oh one |
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01:25 | 6 to 8 PM. Uh free and free food. So you can |
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01:29 | both of those. Um Also, the way, if you miss any |
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01:34 | these, just email me and I'll them online. I just don't ever |
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01:37 | them because no one ever asks me . Uh, so they, I |
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01:41 | just post this whole list. All . Um, as a, |
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01:43 | is also a pre society, it's local one here and it's gonna meet |
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01:48 | Wednesday from on September 7th 6 30 8 30 it's gonna be in S |
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01:54 | C 100. So the big classroom in S E C once again, |
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01:58 | , free food and then that leads to where we're going to be |
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02:02 | So a lot of things going we say something what's going on? |
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02:12 | the pain for the blood. So students, right. Wow. |
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02:24 | yeah. Go check out volleyball You're not, you've already paid for |
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02:28 | tickets. Go check them out, ? Are you guys gonna be number |
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02:33 | in the country and easy? go check them out. All |
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02:38 | Uh, as we begin here, want to kind of remind you where |
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02:41 | left off on Thursday we were boring to death with chemical compounds. You |
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02:46 | we were talking about Adam and most you were sitting there rolling your eyes |
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02:49 | . I can't believe he's talking about still. And what we were talking |
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02:54 | was really that last level, that of electrons important because it allows atoms |
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03:03 | work together, come together to form are called compounds and what we're gonna |
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03:10 | and we're going to shift gear before go into the actual molecules that are |
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03:16 | in biology, specifically in physiology and our bodies work. And what we're |
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03:20 | do is we're going to look at and you see that really water, |
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03:24 | gonna talk about water in it like kindergarten stuff. And it's like what |
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03:27 | of water is the medium in which body are able to do the chemical |
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03:34 | . So we need to understand why is so important for the body. |
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03:38 | then what we're gonna do after that we're gonna talk about mixtures and solutions |
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03:44 | the world. But we need to that really that fluid in our body |
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03:48 | different types of properties depending upon what of materials are found in it. |
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03:53 | then we're going to finish up with just some terminology just to really kind |
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03:58 | put you to sleep and make sure miss your next class. Does that |
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04:01 | good? You're like, I don't . All right. So chemical compound |
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04:06 | a compound is a substance consisting of or more different elements in a fixed |
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04:13 | . People think chemistry is hard. is not hard. Chemistry is baking |
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04:19 | scientists. Have you ever baked? bakes? Excellent. Do anyone here |
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04:25 | how to make pancake? It tells exactly the name. What's in the |
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04:31 | ? A pound of flour, a of butter and a pound of |
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04:37 | which is a dozen eggs. That's pound kiss. Do you think you |
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04:41 | all make a pound cake? One in the farmer is like, I |
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04:46 | do that and you could, it's hard, is it? No, |
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04:51 | all it is a fixed ratio. a 1 to 1 to one. |
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04:53 | you look at chemistry, that's all is. It's 1 to 3 to |
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04:56 | to 6 to 12 to 5 to . You know, it's all over |
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04:59 | over again and once you figure out all ratios, it's like, |
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05:02 | this is easy and baking is That's what chemicals are. They're just |
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05:07 | ratios. And we have all sorts different types of chemicals. They fall |
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05:10 | two basic categories. We refer to as being ionic in nature and we |
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05:14 | to them as being as molecular in . Right now. I have a |
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05:19 | of chemicals up here. Some of you recognize and some of which you |
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05:22 | go. I have no idea what are but the top one is sodium |
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05:26 | or table salt. Good. We water and then we have carbonic acid |
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05:34 | are going up. It's an important of the body. So you kind |
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05:37 | become aware of it. And then , the bottom one is basically, |
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05:41 | me, glucose. All right. that's another one that's very, very |
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05:44 | . And I throw them up here for you to memorize. All |
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05:47 | there's another chemistry class, but these different types of molecules that have different |
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05:52 | of ratios using very similar chemicals. mean, you can see with the |
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05:57 | of sodium florida up there and they into these categories because of the way |
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06:01 | these atoms come together. And so we're going to look at first is |
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06:05 | gonna look at ions and simply put an, is an atom or a |
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06:10 | of at. And the only way you can get a positive or negative |
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06:17 | is if you gain or lose electrons that outer valence show. All |
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06:22 | So what we have up there is have sodium, we have uh |
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06:27 | All right. Now, sodium has electronic balance shell and chloro uh the |
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06:33 | has uh seven. All right. , we said that, that valence |
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06:39 | becomes happy if it's completely filled when completely filled, it has eight |
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06:45 | And it, what we refer to as is the all or nothing |
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06:47 | Either you have eight electrons and you're or you don't, in which |
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06:53 | you either want to gain or lose . Now, if you're a |
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06:57 | what would you want to do with extra electron? Would you like to |
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07:00 | to gain seven or would you like try to lose one, lose |
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07:04 | All right. And so that's what willing to do. It's saying I'm |
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07:07 | to give up this one electron because makes me a stable atom. And |
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07:12 | you can see in that, in shell there's, there's eight electrons. |
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07:14 | so it's very, very happy. , once you do that, what |
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07:18 | done is you've lost a negative charge you've now because you've lost that negative |
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07:24 | , which formally was balanced. Remember we said electrons and protons are equal |
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07:29 | an atom. So if you lose negative charge means you now have an |
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07:33 | positive charge. And so we say this ion is now positively charged. |
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07:39 | refer to it as a cat ion now. It's really easy to remember |
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07:44 | ions because it has the plus sign the middle of the word. See |
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07:49 | t even though they put that little , it's a plus sign. So |
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07:54 | never forget it. All right. that's a cad iron. A cad |
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07:57 | is simply an ion with a positive . Now, chlorine is has seven |
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08:05 | in its valence shell. If it to get to eight, it's easier |
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08:09 | gain one than it is to lose . And so if there's an electron |
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08:13 | it can, can control up, means it becomes happy at which point |
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08:18 | gained an electron at which point we say that it is an anion and |
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08:24 | negatively charged. Now, sodium and by themselves are not attracted to each |
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08:33 | . But once that sodium gives up electron and once that chlorine gas, |
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08:39 | electron, we now have a positive ion and we have a negatively charged |
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08:44 | . And what do we have something is attracted to something else? Would |
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08:49 | agree that opposites track? Yes. , maybe kind of, yes, |
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08:55 | do. At least in science they elsewhere. Who knows? All |
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09:00 | So that's, that's really what an is. It's simply an atom or |
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09:05 | that's given up electrons or gained I'm putting the s in because it |
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09:10 | be one or more. And now you have is you have a charge |
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09:14 | with that atom or molecule and the names are cat ion and anion. |
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09:19 | so here is an example that all , prior to them giving up and |
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09:30 | their electrons, they weren't attracted to other. It's kind of like those |
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09:34 | coms, right? The girl who's the glasses and it looks like the |
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09:39 | and then you get that makeover and of a sudden she's like the star |
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09:44 | everybody is attracted to. That's kind what's going on here, right? |
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09:49 | not attracted to each other in that , when they, uh when sodium |
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09:54 | that electron and chlorine doesn't. But you pass them off, now you've |
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09:59 | the chargers and off, they Right. So that's really what an |
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10:03 | bond is. It's the attraction between cat and an ant. Now, |
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10:08 | salts are, that's why it's a simple one. But many salts are |
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10:15 | by basically having either one or two that they need to gain in their |
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10:21 | shells or they have 1 to 2 that they can lose. So if |
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10:26 | looking at the periodic table, you pretty much find, figure out what |
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10:29 | salts are going to be made of right there in those first two |
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10:33 | in the last two columns before the gasses. Now, if you take |
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10:39 | molecule that there's no water available, bond is incredibly strong. All |
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10:48 | it takes a lot of effort to out the two ions from each |
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10:52 | But if you take that same compound put it in water, it dissociates |
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10:58 | , very quickly. And the reason that is because of the nature of |
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11:02 | . All right, we're going to about that a little bit more. |
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11:04 | no longer the same degree of attraction water is a polar molecule and it |
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11:09 | creates a uh a kind of protective between the ions. There's an attraction |
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11:17 | the water and the ions themselves. So that's why those molecules just kind |
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11:21 | fall apart and then they're like, yeah, I'm kind of happy because |
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11:24 | surrounded by water. So in water when it's a solid, it's a |
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11:31 | bond. Now, when you think , of molecules, you typically think |
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11:37 | electron share, you don't really think these ions. You think of the |
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11:41 | sharing here. What you do is forming a molecule from two or more |
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11:46 | where, what they're going to do they're going to share an electron. |
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11:48 | like when you and your friend go , oh, I don't know. |
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11:52 | say you forgot your wallet and you're , hey, can we share that |
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11:58 | ? And your friend is nice enough say, well, sure, I'll |
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12:00 | my lunch with you. So you get something out of the deal and |
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12:04 | , your company, you get food so if the atoms or excuse |
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12:15 | the elements are of the same type they come together, then what we're |
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12:20 | called the molecular element. Now, familiar familiar with oxygen, oxygen. |
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12:25 | can see up there that's a second . Let me see if I it's |
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12:31 | this one really, really weird. , that's how we anyway. All |
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12:43 | here. I don't think it All right. So you can see |
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12:47 | up there, basically two oxygen atoms together form a stable molecule. That |
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12:52 | now has eight electric each of those now have, has shared between them |
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12:57 | electrons in each of their outer valence . Right. Now, if you |
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13:02 | two different types of elements, two more different types of elements, and |
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13:05 | you're doing is you're just creating a compound and these are what we're kind |
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13:08 | familiar with. And so when you at a molecule, it has a |
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13:13 | formula, right? And it basically tell what the components inside a molecule |
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13:18 | their ratio. So for example, have carbon dioxide up there, it |
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13:22 | one carbon and two oxygens. All . And you see there is the |
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13:27 | acid, it basically has a ratio one carbon to two hydrogens, three |
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13:32 | . But just in knowing the molecular , you don't only know a lot |
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13:37 | the molecule. So humans have also that there is a chemical formula, |
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13:41 | is a shape to the molecule. so we can represent the molecular formula |
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13:46 | its actual arrangement. So carbon you can see here is a range |
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13:51 | you have two oxygens bound to the , which is centrally located. And |
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13:55 | we have here is a double bond is represented by two lines look like |
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13:59 | signs. You can see uh by or sorry, carbonic acid. Now |
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14:04 | you the shape of the molecule. doesn't look anything like the molecular |
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14:08 | You have a hydroxyl group attached to central or two hydroxyl groups attached to |
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14:13 | central carbon. And you have a bond in oxygen to that carbon as |
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14:18 | . Now, you're sitting on double , single bonds. What are you |
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14:22 | about here? We'll get to that just a moment. But what this |
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14:25 | , it allows us to see the of the atoms to one another. |
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14:31 | it gives rise to our understanding of molecular formula is not only important, |
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14:37 | actually the shape of the molecule we what are called isomers and isomers simply |
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14:42 | molecules with the same molecular formula, with different shapes up here. What |
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14:49 | looking at is we're looking at three sugar oil. All right, on |
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14:53 | left, we have glucose in the , we have black and on the |
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14:57 | , we have frutos, each of molecules has the same molecules or |
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15:05 | All right, nice simple molecule You can see looks a lot like |
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15:11 | . The difference is around four It's the arrangement of the hydroxyl group |
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15:16 | the hydrogen they're flipped and that little is enough to make those molecules vastly |
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15:24 | . And then we have fructose, is what makes sugar taste good. |
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15:29 | what we actually crave, you high fructose corn syrup. The reason |
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15:33 | like it is because it has lots that and less of that, even |
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15:38 | glucose is what our body actually And you can see just by looking |
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15:42 | it, it's like, wait a that looks really, really different. |
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15:45 | you agree. Does it look different that? Yeah. OK. So |
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15:49 | binds molecules, other molecules, other in a very different way because of |
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15:54 | shape, right? But we can convert between the two, all |
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16:00 | So isomers are molecules that have the molecular formula but very, very different |
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16:08 | arrangements. And because of those different arrangements, they behave differently not only |
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16:14 | the body but in general chemical So coming back to the and so |
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16:23 | , if you think chemistry, nothing far is, would you agree chemistry |
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16:30 | going, oh my goodness, this like a foreign language. What we're |
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16:36 | at is we're looking at the types covalent bonds that can be formed. |
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16:40 | , up at the top, we what is referred to as a single |
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16:43 | bond. You'll notice that we're using of the exceptions to the, the |
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16:49 | says that you need to have eight in the outer shell, the one |
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16:53 | that doesn't satisfy this is hydrogen, other molecule which has a complete outer |
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17:00 | shell, but it's not an octet helium. Those are the two molecules |
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17:04 | the top of the periodic table. right, they don't have enough electrons |
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17:09 | fulfill the octet rule. So they're exceptions to it. But what |
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17:14 | what we can see in this is can see fulfilling the rule about fulfilling |
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17:20 | outer shell. And so in this , what we have is we have |
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17:23 | electrons that need to have that we to share between these hydrogen hydrogen. |
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17:28 | has one electron. It wants to two if I take one hydrogen and |
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17:32 | hydrogen and bring it together and allow to have each share that electron, |
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17:36 | means each of them has that electron that nucleus. And so both of |
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17:42 | are satisfied and happy. All So the electrons spin equal times around |
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17:48 | nuclei. And that's what holds this together. So what we're doing when |
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17:53 | doing the covalent bond is we're sharing between two atoms. All right. |
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17:58 | that, that electron circles about nuclear regard to the second picture, what |
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18:03 | have here is a double covalent Now, what we're looking at is |
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18:07 | looking at oxygen and we said oxygen to fulfill eight electrons, it needs |
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18:13 | have eight in its outer shell. right. And if you look what |
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18:16 | doing is we're sharing two electrons from oxygen atom. All right. The |
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18:22 | on the left says here, I'm lend you two so that you can |
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18:25 | eight. And then the one of right I'm gonna lend you to so |
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18:28 | you can have a. So these are, are spending these eight electrons |
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18:33 | each of them are sharing, are an equal amount of time between both |
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18:37 | are circulating both nuclei in their outer . And so that allows for |
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18:43 | them to have that stability. And down here on the bottom, that |
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18:46 | be an example of the triple bond . What we're doing is we're sharing |
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18:49 | electrons, right? So the one the left is sharing three electrons, |
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18:53 | on the right is sharing three electrons them, they have six that they're |
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18:56 | together. And that means that you two that they're not sharing. And |
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19:01 | that would be a nitrogen atom. right. Now, what I want |
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19:07 | do here is I want to turn . I said about electrons on |
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19:12 | What do I say when you think electrons, what do you need to |
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19:15 | of them as do you remember? they supposed to be particles? Do |
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19:20 | care if they're particles? No, said there was something else about |
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19:29 | Remember you won't want to guess, a look back and say or that |
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19:45 | does it have to do? Don't , don't be shy. I'll have |
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19:48 | walk in the office somebody energy. you. That would be loud. |
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19:56 | go all right. Energy. Think electrons as energy. Remember energy to |
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20:00 | the electronic place and then when you the electronic, it has so much |
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20:03 | that it wants to go someplace right? It's like a dog on |
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20:06 | leash, right? And so you think about it is order the heat |
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20:11 | , of these two atoms together. you're doing is you're sharing electricity or |
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20:16 | energy. So when you bring in bond between these two, you're adding |
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20:21 | to the system that it basically holds two things together. And if you |
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20:24 | to break the bond, you have tank energy and add more energy. |
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20:27 | the electron becomes so excited that it away and that's just going to break |
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20:31 | bond, right? How do you have cards? You know what you |
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20:37 | in your car to make it run ? All right, if I take |
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20:42 | match and I take it to what's going to happen to it? |
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20:46 | gonna explode. So, if I'm gasoline in my car, what's the |
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20:50 | doing to the gasoline? Making it ? It's exploiting the energy in the |
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20:57 | bonds between the carbons in that gasoline that octane and the hexane and the |
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21:02 | and all the other aims that are gasoline. All right. It's basically |
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21:07 | controlled explosion. And all you're doing you're adding a little bit of energy |
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21:11 | the form of a spark that releases energy when you put food in your |
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21:18 | . It's the same thing. A is basically a bunch of molecules that |
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21:23 | held for a bunch of atoms that held together by electrons. All I |
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21:28 | do is put a little bit of in it and I can release more |
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21:32 | . Kind of neat. Right. really what it is. And so |
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21:37 | can think about this, every bond I form a single bond is some |
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21:42 | , a double bond is greater energy bonds. That's a lot of |
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21:47 | So you're going to need to put more and more energy depending upon the |
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21:50 | of bonds you have between the individual . That makes sense, kind of |
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21:56 | of. All right. So looking a little bit further, you can |
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22:00 | here a little bit more complex You can see methane over there, |
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22:05 | , you can see it has it is sharing an electron with four |
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22:09 | hydrogens. So each hydrogen now has electrons circulating circling it. The carbon |
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22:14 | has eight, there's carbon dioxide. can see there's a double bond between |
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22:19 | carbon and the oxygen. Each carbon has eight electrons circulating in valence |
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22:24 | Each oxygen has eight based on the of electrons that have been shared. |
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22:29 | then over there, there's ethanol called friend. Oh Yeah, I forgot |
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22:36 | guys a freshman. You you'll learn basically, you can see how we |
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22:45 | every atom in a molecule is going fulfill that octet rule with the except |
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22:50 | the hydrogen that are going to have electrons in its outer shell. |
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22:56 | what we can do oops is if look at molecules, we notice that |
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23:02 | molecules don't possess a bond that is shared between the atoms in that |
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23:10 | What happens is is that some atoms electrons that spend a little bit more |
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23:16 | circling one nucleus, then circling All right. And there's many reasons |
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23:23 | all this, which we're not going go into. And what that, |
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23:25 | happens when that, when that what we end up with are what |
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23:29 | called polar molecules. We refer to a bit as the degree of electron |
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23:35 | . It's that attractive force that pulls electron towards one nucleus and away from |
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23:41 | . What we're looking at here is looking at a non and we're looking |
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23:46 | a triglyceride, which is a fancy for fat, right? You can |
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23:52 | here what we have is this long chain and this long carbon chain looks |
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23:57 | awful lot of like with itself, it? I mean, you have |
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23:59 | and two hydrogens, carbon two carbon two and just kind of keeps |
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24:02 | on and on and on and Not a lot of difference along the |
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24:05 | . And so this would be a that lacks polarity. It looks |
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24:09 | very similar. So there is nothing it that causes electrons to be pulled |
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24:14 | particular particular direction or another. But you look at a molecule like |
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24:20 | all right, water has an right? That wants to have eight |
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24:26 | circulating around it. And then it these little tiny hydrogen atoms that have |
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24:32 | one electron and it's trying to just one electron. And so what ends |
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24:35 | happening is that the oxygen tends to onto the electrons a little bit more |
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24:40 | the hydrogens do. And if the holds onto the electron a little bit |
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24:45 | and electron is negatively, that means oxygen tends to be a little bit |
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24:50 | negative than the hydrogens do. And now what we have is we have |
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24:54 | molecule that is more negative on one than on the other. And now |
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25:00 | can say that's pole because if you're little bit more negative, what are |
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25:04 | gonna be attracted to something that's Right? And so that's what's going |
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25:09 | happen is they're going to arrange themselves such a way that they orient towards |
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25:14 | that's positive on that negative side. conversely, the positive side of that |
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25:19 | is going to arrange itself but its or facing something that's negatively charged. |
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25:25 | so polarity and these polar bonds lends to how molecules arrange themselves and ultimately |
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25:33 | with their environment. So what all stuff says up there is just where |
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25:40 | electrons are spinning. If you're a covalent bond, electrons spin equal time |
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25:46 | the molecule. So there is no . And when you are a polar |
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25:50 | bond, you basically have a bond the electrons tend to spend more time |
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25:55 | one side or the other, we another type of molecule, we need |
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26:01 | be aware of empathic. Now, said on Tuesday last week that in |
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26:09 | biology, right? And when you at this word, you see a |
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26:14 | big word that doesn't mean a lot you, but to a person who's |
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26:18 | in biology it tells certain things, know, you have that first half |
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26:24 | . Have you seen that first half a word? Anywhere else? |
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26:28 | What do you know about amphibians? . Sort of in water and sort |
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26:33 | out. Right. I mean, of an amphibian. What is an |
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26:36 | name? One? You should be to go one off the top of |
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26:39 | head frogs, right? And you the life cycle of a frog way |
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26:42 | in life sciences, back in sixth , you got the tadpole or you |
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26:46 | the eggs and then the tadpole swim the water and then eventually it starts |
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26:49 | legs and then it hops out of water and loses its tail. And |
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26:51 | you've got your frog. All That sound familiar, kind of. |
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26:56 | right. Well, ay means half, up, half in, |
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27:01 | out, an antipathy molecule is half and half non pole. What, |
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27:09 | that possible? Well, what that is part of the molecule doesn't have |
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27:15 | sort of polarity. In other it behaves like a nonpolar molecule, |
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27:19 | then the other half of the molecule this imbalance of electrons. And so |
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27:23 | becomes polar. And so if that's case, that means the polar side |
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27:27 | going to try to associate its cell other charged or polarized atoms. And |
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27:33 | the non polar side is going to excluded from the group molecules excluding other |
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27:41 | . How rude. All right. what we're looking at here is a |
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27:46 | example. All right, this is molecule you'll need to know this is |
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27:49 | phospho lipid. You've taken biology ever your eyes. When you know this |
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27:57 | , fossil lipids have a polar head these long tails, fatty acid tails |
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28:03 | are nonpolar. What that means is if you stick by water, those |
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28:09 | are going to be excluded from the . And so if you have a |
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28:11 | of fossil lipids, they're going to themselves in such a, such a |
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28:15 | that those fossil lipid tails are hidden the water and those heads are going |
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28:19 | be associated towards the water. And it arranges itself into a unique pattern |
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28:27 | we're going to see that it's these that are responsible for making up the |
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28:32 | membranes of your cells and it creates compartments of your body which are responsible |
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28:38 | how your whole body works. So this, your body cannot be why |
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28:43 | an important molecule. All right. they exhibit both the polar and the |
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28:49 | polar character are simply weak attractions between . That's like when you watch |
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29:01 | when I guys, I'm gonna give all our secrets in this class. |
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29:04 | just my nature. It's like watching watching girls, you know, they |
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29:10 | kind of do this. It's a attraction. It's like, yeah, |
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29:12 | attractive. She's attractive. Ok. , my attention is back to video |
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29:16 | . Oh, yeah. There's another , you know, it's a weak |
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29:20 | . Hydrogen bond is simply weak attractions a hydrogen and an atom. All |
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29:25 | . And they associate themselves in such . Part of it is because of |
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29:29 | polarity that we're gonna see. um, you know, as we |
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29:33 | forward with, there's a small bridge takes place. It's kind of like |
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29:37 | gaze of the guy. It's ok, I've got that bridge. |
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29:40 | . Now I'm broke. It's a , very short, small, weak |
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29:45 | , not very strong bond. So doesn't have a lot of energy that |
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29:50 | into it. But if you have lot of bonds, they can form |
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29:55 | strong bonds together. Right? It's of like, um, uh, |
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30:02 | , well, you're too. You remember ant or not ants, but |
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30:05 | life. Do you remember Bug's Ok. So I'm hitting that sweet |
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30:09 | of where you guys were like seven olds. Ok. Do you remember |
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30:12 | happened at the end of Bug's How did they beat the grasshoppers? |
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30:17 | ant can't stand up to a How many ants do you need? |
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30:21 | of them? All right. That's what it is. Uh, anyone |
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30:25 | have a sticky note tape, any those things, ever wonder why they're |
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30:32 | to stick and then you're able to them hydrogen bombs. Yeah. There |
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30:37 | go. All right. There you . Anyone ever seen a gecko? |
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30:42 | is Houston. You should have at seen one gecko in your life. |
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30:45 | have them in your bedroom at Chirping. Ok. All right. |
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30:50 | can run up and down glass Have you noticed that they can run |
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30:54 | the ceiling? And you're like, do you do that? Well, |
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30:56 | reason they're able to do that is of the next type of attraction it's |
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30:59 | the vander walls force. All this is a very, very weak |
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31:04 | in terms of its strength, about . But you get a lot of |
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31:07 | vanderwal interactions taking place and that's gonna for a lot of stickiness. And |
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31:12 | what geckos do on their feet, the soles of their feet. They |
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31:15 | these little tiny pads and they're not suction cups. So they're not going |
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31:19 | stick, stick, stick, stick. What they do is they're |
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31:22 | small and there's so many interactions that them to literally stick to the surfaces |
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31:28 | they're crawling up and down because of forces. All right, there are |
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31:33 | what are called hybrid hydro excuse hydrophobic interactions or exclusion. This is |
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31:40 | molecules to exclude other molecules typically. it is is that a polar material |
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31:45 | a nonpolar material in it. Um you've ever seen vinegar and oil, |
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31:50 | you ever seen that all Right. ladies are all shaking their head and |
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31:53 | . Yeah, I know. Vinegar oil. Guys go. Well, |
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31:55 | the stuff that you put on guys, salad is the green stuff |
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31:59 | women eat. Right. If you vinegar and oil and put them in |
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32:06 | container, do they mix ladens? , you have to do something special |
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32:11 | get them to mix. And the for that is because the water or |
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32:14 | vinegar portion says fat oil, you nonpolar. I am polar. You're |
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32:23 | allowed to come and join me. so it excludes it. That's what |
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32:28 | hydrophobic interaction or exclusion is so Are you guys with me? Is |
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32:34 | easy? Not easy. Are you to wonder why you picked science and |
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32:41 | Law Mueller? You don't know that too young. All right. But |
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32:51 | promise you what we're gonna do is gonna move from these very basic types |
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32:54 | interactions. We're gonna move into So we can understand the environments in |
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32:57 | molecule, water is, the substance which our molecules are bathed in our |
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33:04 | . All right, water has some structures and special properties. It's tetrahedral |
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33:10 | shape. You can see if I that oxygen molecule and have my two |
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33:13 | off to the side. That's a . But if you consider the three |
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33:17 | , the ones that are not being between the hydrogens and the oxygen, |
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33:20 | put them in two other corners And you can see there's a tetrahedron, |
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33:24 | you take organic chemistry, you'll get model this almost every day and then |
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33:28 | going to bang your head against the again, wondering why you didn't go |
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33:30 | law school. All right. So is its natural shape. And so |
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33:36 | it's a polar molecule, because the spend more time near that oxygen than |
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33:41 | does have here in the hydrogen. now have this electro negative or the |
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33:45 | negativity that is towards the inside. so what's going to happen is if |
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33:50 | got a whole bunch of water, going to arrange themselves so that the |
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33:54 | oxygen is going to be pointed towards positive hydrogen of another molecule. And |
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33:59 | arrange themselves in a tetrahedral pattern forming bonds between them. It's a unique |
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34:06 | of water. All right. And what we have now is we create |
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34:10 | massive lattice uh uh when you're looking a fluid of pure water, |
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34:20 | in the body or in general water in three states, right? You |
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34:26 | aware of what we call them, solid form of ice. This is |
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34:30 | a good thing in the body, breaks cells and destroys things. So |
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34:34 | typically don't have solid water in our , but it does exist in this |
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34:39 | . All right, most common is liquid form, right? That water |
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34:46 | a liquid form, it's forming these bonds, it keeps the water close |
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34:51 | and holds the water uh uh in . And then we have vapor. |
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34:57 | see this uh again, uh winter , we become very, very aware |
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35:02 | it. When you're breathing in and . You can see the vapor. |
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35:06 | right. But water exists in a in our body, in our |
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35:09 | We're moving water in and out in vapor form. So these three state |
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35:20 | in the body, we can think water as having multiple functions that plays |
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35:23 | role in transport that demonstrates some very transport. Looking at cerebral spinal fluid |
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35:28 | here, we're looking at the cardio here. When you think of your |
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35:32 | , you've got to remember that 50% that blood is water, right? |
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35:38 | water plus other stuff. The cerebral fluid is water plus other stuff. |
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35:42 | other stuff is your body is moving for use by the different cells all |
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35:48 | your body plays a role in And that mean me join up |
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35:55 | All right, if you didn't have fluid in there, those two bones |
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36:00 | be pressed up against each other with the way to your body on it |
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36:03 | then you run against each other, each other down like a mortar and |
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36:07 | by creating synovial fluid, your body a lubricant that allows these two services |
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36:14 | out of each other. All So water serves that the cushions and |
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36:19 | , we're going back through the spinal , it serves kind of as a |
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36:22 | a barrier and a a protective water is not particularly compressible because of |
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36:30 | between those molecules. All right. so when you try to, so |
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36:37 | allows us to have something in for example, our brain can actually |
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36:43 | in and on top of and then surrounds the brain so that the brain |
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36:47 | move around so much inside the it's very, very protective. And |
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36:54 | lastly, it's a way to transport out of the body. In other |
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36:57 | , it allows us to create Uh By the way, this is |
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37:01 | you don't have friends with phones because take pictures of you and put you |
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37:03 | the internet and end up in my . So, you know, you |
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37:10 | to get things out of your well, dissolve it in water and |
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37:13 | . It goes very, very All right. So water is used |
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37:18 | many, many different things, has characteristics, you're also aware of |
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37:23 | right? And I'm gonna try to these with these pictures. So we |
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37:26 | cohesion and cohesion is simply the attraction of those between when water is put |
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37:34 | something, it doesn't break those they tend to a cluster together. |
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37:39 | if I were to say, for , take a drop of water and |
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37:41 | it on a table, that water just spread out a molecule molecule |
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37:45 | it bows up because all of those bonds they are uh they're holding together |
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37:53 | that's the cohesion. So the drop water in the skin up there is |
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37:56 | result of cohesion, surface tension is inward pull of those water molecules |
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38:04 | So basically, when you have these molecules again, it's the hydrogen bonds |
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38:09 | it doesn't want, they don't want break, they wanna hold together. |
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38:12 | think this is one of the coolest ever. This woman breaking the surface |
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38:15 | the water, you can see that water is being held in place. |
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38:18 | though she's broken past the surface, water is stretching as her body breaks |
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38:25 | . And it's only once she creates distance that the hydrogen bonds are gonna |
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38:29 | broken. So she passes through it now. Have you ever seen water |
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38:36 | ? You've seen? Why can these stay on the surface of the water |
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38:40 | of the surface tension of the They don't create enough force to break |
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38:44 | that you and I, well, a little bit bigger and that's why |
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38:48 | we step on water, we go through and here's the adhesion, adhesion |
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38:56 | the stickiness. All right. And , once again, it's hydrogen |
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38:58 | but this time, it's not between polar molecules of water, it's between |
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39:02 | and another polar molecule. And so is why the water stays held on |
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39:08 | nose because it's adhered to the surface once the weight of that water gets |
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|
39:14 | enough. Will it actually break and ? So, water behaves in a |
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39:20 | unique way because of these hydrogen bombs also because of these hydrogen bonds, |
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39:27 | behave in a very unique way to what temperature is. And isn't, |
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39:34 | will make a lot of sense? temperature simply is the measure of the |
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|
39:38 | energy. Do you notice how everything coming back to? All right, |
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|
39:42 | you get to physics and they're starting try to confuse the heck out of |
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|
39:45 | just remember everything always move back. right, simply put the temperature is |
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|
39:51 | random movement of particles. The energy a particular substance right now, what |
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|
39:57 | said about those water molecules is that interacting by hydrogen bombs. A bond |
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40:03 | simply the energy shared between molecules. now, we talk about covalent |
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|
40:09 | but it's true about a hydrogen So water because of those hydrogen bonds |
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|
40:14 | able to absorb and release energy in very unique way. Heat or temperature |
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|
40:20 | a unique way has a very high heat. In fact, they use |
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|
40:24 | as the standard. Basically, uh specific heat is the amount of heat |
|
|
40:29 | to raise the temperature of one g water by one degree. All |
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|
40:34 | So that's how we know what the temperatures are. Is because of the |
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|
40:39 | heat. Water also has a that means that there's a lot of |
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40:46 | that needs to go in to convert form of water from one to the |
|
|
40:50 | . To put another way. It's what is the temperature at which water |
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|
40:57 | ? 100 degrees? C, what's temperature at which water freezes? Zero |
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41:01 | ? C? So if I take and bring it up to 100 |
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|
41:05 | does it immediately turn a steam? , you have to add in more |
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|
41:10 | more and more energy before that molecule away and becomes a vapor. In |
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|
41:17 | words, you have to add energy break those bonds before the water |
|
|
41:22 | And this is good news for us this is how our body cools |
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|
41:26 | It means that while we're producing energy our movements, which is really how |
|
|
41:31 | produce heat. What happens is, as we, as our body temperature |
|
|
41:35 | , we move that warm water through body, that's our blood and we |
|
|
41:40 | it to the surface which then warms on the surface of our skin, |
|
|
41:45 | is sweat or Houston humidity, And then that sweat, when that |
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|
41:51 | absorbs enough energy, then the sweat and off goes the energy. This |
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|
41:58 | how we cool ourselves, right? take advantage of that property. So |
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42:05 | able to absorb lots of energy because the heat capacity and we're able to |
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|
42:10 | it away because of the heat of . Have you ever taken rubbing alcohol |
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|
42:16 | put it on your skin? What it feel like when you do that |
|
|
42:20 | really, really cool, doesn't Why say it evaporates? Why does |
|
|
42:27 | , it evaporates at a lower temperature water? Does? Its heat vaporization |
|
|
42:32 | much, much lower. So it goes away. But notice it |
|
|
42:36 | it causes the same effect. It's cooling effect. Just like sweating cools |
|
|
42:40 | down. All right. That's what heat vaporization does. Now, water |
|
|
42:45 | say is dissolved in what basically all substances in your body are gonna be |
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|
42:50 | in water. When we say it doesn't mean break the molecule |
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42:57 | dissolve, disperse and spread evenly. you take a thing of pure water |
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|
43:03 | pour in cool cool, goes straight the bottom and it hits the ground |
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|
43:07 | it sits there. But if you it infinite time and put it into |
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43:11 | enclosed environment, eventually, all those aid molecules, all that guy who |
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|
43:19 | , right? And then we get impatient, what would we do |
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|
43:23 | Shake it up or something like But given that, that's what it's |
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43:27 | to do. Water is going or molecules to solute the stuff that's dissolved |
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|
43:32 | our water, which is the sol is going to move so that everything |
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43:37 | equally dispersed. When you came into classroom for the first time, you |
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|
43:42 | around and you looked for the most area, didn't you? People in |
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|
43:47 | front are nodding, their heads Yeah. Right. You're like, |
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|
43:51 | right. I'm the first person I to pick my spot and then you |
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|
43:54 | in and you sat down and you're , please, no one sit by |
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|
43:58 | , right? You're like a molecule dispersed as well as you can and |
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44:02 | more people came in, you kind dispersed equally around the room and then |
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|
44:06 | of a sudden more people started showing and now you have to start sitting |
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44:10 | to people and you're like, please sit next to me. Please don't |
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44:13 | up. Hi, how are All right, molecules disperse just like |
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44:20 | guys like to disperse you like that around you. And that's what happens |
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|
44:27 | , substances that are attracted to and water referred to being hydrophilic literally means |
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|
44:34 | alive. All right, hydrophilic If they're water, loving must have |
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|
44:40 | same characteristic of water. What it's of water. It is not the |
|
|
44:44 | is an herb polar, right? substances that are found in water must |
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|
44:51 | the same characteristics. They must be in nature, right? They either |
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|
44:56 | a charge positive or negative or they have the same sort of degree of |
|
|
45:03 | activity, right? They're polar right . Some substances i substances or compounds |
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|
45:10 | are referred to as electrolytes will dissociate distribute in water. So if I |
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|
45:17 | salt and put it into water, sodium and the corn are going to |
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|
45:22 | from each other. Remember, they're attracted to each other, but because |
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|
45:26 | charged, they're going to dissociate and going to be surrounded by the |
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|
45:30 | And that's what you see down here the bottom. So you can create |
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|
45:33 | hydration cells where you have these polar arrangement cells around this charged particle and |
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|
45:39 | cool, we're attracted to you and molecules or the atom is going |
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|
45:43 | and I'm attracted to you too. I don't need to be attracted to |
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|
45:46 | other ion over there. You guys doing enough to satisfy the attractive need |
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|
45:53 | both molecules do because remember your you have an electron negative side and |
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|
45:57 | positives side. And so you can yourself depending on what type of uh |
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|
46:02 | is around you. All right. reason they're called electrolytes is because they |
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|
46:08 | electricity. Uh I'm sure you can home and take a thing of pickle |
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|
46:12 | , put in two electrodes and probably up a light bulb or something like |
|
|
46:17 | . All right. There's all sorts fun physics experiments you can do |
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|
46:21 | I don't even remember. They're also , not, these are things that |
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|
46:27 | dissolve readily. All right, they'll but they won't dissolve and won't break |
|
|
46:32 | because they're not what we're looking at there is another molecule that is not |
|
|
46:39 | electrolyte, it's glucose, right? a small molecule because it has these |
|
|
46:43 | groups sitting on the side, these these alcohol groups. All right. |
|
|
46:48 | what it does is that the water arranges itself in such a way so |
|
|
46:51 | those groups and those hydrogens are are appropriately satisfied. All right. |
|
|
46:59 | they arrange themselves, but it doesn't electricity, it doesn't do anything. |
|
|
47:03 | just allows for that molecule to become distributed. Right now. There are |
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|
47:11 | molecules that are hydrophilic. All this is water clearing. These are |
|
|
47:14 | fats, these are molecules that are pod. And what they'll do is |
|
|
47:19 | the water says I'm not attracted to . So you need to go |
|
|
47:22 | And that molecule says that's financial. so it basically arranged itself in such |
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|
47:27 | way that it's as far away from as the pop gets. All |
|
|
47:30 | So again, you can think of , right? You think of any |
|
|
47:37 | uh aqueous solution that fat basically creates bubble that's as far away as water |
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|
47:42 | it possibly can get. All it tries to move away. And |
|
|
47:48 | mentioned the amp paic molecules, the molecule like a phospho lipid is going |
|
|
47:52 | range itself in such a way that uh non polar region is going to |
|
|
47:57 | excluded from the water. And then polar region is going to be included |
|
|
48:01 | the water. All right. And they'll arrange themselves and stuff. |
|
|
48:04 | you can see here uh in the picture in the here, what we've |
|
|
48:13 | is what's called a lipid bilayer. have two leaflets and in these |
|
|
48:19 | you can see, you have the heads and they're both facing in opposite |
|
|
48:22 | . One's facing water in this one's facing water in that direction. |
|
|
48:26 | the tails are hidden away from the . Now, here, that's where |
|
|
48:33 | have very few of them. And they're kind of like buffalo protecting the |
|
|
48:37 | . They all point their tails inward just have the heads outward. The |
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|
48:41 | are happy because they're in the the tails are being excluded from the |
|
|
48:45 | . And so they're happy so Are we with me any questions about |
|
|
48:52 | of this stuff? So it's all at this point, right? |
|
|
48:59 | one of the things that water can because of its polar nature because of |
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|
49:03 | hydrogen bonds that they form between them that they can actually dissociate themselves as |
|
|
49:11 | . What that means is that when is sharing this hydrogen bomb, that |
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49:17 | will sometimes get torn away and be to another molecule so that the hydrogen |
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49:25 | with it. So what you end is two ions. All right. |
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49:28 | it doesn't exist for a very long of time. It will go back |
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49:31 | the original form the two water But what this means is is that |
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49:36 | you look at pure water, it's all water molecules, you have these |
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49:40 | that can appear every now and then hydroxide, which is a water missing |
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49:45 | hydrogen So it's missing an electron and proton, it has been called |
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49:51 | All right. And then here what have is you gain that proton or |
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49:55 | , I shouldn't say an electron, it holds on the electron and it |
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49:58 | off the, the hydrogen. So ends up losing that proton and the |
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50:02 | one gains that proton. And so looks as the hydro and then of |
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50:08 | , wait a second. This is right. And so then it'll release |
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50:11 | back again. All right now, , very reversible reaction. And if |
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50:16 | look at this, you can probably and see that for every 554 million |
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50:22 | , this occurs once. So what say, why should I care about |
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50:27 | ? Well, if you actually calculated it basically, this occurs one uh |
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50:33 | occurs one in every 10 million that's really what it says. So |
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50:40 | I count up the number of molecules consider the number of moles, that's |
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50:44 | ratio right there. So it's 10 the minus seven moles that you're gonna |
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50:49 | one of those molecules. So it's , very rare. But this is |
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50:54 | gives rise to our understanding of what H is. All right, these |
|
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51:01 | because they are ions, they're positively negatively charged are highly reactive that ion |
|
|
51:06 | ? There doesn't necessarily have to react another uh hydro ion. And the |
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51:12 | ion necessarily has to with that, you have another ion around it can |
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51:18 | with that. Would you agree if another positive charge? Is there any |
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51:23 | why that ion has to be attracted to that? Or is it as |
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51:27 | as it's a positive charge, I'm to it. It kind of like |
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51:30 | think as long as it's a I'm attracted to it, the guys |
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51:34 | gonna sit there and go, I'm gonna admit to that. I know |
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51:37 | generation he knows. That's true. all a acid interface off is simply |
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51:45 | molecules that have released a proton molecules have released a hydroxide. So when |
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51:53 | think of acids and bases name an , hyd hydrochloric acid is an easy |
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51:59 | . Hydrochloric acid is even up right? Hydrochloric acid is a hydrogen |
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52:04 | . When that molecule dissociates in it's releasing a hydrogen. That's what |
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52:10 | that an acid. It's that free that's floating around. All right, |
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52:14 | get to things that are not chemicals , you know, they have another |
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52:18 | that, you know. Huh? , Hydrophor. It's too easy. |
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52:27 | on. So it must be So it's a small state hydrogen. |
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52:41 | when you go to heart dissociated that what you have you guys ever |
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52:48 | of Citric acid? Yeah, that's you find in your grape juice, |
|
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52:53 | ? And your lemon juice. And also one of the best cleansers on |
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52:56 | planet, right? All right. acid. You ever heard of acetic |
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53:03 | . Do you guys like your atomic ? Um Sour patch kids. |
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53:11 | That's acetic acid. It's pickle vinegar. That's what makes it, |
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53:17 | sugar and vinegar. That's what makes all it is. Is that whatever |
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53:21 | substance is, when it dissolves it a proton or a hydrogen ion and |
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53:29 | , anion is simply a molecule with negative. So there are little |
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53:34 | we have a dissociates to a proton chlorine or what you say is a |
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53:40 | ion and chloride and H plus is a proton, right? It's a |
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53:46 | uh element that you have lost So what you left with is there |
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53:51 | proton? So you'll hear me say very often it's a proton, |
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53:55 | The second one out there that's carbonic , carbonic acid dissociates, it gives |
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53:59 | the hydrogen and now available proton right? So simply put an acid |
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54:08 | a substance that releases that pro when goes in the water, a |
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54:15 | On the other hand, releases the group, right? O H. |
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54:19 | basically that negatively charged ion, So we've got some examples here. |
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54:26 | , if you take sodium hydroxide, sodium hydroxide put in water, sodium |
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54:32 | this way, the hydroxyl is over . That is its dissociation very, |
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54:36 | simple. But there's another type of , a base is a molecule that |
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54:42 | also accept a free proton. And what we're showing here substance with free |
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54:49 | , it gives you that structure. that a substance B is the |
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54:53 | So here we have the bicarbonate, bicarbonate plus the proton gives you carbonic |
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55:00 | . All right. So a base be one of those two things. |
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55:02 | either uh except or sorry, releases hydroxyl group or it can accept a |
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55:09 | . All right, windows in the . So when you think of an |
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55:16 | solution, all you're saying is that I look at all the molecules inside |
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55:21 | , and I'm focusing specifically on the and the hydroxyl groups because remember |
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55:26 | sorry, going in the wrong water dissociates to form those two |
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55:30 | All I got to do is count the availability of those protons and the |
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55:34 | of the hydroxyl groups, right? when I do that, if the |
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55:38 | of protons is greater than the number hydroxides, then what do I |
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55:42 | I've got an acid. But if opposite is true, the number of |
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55:47 | is greater than the number of I've got a basic solution and that's |
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55:52 | we get ph from. All we're counting up the number of |
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55:56 | the free protons that are in Now, generally speaking, if you |
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56:02 | a strong acid or a strong a they dissociate, they are irreversibly dis |
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56:09 | . In other words, you can't Humpty dumpty back together again right |
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56:14 | Is that entirely true for our Yes, you can actually glue those |
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56:20 | back together but it takes a lot energy and a lot of work and |
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56:23 | not worth the effort. All So we just say that it's |
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56:28 | right? So, hydrochloric acid, you go to the lab and you |
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56:32 | that big jug of 10 normal hydro acid that is basically H C L |
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56:39 | no water in it. But when pour that into water, what happens |
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56:44 | the hydrochloric acid dissociates. And so have a whole bunch of protons that |
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|
56:48 | free. And they're saying, what I interact with? That's your acidic |
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|
56:56 | , weak acids and weak bases. the other hand, are reversible. |
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57:00 | right, they go back and forth the two states they can accept or |
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57:05 | can uh release protons easily. That that we're looking down there at the |
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57:11 | , the hydro uh the, the acid and the bicarbonate. All |
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|
57:15 | becomes a very, very important chemical in biology. Specifically in physiology. |
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57:21 | gonna see this molecule and this reaction and over and over again, it |
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57:26 | serve you well to start looking at and saying, I've got to know |
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57:29 | now today it's not so important, as I point him out, as |
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57:33 | go forward saying, aha, he this is going to keep showing |
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57:36 | maybe it's something I should probably And what we're looking at the carbonic |
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57:41 | naturally dissociates into the proton and the or in the b carbonate But |
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|
57:48 | if the environment is right, I change the reaction so that it moves |
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57:52 | opposite direction to form carbon and All I need is some b carbonate |
|
|
57:58 | protons to do that. This is wall of text slide. And you |
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58:05 | see in the wall, I already you what is P H. It's |
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58:10 | the amount of hydrogen ions, the of protons that are available in solution |
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58:16 | to our expected amount. All there's a way to calculate it |
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|
58:20 | You're not gonna have to do math this class. So you don't need |
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58:22 | worry about basically P equal to the log of the concentration of the |
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|
58:28 | All right. And so when you're at these P value, we know |
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|
58:32 | water is 10 in the minus seventh , right? That's the concentration that |
|
|
58:36 | expect to find one of these So the negative log of 10 to |
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|
58:41 | seven is plus seven, right log 10 of 10 to minus seven would |
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|
58:51 | negative seven, then negative of negative positive. So that's where that number |
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|
58:56 | from. And so we say that's happens in a natural pure water |
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|
59:01 | So if I add in more that means that negative seven becomes uh |
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|
59:07 | , right, negative seven becomes negative and negative five, the negative |
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59:10 | the negative three, negative negative negative one, negative zero. |
|
|
59:15 | no, not 00, right? of the zero is how much come |
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59:22 | . Think about, think about 10 0 is not 0, 10 to |
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59:26 | is one. What is that telling ? It's telling you that for every |
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59:31 | molecule there's one proton, that's an ratio. That's why it would be |
|
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59:36 | very, very, very horribly right? And so what we're saying |
|
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59:42 | is that the more protons you have saying one for every 10 to the |
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59:48 | seven, I remember that's that And if I say I have one |
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59:52 | 10 to 10 to the minus that means I've increased the number of |
|
|
59:56 | . So my, my concentration gets and bigger and bigger, right? |
|
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60:01 | long as my numerator is getting the denominator is staying the same and |
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60:05 | you could just do the math and , OK, it just equals this |
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60:08 | . I know I'm confusing many of going, you're doing math and I |
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60:11 | see it. And that's, that's . Just think as I increase the |
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60:15 | of protons, my ph is getting and smaller and smaller. My ratio |
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60:20 | protons to water is getting smaller and in the other direction as I decrease |
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60:30 | number of protons per molecule of my P H is getting larger and |
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60:35 | and larger. And that's where we the value. Age zero, age |
|
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60:39 | 14. All right. What you're is that for every 10 to the |
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60:45 | 14 molecules of water, there's one and that's a lot less than what |
|
|
60:52 | . Normally. That's what P H . It's just counting up the number |
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60:56 | protons and I know there's a whole of texts up there, but that's |
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61:01 | all P H is and you should be freaked out by it. |
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61:05 | Are you guys freaked out about log ? My man in chemistry, they're |
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61:10 | beat you with a stick with All right, before I move on |
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61:22 | question about you, I understand When I was in school at your |
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61:32 | , I took a chemistry class. was my doctor bod except it was |
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61:36 | as good as Doctor Bock. And this professor did was he came in |
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61:42 | two clear solutions. Actually, it too clear solution. It was a |
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61:45 | of what he said was hydrochloric acid then a bunch of those little tiny |
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61:51 | pill looking things which is basically sodium . And what he wanted to demonstrate |
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61:55 | us was a simple neutralization reaction. he took the sodium hydroxide, dropped |
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62:01 | in the hydrochloro Chloric acid stirred it until it all dissolved away. And |
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62:06 | he showed us and then he drank . We are right. But what |
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62:12 | he do? He made salt Now still that would have made me |
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62:18 | , you know, and I'm I'm he was trusting in his abilities to |
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62:23 | sure they measured it and got the ratios. But simply what a |
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62:26 | a neutralization reaction is, is a displacement. If I take sodium um |
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62:31 | hydroxide and I put it in the , it's gonna dissociate into the sodium |
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62:35 | the hydroxide right into the hydroxy If I take hydrochloric acid and put |
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62:39 | into water, that hydrogen and that are gonna dissociate. The and the |
|
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62:45 | are going to be attracted to each . It's gonna form water, |
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|
62:49 | OK. And the sodium and they're both ions. And so they |
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|
62:53 | form those hydration shells around each other the water or they can associate towards |
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62:57 | another. I mean, they won't quite associated um like they would if |
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63:00 | were in the salt, but they're there. And once you're left with |
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63:03 | sodium chloride in water, that's an of a neutralization reaction. It's taking |
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63:08 | acid in a base and neutralizing both them forming water and a series of |
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|
63:14 | . This is uh not uncommon and trying to show how that kind of |
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63:18 | there. A buffer. It's something helps to make a, a cost |
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63:24 | P H whenever you put in an acid or an excessive base to a |
|
|
63:31 | , your bodies use buffers all the . And it's important to work at |
|
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63:40 | specific temperatures and at very specific PHS going to talk about too. So |
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|
63:46 | know it's a long way away. if you think about the digestive |
|
|
63:49 | the digestive system is a series of from your mouth to your stomach, |
|
|
63:53 | , to your small intestine that have PHS. And there are different enzymes |
|
|
63:58 | work in these specific compartments. So you were to consume a cheeseburger for |
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64:03 | compartment of your mouth is going to specifically with the enzymes that are produced |
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64:08 | the mouth to do very specific And then whatever you chewed up, |
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64:12 | sits in the stomach or it has different P H much, much lower |
|
|
64:15 | and new enzymes are gonna come in do different things. And then that |
|
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64:19 | that's uh that you've uh broken down your stomach. It's moving on a |
|
|
64:25 | with a different different environments, do thing. And if they were all |
|
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64:29 | same ph, then those different compartments never work because the enzymes that are |
|
|
64:34 | in these reactions work at very, specific. So your body has to |
|
|
64:41 | these P S and it does so these buffer systems, right? Simply |
|
|
64:46 | a buffer uh allow for a chemical to shift in the direction and maintain |
|
|
64:52 | P H, right? So it act like a buffer, can act |
|
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64:56 | a, like a base and accept proton when there are excessive protons |
|
|
65:01 | That's what I'm trying to show The P H is drop. So |
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65:04 | get excessive protons. So a weak will take those protons form a |
|
|
65:09 | weak acid. The reaction shift to right. And or if there's a |
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65:15 | of base around it where the what's going to happen is I can |
|
|
65:18 | that weak acid and it can start protons to neutralize the hydroxyl groups that |
|
|
65:24 | available and what you end up with weak base. And so when I |
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|
65:30 | you that reaction earlier that carbonic this is it right here, we |
|
|
65:34 | water, we take carbon dioxide, have an enzyme that combine them to |
|
|
65:38 | carbonic acid. This is a reversible . And we use this not only |
|
|
65:43 | the respiratory system, but we use in the, in the kidneys, |
|
|
65:46 | use it in the brain, we it all over the body. Almost |
|
|
65:49 | cell can do this with chemical And what it does is it produces |
|
|
65:54 | carbonic acid. The carbonic acid now going to be your weak acid. |
|
|
65:58 | this so to release that proton and you have the bicarbonate or if the |
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|
66:05 | of acid in or the amount of increase, then what you can do |
|
|
66:08 | you take that bicarbonate, absorb up that acid and then you make the |
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|
66:12 | acid and you can maintain the environment's and this is what buffers do. |
|
|
66:18 | so just showing you a couple of here, if I take hydrochloric acid |
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|
66:23 | dissociate and it's going to produce a bunch of protons, those protons can |
|
|
66:26 | picked up by the carbon. So can produce carbonic acid. The reaction |
|
|
66:30 | to make carbonic acid shift the other . It will still go the other |
|
|
66:35 | . But a usually a really, strong base on sodium hydroxide that's going |
|
|
66:43 | any of the hydroxyl group. You're to release protons that absorb up the |
|
|
66:48 | to make water. And now the between the sodium and the B carbonate |
|
|
66:52 | they're, they're charged by ions, can basically hang out together. And |
|
|
66:58 | how you neutralize and still maintain the because all you're doing is you're getting |
|
|
67:02 | of or adding to the system, appropriate amount of protons to keep the |
|
|
67:07 | where it's supposed to be. So become very, very important. They |
|
|
67:13 | what is a simple, simple, mass action, right? And simply |
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67:20 | the law of mass action says. addition of reactions on one side or |
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|
67:24 | reactions on one side of a reversible will give rise so that the reaction |
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|
67:29 | to bring balance back to the right? The way I like to |
|
|
67:36 | about it as I use this a lot, you guys like |
|
|
67:42 | people in the back like Oreos, steps. OK. So our example |
|
|
67:47 | is double stuffed Oreos. Hm. . Imagine you have in front of |
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|
67:51 | a plate with four double stuffed All right, the rule is you |
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|
67:58 | have as many Oreos as you but there always has to be at |
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68:02 | end of the at, at the of consumption there has to be four |
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|
68:06 | on the plate. All right, here you have a closet or |
|
|
68:11 | a pantry with infinite Oreos. It's a dream come true. So every |
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|
68:18 | I eat one Oreo off the I now have three. What do |
|
|
68:21 | have to do? I've got to and grab an Oreo and put it |
|
|
68:24 | the plate. If I eat two off the plate, I have to |
|
|
68:27 | to the pantry, grab two Oreos put them on the plate. I |
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|
68:30 | four Oreos off the plate. I to put four Oreos off the |
|
|
68:33 | If after eating too many Oreos, vomit Oreos on the plate. I |
|
|
68:36 | to take whatever I've done. As as there are four warriors on the |
|
|
68:44 | , I can balance them equal. that's what the role of the buffer |
|
|
68:48 | to do is to make sure that stays constant. That's a lot of |
|
|
68:52 | action. And I'm balancing between the that are moving on and moving |
|
|
68:59 | OK? Getting down to the home . So in the different type of |
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|
69:10 | and different types of compounds. And is just a language thing. A |
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|
69:15 | is something that is chemically pure. you're looking at a compound, every |
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69:19 | in that compound is exactly the same when you go into a laboratory and |
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|
69:25 | see a container on the shelf and says it's glucose, you can know |
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|
69:30 | for certain that everything inside that presumably someone hasn't contaminated it. Is |
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69:35 | every molecule in there is glucose, is nothing else in that container, |
|
|
69:39 | ? That would be a compound. chemically pure, right? A |
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|
69:44 | On the other hand, is a AAA taking a series of different substances |
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|
69:50 | and putting them together so that they're intermixed. Most of the stuff that |
|
|
69:55 | deal with is a mixture I am today. Lipton instant iced tea. |
|
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70:01 | instant iced tea is water plus iced mix. That means I can go |
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70:08 | there and dehydrate this and I can out water and I can pull out |
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|
70:12 | Lipton makes that fake iced tea mix be right. There's different things in |
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|
70:17 | . This would be a mixture. not a compact. All right, |
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|
70:22 | are three basic types of mixtures. have suspensions, colloids and solutions. |
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|
70:28 | here that a substance that is a , they're not chemically uh changed. |
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|
70:34 | right. When I took the I put it in there. That |
|
|
70:40 | now, hold on, right. can separate those things out by physical |
|
|
70:47 | . And that's why I say when dehydrate it, I can take the |
|
|
70:50 | out and I'm left with the the dry mix that's left there. |
|
|
70:54 | let's take a look at these basic and a suspension is heterogenous. All |
|
|
71:02 | . What does heterogenous mean containing one two things, two or more |
|
|
71:09 | right? If it's homogenous, that everything is equally mixed together. If |
|
|
71:16 | heterogenous, that means there's an uneven , right? So homo and hetero |
|
|
71:21 | that same terminology. Same versus All right. So a heterogenous mixture |
|
|
71:27 | many things in it and it's not distributed in a suspension. You have |
|
|
71:31 | large particles, nano molar. If not familiar with what a nano molar |
|
|
71:36 | , don't worry about it. It's big things. All right. And |
|
|
71:40 | order to keep your big things from out, you have to constantly mix |
|
|
71:45 | solution. You have to constantly agitate example that we're using here is |
|
|
71:50 | If I take blood out of your and put it into a tube that |
|
|
71:55 | allow it to coagulate, you will eventually that all the blood cells are |
|
|
71:59 | to float out of solution and kind sit down at the bottom of the |
|
|
72:03 | , right? You need to constantly the blood in order to ensure that |
|
|
72:07 | material is constant in constant motion. , uh suspensions are cloudy or opaque |
|
|
72:14 | nature. In other words, what do is if you take a light |
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|
72:19 | shine through the particles are so big the light on the light photons either |
|
|
72:25 | absorbed or scattered some on the other , you can't see the lights. |
|
|
72:31 | right. In this example right you can see this with milk, |
|
|
72:34 | is a different. This is a type of mixture. All right, |
|
|
72:37 | , you can see the guy is the light and on the other |
|
|
72:40 | the light's not coming through right This is a colloid. All |
|
|
72:45 | This is different, right? A bit different than your suspension. A |
|
|
72:53 | . So there's lots of different things it. They're not equally mixed |
|
|
72:58 | but the particles are much more right? And so when you have |
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|
73:02 | milk or a colloid, for I said milk, if you set |
|
|
73:06 | out, the material doesn't just float , they're too small, there's |
|
|
73:10 | there's not enough mass in them to have gravity to draw them towards. |
|
|
73:14 | they just kind of sit in they're kind of sustained. Some has |
|
|
73:21 | ability to go through a special time its called a gel transformation. And |
|
|
73:31 | , you take your, your you add your hot water. All |
|
|
73:37 | , you have your water, you it and you let it sit for |
|
|
73:39 | while. What we do is we to speed up the process. So |
|
|
73:42 | put in the refrigerator and what comes on the other side? Yummy, |
|
|
73:46 | lime goodness. Right? It It has a solid nature to |
|
|
73:51 | What started off as liquid turned into ? And if you leave the jello |
|
|
73:55 | too long on the counter, what's gonna do? It goes back the |
|
|
74:00 | direction becomes liquid. All right. that's that kind of transformation. These |
|
|
74:04 | colloids that do that. All then we have solutions. You can |
|
|
74:09 | up here the example that this book solutions. This is typically what we're |
|
|
74:17 | with when we think of these they're homogeneous. In other words, |
|
|
74:20 | everything in that solution is equally spread . So there's not like if I |
|
|
74:25 | a sample from the top of from the bottom of the. So |
|
|
74:29 | look absolutely, I and the other cases that I took samples, it |
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74:33 | not be absolutely right. So these things that are dissolved in some sort |
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74:40 | material which is referred to as So that's what's forming the solution solvent |
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74:46 | our bodies as water. Typically, we're dealing with solutions, it's watered |
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74:49 | well. All right. So the , the solute are gonna be |
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74:53 | very small, less than that you see them. So solutions are |
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75:00 | So you have no idea that there's something in there, you know, |
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75:03 | may be, they don't scatter So if you shine a light through |
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75:06 | , it's just gonna pass straight on . And again, because of the |
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75:10 | of the molecules and the atoms and materials, they're not going to settle |
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75:14 | . So typically, very transparent, mentioned the emotions already motion non polar |
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75:25 | . And so what we're actually looking here is we're actually looking at true |
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75:28 | and you can see you've heard of , that cream always rises because |
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75:34 | they are part of the same uh , but there are actually two |
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75:38 | one's primarily fat, the other is aqueous. And so when you put |
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75:42 | in a container, they separate out each other. And that's what you're |
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75:45 | at in that particular picture. Right there, I believe that was human |
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75:49 | milk. I took a picture of , I took a picture but I |
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75:53 | . All right. And then over on the right, that would be |
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75:56 | vinegar and oil. All right. what we have here, this is |
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76:01 | of a a list of like the between you can use that to kind |
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76:04 | help you out. Now, the little thing I want to do, |
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76:08 | two little slides here. It's just language thing. So very little time |
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76:13 | we look at solutions and measure it a different way depending upon what kind |
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76:16 | field you're in. Many of you are planning on going in the field |
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76:19 | medicine. So typically, what you're see is you'll see something that's gonna |
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76:24 | like mass volumes. All right. so this is gonna be the mass |
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76:27 | the solute that you have in the of solution. So it's usually M |
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76:31 | mil. So milligrams per mil, , sometimes you'll see a mass |
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76:36 | So this is gonna be like a solution. So if you've ever been |
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76:39 | the medical field, for example, . What we're referring to here is |
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76:44 | number of grams of material that are in 100 mil of solution. But |
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76:49 | you're planning on being an a molar here, what we're doing, we're |
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76:58 | about, I'm not done guys. got plenty of time to get your |
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77:03 | class per liter of solution and you determine the gram based upon the number |
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77:15 | moles, right? So one mole equal to the molecular weight, which |
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77:18 | can calculate out. And if you've done that before, you'll get to |
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77:22 | how to do that in chemistry, not gonna be doing it just to |
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77:24 | aware that it's a type of of . Whereas molity is dealing with the |
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77:29 | of moles per kilogram rather than moles liter. If you're not familiar with |
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77:34 | mole is right. It's not the furry animal, it's not that horrible |
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77:40 | on its face. It's simply a like a dozen or like a gross |
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77:44 | like a score. But it's a large number referred to as a |
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77:48 | It's 6.2 times 10 to the 23rd of whatever it is that you're looking |
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77:54 | . So a mole of students would one point or sorry, six point |
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77:57 | two times 10, 23rd, And so it basically describes the number |
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78:02 | particles found in the grams, the mass of a substance one more. |
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78:07 | this is the hard one osmos right , tell us how many particles of |
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78:20 | are going to be found in the . So, what we're concerned with |
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78:24 | is how a particular molecule dissociates. for example, if I have a |
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78:28 | of glucose, glucose, when I it in the water does not |
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78:32 | right, it doesn't dissociate, it goes into a solution. So one |
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78:36 | of glucose becomes 10 something like sodium , sodium chloride will dissociate right? |
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78:45 | every sodium chloride molecule that I have dissociates into one sodium ion and one |
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78:50 | ion. And so that becomes two , that means I have one mole |
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78:56 | sodium ion, one mole of chlorine together, that's two. And that's |
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79:00 | your osmon come from. And this important because this is what your body |
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79:05 | actually measuring. How many solutes do have in solution? It is trying |
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79:09 | maintain a constant value around 300 mils your body. That's what I want |
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79:15 | talk about today when we come back I know you're not gonna ask me |
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79:18 | . You never do. You could mean I'm here to answer your |
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79:22 | But when we come back, what gonna do is we're gonna start dealing |
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79:25 | the molecules you need to know. , you can ask questions. It's |
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79:32 | . Yes, |
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