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00:01 All right, let's see. it's actually working. Great.

00:07 see one person. Hi, there go. All right. You guys

00:12 to start your first day of That's actually your second day. But

00:15 you guys ready? You're like, don't know, just warning you guys

00:20 the front row. Uh This is . I'm Shamu. You're in the

00:24 . So, so you'll give my attention usually. Um This is uh

00:29 MP one if you don't know, don't know what's going on over in

00:32 two. Uh Here's the general gist the orientation. So, uh you

00:37 got the email, you guys watched videos, right? Did you watch

00:39 videos? Yeah. Ok. Um of the things we're gonna do today

00:43 we're going through the lectures is I kind of pause every now and then

00:47 , hey, remember that thing in lecture where I said, watch for

00:51 . Here's a transition just to make life easier. So you can kind

00:54 get a sense of what's going All right. But here's the gist

00:58 you don't know what's going on in class and that is a terrible there

01:01 a terrible burn in that uh right? I mean, you all

01:05 the yellow in the middle of Ok. That's not just my eyes

01:08 bad. Ok. Uh Anyway, uh go watch the videos,

01:14 familiarize yourself with how the uh uh websites uh kind of organized. Uh

01:19 can kind of see it's very, specific in terms of how I describe

01:22 course being done. If this is first day and you registered like yesterday

01:27 get in the class, go watch videos. Uh There's an assessment that

01:31 says, hey, did you watch videos? You understand what you're responsible

01:34 in the class, answer that it's for like two weeks and you can

01:38 it as many times you need to you get a perfect score. Uh

01:41 the idea if you don't know how study or you think, you know

01:44 to study, but you really So we basically everyone go watch a

01:48 on how to study and how to . This is for your sake.

01:51 telling you once you know how to and how to study school becomes

01:56 you work less, you learn which is really the goal,

01:59 And you get the grades that you , right? But if you think

02:02 can beat the system doing what you've doing for the last, I don't

02:06 , 18 years, you're gonna find really, really quickly that it doesn't

02:10 . It may not be this It might be in a class a

02:12 from now. So, learn how study so that you can be

02:16 I want you to achieve your How many you guys are planning on

02:19 into a career of like nursing medicine general? Yeah. Do you see

02:25 you're all here because you want to into, into a profession that is

02:30 , very restrictive in terms of the of people going into it.

02:34 Lots of people want to go few to do it. So once you

02:37 how to learn, it makes it lot easier to reach those goals.

02:41 right. So that's kind of the , uh, public service announcement.

02:45 we're gonna do today is we are jumping straight into the material that you've

02:49 read and you understand, of that coming into class re pre reading

02:54 not for you to know everything. just to give you a sense of

02:57 we're gonna go and to kind of some ideas of, oh, this

03:01 , what is he, what he's be talking about today? That's why

03:05 pre read. All right. And guarantee you over the course of your

03:08 , you're gonna get some really crappy . Hopefully, I'm not one of

03:12 . Right. Hopefully, that's a , all right. So, understanding

03:16 to find information on your own becomes , very valuable, especially in our

03:22 area that we're going into. So starting point today is really kind of

03:26 , the foundation on which everything in MP you're gonna need to know.

03:31 right. And in fact, this first unit, many of you are

03:33 be sitting there going when he's going start talking about anatomy. Because truthfully

03:38 we're gonna do is we're going to to get everybody on the same

03:41 Some of you have been exposed to at some point in your life.

03:45 you took an anatomy class in high , maybe you took this class another

03:49 at another institution or maybe from me Dr Gill and said, wait,

03:52 don't want to do it this semester you and you left. So there's

03:55 to be stuff that's familiar you. what we want to make sure is

03:59 understand, everybody understands when we go unit number two that we're all on

04:04 same page and we don't understand stuff this is the foundation, see,

04:08 is organized, scientists in general, to throw things into boxes when we

04:14 things apart. We're like, how do we understand in this

04:18 So we're going to just start throwing into boxes. And the very first

04:20 we're going to do is we're going break things down to its lowest level

04:24 build it, build it right back to its highest level. And that's

04:27 this pyramid is trying to show it's actually kind of flipped. The

04:30 should be the smallest thing and then most organized thing should get on the

04:35 , but that's not how this artist it. And so all we see

04:39 is that the basic understanding the building of anatomy starts at the chemical

04:45 If you've ever wondered why you have take chemistry. It's not because we

04:48 to torture you. It's because to biology, you need to understand

04:54 Now, we're not asking you to and become analytical chemists, right?

05:00 chemistry. And you're gonna hear me on the chemists over and over in

05:03 class because they deserve it, But what you're going to find out

05:08 that like organic chemistry, if you have to take it is really a

05:11 class so that you can just understand names of chemicals. All right,

05:15 doesn't feel like it when you're taking . But when you have like five

05:18 past, you're like, oh, I understand. And so what we're

05:23 to be looking at first in this is just some basic biomolecules because you

05:27 those biomolecules to start building the very smallest level of life, which

05:33 called the cell. And so we're to look at the cell too.

05:36 in fact, in this lecture, going to kind of just do the

05:40 overview of many of these structures. we go from biomolecules. Biomolecules are

05:45 the legos that build cells. And what we're going to do is we're

05:48 to take cells of which there are types, there's about 300 different types

05:52 cells in your body that we've And as we get better and better

05:56 identifying the molecular level of things, start realizing that there's actually more cells

06:01 that. All right, just to you an example that you don't need

06:04 know. But like, so I've in a department of immunology. That's

06:08 my background. It just happens to where my phd happened to come

06:12 I'm a reproductive biologist. It's really . So I'm not gonna try to

06:17 it. All right. But like big picture in immunology is like,

06:21 have T cells and there are helper cells and there are cytotoxic T cells

06:25 it's just one type of cell, T cell. All right. So

06:29 a couple of years ago, I like, trying to prepare a lecture

06:32 T cells for A MP two and looked up T cells just to make

06:36 I understood there are 40 different types T cells now. And it's because

06:41 gotten better at finding out what's unique each of these. All right.

06:45 we're going to understand basically what are biomolecules that make cells and we're going

06:49 take cells which are the basic building of life and we're going to build

06:55 from that. And then tissues are just taking like cells, cells that

07:00 similar to each other and creating larger . And then we have four basic

07:05 of these. We're going to use four basic types of tissues and we're

07:09 to build organs. Now, organs probably what you're thinking of.

07:13 hey, I'm taking anatomy class, going to learn about these organs and

07:15 like, yes you are. But need to understand the tissues and the

07:19 that are involved in those tissues. understand why that organ is doing the

07:23 that it is, why is a , a heart and why is the

07:26 , a stomach? Right? So why we have to understand these lower

07:30 . And then what we're going to is we're going to take organs and

07:33 organs that are involved in the same are kind of mashed together to produce

07:38 organ systems. Now, an example an organ system that you're already familiar

07:42 is the digestive system, right? heard of the digestive system, you

07:46 what are some structures in the digestive ? Colon? Oh Wow. We're

07:50 deep here. We got a I was going like stomach. That's

07:54 the easy one. But it starts your mouth, right? You've got

07:57 mouth and you've got your esophagus, teeth and your tongue are part of

08:00 digestive system. You've got your small , the large intestine which consists of

08:05 colon. So that's kind of dividing up. And there's parts here throughout

08:10 all work together to turn a cheeseburger the small little pieces, parts that

08:15 body actually wants the mo the biomolecules that it can provide energy and building

08:22 for your body to survive. And anything it doesn't want that digestive system

08:26 going to get rid of stuff. so starting with that cheeseburger to poop

08:31 all the stuff in between is being by organs that are working together to

08:35 the job done. Right. So can start seeing, we're getting more

08:39 more complicated as we go along. it's very easy for us because we

08:44 at biomolecules and go, oh, are scary and complicated. They're

08:48 But what we're doing is we're taking things and making things much, much

08:52 complicated. And then with an organ , what you're going to do is

08:57 where you get your organism. And this class is focused on humans.

09:00 right. It's human anatomy and And so what we're going to be

09:04 is we're going to be looking at structures that ultimately give rise to these

09:09 that give rise to you. That's big gist of the class. And

09:14 course, the class is broken up two semesters. So this is A

09:17 P one and it's the least interesting the two. I apologize. That's

09:22 the nature of the class. It matter where you take it. All

09:25 . So we'll work here working on very specific things. We're going to

09:29 at the skin, we're going to looking at the musculoskeletal system, we're

09:32 be looking at the nervous system and when you go and take a and

09:36 , that's when you do all the that's probably interested you or made you

09:40 in the subject matter in the first . We're gonna deal with the heart

09:44 the kidneys and the respiratory system. we're gonna be dealing with the digestive

09:48 and the reproductive system, you and the endocrine system, these are

09:52 ones I can think of off the of my head. All right.

09:55 that's a MP one and a MP in a nutshell. We're looking at

09:58 organism that is uh formed by these which are made by organs, organs

10:05 constructed from tissues, tissues, from and then cells from the biomolecules.

10:12 all those first couple levels through the , what we're going to be kind

10:15 doing in this first unit? why are living things, living

10:21 What are these organ systems doing? it basically boils down to these four

10:26 right now. Again, this is simplified version, right? What are

10:32 doing? Well, we are making and we're consuming energy, right?

10:36 those are kind of the big So this allows us to do

10:41 All right. That's the simple way think about it. So, what

10:44 describing here in a fancy word is metabolism, right? Metabolism isn't the

10:50 where it's like, oh, I eat more or less and not gain

10:53 , you know, or gain That's not what it is,

10:57 it can apply to that. But what metabolism is, is the sum

11:02 all the chemical reactions that are taking in your body. All right.

11:07 here's that whole chemistry thing again. chemistry just keep popping its ugly head

11:12 . All right. Now we have term, there's two different types of

11:16 in a very generic sense. We an opportunity to build stuff and we

11:21 an opportunity to break things. All , when I'm building things, the

11:25 of metabolism that I'm using is called natural. All right, then when

11:30 breaking things down, that's catabolism. there are kind of two terms that

11:34 should kind of be familiar with and easy way to remember this is think

11:37 people who use steroids like to build muscle, right? They use anabolic

11:43 . So there is the term anabolic from anabolism, I'm building muscle.

11:48 right. So that's the first thing living things do is that they produce

11:54 and they consume it. The second they do is they grow and

11:58 So these two things are kind of together because growth and repair kind of

12:01 similar mechanisms. So like if your has broken something, it's going to

12:06 the same mechanisms it uses to build up. All right. Now,

12:11 we talk about growth, what we're is we're, we're going to either

12:15 in size or what we can do we can say we're increasing in

12:20 All right. So we'll see here just a moment when cells, when

12:24 life began. All right. So dad's sperm and your mom egg came

12:29 and created a individual new cell and new cell started off dividing and all

12:35 cells that were, there were all same and then almost within a couple

12:40 divisions, about four or five some of those cells started differentiating and

12:46 , right? So that's how quickly happens, you know, but the

12:50 here is that this growth process results a specialization as well. We are

12:57 organisms. The reason my kidney is than my stomach, which is different

13:01 my heart is because of the All right. So that's a characteristic

13:06 living things have even single cell organisms that ability to grow. And then

13:12 they have damage occur to them, can repair it. So the damage

13:15 , we're talking about malfunctioning cells, ? So, pathogens pathology is when

13:22 aren't doing what they supposed to do we repair though, that's what our

13:27 system is responsible. For as an , the other thing is we are

13:33 . If anything in the last couple days have told us that the environment

13:38 us changes a lot. Right. we were in our twenties a couple

13:43 days ago today, we're in our tomorrow. It should be in the

13:48 and then it drops back down into thirties again. Yay weather,

13:54 But the truth is, is what we do? We adapt to our

13:59 , we adapt to the food that us, we adapt to pressure and

14:05 and stuff that adaptability is something living do, nonliving things can adapt.

14:11 just are all right. So that is the ability to sense what's going

14:18 around us. So the change in environment and not just like the

14:22 I mean, that can be both and external. So change that

14:26 we adjust and modify the activity of cells and tissues and organs to respond

14:32 that change. And the term stimuli to the change. So if you

14:36 up and you look at these it was a little brighter than looking

14:39 at me, right? And so eyes adjusted to the brightness of the

14:44 , that would be an adaptation, other type. And we're gonna try

14:47 get to this at the end of class is homeostasis. Homeostasis is simply

14:51 ability of an organism to maintain a internal environment. Despite the fact that

14:57 environment is changing around them. again, that change, when we

15:01 environment can be both internal or And again, temperature is the easy

15:05 to look at. It might have 20 degrees. Right. But your

15:10 body temperature was still 98.6 degrees. . Now, how did you maintain

15:16 if you went outside with a what did you start doing? Started

15:21 . Right. You started producing more , right? And then you went

15:25 and blasted the furnace up to about degrees so that you'd warm up and

15:28 you started sweating, right? So that adaptation or adaptation with regards to

15:37 . The last thing is reproduction. right. So reproduction here refers to

15:41 of two things. It can refer replication of cells for the process of

15:46 and development. So think about what were uh probably in sixth grade.

15:51 just about to start puberty, You went off in, in the

15:54 , came back and for the your voices, well, sixth

15:58 nothing happened. Sorry about eighth That's when your voice has changed,

16:03 ? But girls, you went off then you came back in seventh grade

16:07 you all of a sudden had shape parts that guys didn't understand and it

16:12 very confusing time for everybody. All , you grew from someone who was

16:16 this tall, to a person that about this tall. I love to

16:20 the story of my best friend who a big giant blueberry of a

16:24 All right. So can you picture blueberry person? Nice and round and

16:28 not exaggerating. He really was. put him on his side and you

16:30 roll him? All right, he off to summer camp, came

16:35 He said, hey, Doctor because that's what he called me.

16:37 , Doctor Wayne, how you Good to see you. And I

16:40 at him, I'm like, who you? He had actually gone through

16:45 proper puberty where literally he went from to carrot, right? So that's

16:50 proper male form, you know, hair, big up top, big

16:55 walking around. I mean, iii was totally blown away. All

16:59 So again, why does this Well, because we replicate ourselves to

17:06 bigger and multiply and divide or multiply become more specialized? That'd be the

17:12 level and that's occur in terms of . Do you need something a little

17:16 easier to remember? Instead of Think about when you go out and

17:19 sunburned or just um you know, outside, you have your layers of

17:24 , right? And they peel off a sunburn. So your skin is

17:28 replicating. So the dust that you in, this is me grossing you

17:32 out is all the dead skin cells have sloughed off our bodies.

17:37 All right. And then the other is the fun Bauchi a bow.

17:40 . Type of reproduction where we take and they make new organisms.

17:44 That's where my specialty is both in degree and in my family, I

17:49 four kids. Ok. And it's more fun because I'm just gonna tell

17:55 now because I'll refer to it I have two sets of twins.

17:58 , yeah. And my wife was twin and her sister who's not her

18:02 also had twins. So it is of those fun little run in the

18:05 things. Ok. So these are things that living things do. So

18:09 just gonna give you an example of thing that is not a living thing

18:11 we think is a living thing. do not count as living things.

18:16 right, they are incapable of reproducing reproducing themselves. They are dependent upon

18:22 host organism to allow them to overtake machinery and produce those viruses. Viruses

18:29 incapable of reproducing on their own, is kind of cool. But they

18:33 able to do a bunch of those different things. All right. So

18:38 we skip over biomolecules. Why? chemistry is boring and we'll come back

18:42 it and give it a whole lecture its own. Ok. So this

18:45 again, us just running through Notice here, what am I doing

18:49 I'm transitioning from an intro to a , right? Remember. And so

18:54 why I'm saying when you're listening to talk, whether it's me or somebody

18:57 , listen for transitions, watch for that will tell you a new idea

19:01 a new topic. This might be that's important. Not necessarily always going

19:06 be important, but sometimes it All right. So cells are the

19:10 unit of life. It is the level of life. So, whether

19:14 a multicellular organism or a single cellular , this is the lego or the

19:19 block of life. All right. in this picture, what we're looking

19:23 is a cell from a eukaryote. would be something like us. We

19:28 multicellular, multicellular eukaryotes. So we a unique style of cell, whereas

19:35 have prokaryotes, this would be a cellular organism. You do not need

19:39 be able to distinguish them. I'm asking you to know the difference between

19:42 and just trying to show you it matter if you are a single cell

19:46 multi cell, you have a lot the ve very similar things. All

19:50 . So we're focused over here. right. So this is a generic

19:56 that says all cells contain these certain , which we'll go to in another

20:01 . All right. So here inside cell, we have all the machinery

20:05 need to maintain homeostasis. All So homeostasis you're going to see is

20:11 major theme in physiology. So remember class is anatomy and physiology. Anatomy

20:17 structure physiology is function. So when talking about how organs and tissues

20:25 we're really kind of coming right down this and saying, what's going on

20:29 at the level of the cell, are three basic shared components of all

20:34 cells in your body. They have membrane. So that's basically the,

20:40 structure that defines the outside of the . It's what separates the inside machinery

20:46 the outside stuff. All right. what we've done is we've, we've

20:51 a unique compartment. So this is the cell becomes a unit of

20:55 Think about your own home. All . Is your bedroom separate from the

21:01 , is it? Yeah. So in the kitchen, do you

21:05 in the kitchen? No, not purpose, at least. Right.

21:10 you cook in the bedroom? Please that in the way that I mean

21:15 OK. No, you don't cook the bedroom, right? You have

21:21 an environment that's unique for a right? In each of those particular

21:28 , right? And so that membrane like the walls to your bedroom and

21:32 walls to the kitchen, it separates two spaces from each other so that

21:36 can have unique activity taking place All right, all cells have genetic

21:43 in them. All right, doesn't use all that genetic material, but

21:48 cell in your body and I'm going say this, even though there are

21:52 that you don't need to know about cell in your body shares the same

21:56 material. It has all the same . So, if I go inside

21:59 cell that's inside the heart versus a that's inside the skin, I would

22:04 your entire genome in each of those cases. All right, clearly the

22:10 and the, and the skin do different things. Would you agree with

22:12 on that? Yeah. But all instructions to tell that cell what to

22:16 are found within your genome. And each cell has the genetic material to

22:22 an entirely new cell. All And then the other thing that all

22:27 have is it has the go in all the organelles and mater and the

22:33 and all the machinery is going to found. All right, we just

22:36 that the cytosol fluid. So it's plus stuff. We're not going to

22:40 about the stuff today. All we'll get to the stuff in a

22:43 of days. All right. So fluid, genetic material and a

22:48 Now I'm just going to sneak over to the Pro Kario just to show

22:52 that it has all the same All right. So all cells have

22:55 , all your cells have these, we can go look at the bacterium

23:01 , right? And say, do you have all those same

23:04 Are you a cell? Do you this? And it's like,

23:06 so see I have my nuclear this yellow space here with all the

23:10 , pretty little dots in it. side is all that is the same

23:14 that you see over here that has the little stuff in it. And

23:17 of course, there is a membrane is the dark purple structure. I

23:23 that's purple. I can't really Um, not all the stuff on

23:26 outside. All right. So you see it doesn't matter if you're a

23:30 cart or you car out a you have the same stuff. All

23:34 . Now, what's unique once you getting into the eukaryotes and, and

23:39 just going to use humans as the , you'll have other stuff. So

23:42 can see in here we got these , these are what we, you'll

23:45 the term membrane bound organelles, there'll other types of structures found as

23:50 And then the unique thing is something refer to already is that in a

23:57 cell, for example, versus a cell, even though they have the

24:01 same genetic material, there is regulation the gene level that makes sure that

24:07 genes that make that skin cell be skin cell are turned on and

24:11 the machinery to turn it into a cell are turned off. Whereas over

24:15 in the heart cell, what you is all the machinery that allows it

24:19 be a heart cell turned on and the machinery that allows it to be

24:22 else are turned off. Ok. even though they have all the

24:27 all the code to make things specific things are being turned on and

24:32 in your prokaryote. That's your organism well as your cell. So basically

24:38 whole whole genome is, is All right. So I've already alluded

24:43 this or I've already said this is you started off life as a single

24:48 , you, one cell turned into cells, two cells turned into

24:51 turned into 88 turned into. And is where it gets weird 12 or

24:56 somewhere in there. That's where the starts happening. And what we're talking

25:01 here is this differentiation process. And this is just a real simple model

25:05 kind of show you it is hey, your muscle cells and all

25:08 other cells in your body all come the same source. And what we

25:12 to is the source cell is what refer to as a stem cell.

25:17 if you hear stem cell research, they're saying is what we're trying to

25:20 is we're trying to get a cell to its very basic starting block.

25:24 then we want to be able to it and differentiate it into the direction

25:28 want it to go. One of 300 plus different types of cells that

25:32 found in the body. All Now, typically what we say is

25:38 this process of differentiation, to get unique characteristics, to make all these

25:44 types of unique cells is irreversible, is why stem cell research is such

25:49 big deal is because people are desperately to figure out how do I go

25:53 ? Right. This would be akin saying I've gone through college and gotten

25:57 degree. Now, I wanna go the way back to kindergarten and start

26:00 over again. How does that All right. Now, there are

26:04 that work and there are different systems are functional, but we haven't really

26:09 it out perfectly just yet because the does appear to be irreversible. All

26:14 , doesn't mean that it won't It just means we haven't figured it

26:17 entirely. All right. So what say is that very early on in

26:22 when you're in those really early stages that the individual cells can be

26:28 All right, what we say is totipotent toti total potent mean the ability

26:33 become anything. So you can imagine , I've got my single cell,

26:37 divides into two divides into four. I can tease those four cells

26:42 they're still in that totipotent stage and can keep going if you've seen identical

26:47 , that's what happened at some those cells very early on divided apart

26:52 they are basically clones of each And you can actually replicate that process

26:57 many times as you want to in laboratory, not in real life because

27:00 wants to give birth to like six that are all identical? No

27:03 OK. Um But the idea is I tease them apart early enough,

27:08 still at that totipotent stage where they differentiate into everything in their own unique

27:14 . All right. So as the are beginning to form during embryogenesis,

27:20 the process of development, that's when start differentiating, becoming really, really

27:25 . Just as an aside, for , the stem cell that gives rise

27:31 your muscle cell also gives rise This is so sad to say your

27:35 cells, all you have to do turn on a specific gene and it

27:40 one direction or the other. Which do we want it to go

27:45 right? But your body also needs . We'll learn that a little bit

27:49 . All right. So this differentiation is what gives rise to the specialty

27:57 of the cells. So that when become tissues, they're able to do

28:01 specialized functions of those particular tissues. right. So cells become tissues and

28:09 said a tissue is simply a group cells of like function. So they've

28:14 through the differentiation process, they're hanging together, they're creating these larger

28:19 And what we're gonna do is we're to use them to create a common

28:23 for a larger structure. There are basic types of tissues, we have

28:29 , connective tissue, muscle tissue, tissue. All right. And how

28:35 approach this in the class. it's you're going to feel like

28:38 we stop and start a lot. like this class is like the latter

28:44 units. So if there were four , the latter two units is focused

28:47 solely on the nervous system. So we talk about nervous tissue, we

28:53 spend like a day talking about nervous . And then we spend a lot

28:56 time talking about what it does. right, when we talk about the

29:00 , we have like we're talking about , that's like one day. So

29:04 you're gonna see, feel like these things are weighted really differently,

29:08 in a very generic sense. And is what we're kind of focusing on

29:11 . Generally speaking, what do these tissues do? Well, epithelium for

29:16 most part covers stuff, connective tissue the most part supports things. All

29:22 , it's like a glue, all , nervous tissue. What does it

29:25 ? Well, it plays an important in controlling things in the body and

29:29 muscle, what does it do? , it promotes movement, right?

29:32 just locomotion, but just movement in body. And when you look at

29:36 organ system, what you'll find is generally speaking, they'll take all four

29:40 these different types of tissue types and them in different concentrations, different

29:46 So that that tissue can do something . All right. Or the,

29:50 organ can do something unique. there are cases where you won't

29:54 like in the brain, there is muscle. All right. And that's

29:58 that you don't have to have all , but generally speaking, you'll see

30:02 four. All right. So we're kind of go a little bit deeper

30:06 to kind of paint the picture. then, uh, in a couple

30:10 lectures, when we come back to , we're gonna go a lot

30:13 All right. So this is us the toe in the pool. All

30:17 . So we're gonna go over uh, these very, very

30:21 So, epithelial tissues or epithelium is term we use. Can I time

30:27 for a second? Because I just about that. I know I talk

30:30 . If there is a question, be afraid to stop me. It

30:34 is the best way to put the on my mouth. So I cut

30:37 . He's talking so much. I'm ask a question. That's, that's

30:40 fine. I'm not gonna be offended . I'm not expecting you to walk

30:44 of here with 100% knowledge, you , or understanding you should be able

30:48 stop me and ask questions. Is ok? I know it's scary to

30:52 professor questions in a class of 400 . I'm stupid. I don't know

30:56 going on. Trust me. If don't know, there's at least,

31:00 know, 40 other people who don't . Ok. That's perfectly fine to

31:04 . All right. And if you it all, you wouldn't have to

31:06 the class. So, there you . All right. So, what

31:10 they have here? Well, we're primarily about sheets. If it's a

31:14 system, we're dealing with sheets of . All right. And what these

31:18 is they're going to cover the surface your body. So when we talk

31:21 integument, integument is the fancy word saying skin. So you can

31:25 oh, when I look at my , I'm looking at epithelial cells,

31:28 pretty easy. But when I look organs, typically they're gonna cover the

31:35 and the inside of your organs. right. So a blood vessel,

31:39 example, the inside tube that is . All right. So they're covering

31:46 a tissue. Typically. What they're do when you see eithe is they're

31:50 provide uh secretions and they're gonna, have the ability to absorb material.

31:56 right. Now, again, it's be uh depending on where you

31:59 I'm just gonna use the skin because easy. I mean, think about

32:02 is something you secrete on the surface your skin? Sweat. That's a

32:06 one. How it up on your . What do you got there?

32:09 the nasty greasy stuff. Yeah. there, there's some real simple examples

32:13 secretion. All right. And then . If you've ever taken lotion and

32:18 it on your skin. It's not sitting on the surface of the

32:20 What happens? The skin absorbs right? So this is an example

32:25 the two abilities that epithelium can And there are better examples of

32:31 But I think for our purposes right , that's good enough. All

32:35 The other thing that they do is they exhibit unique polarity. Now,

32:40 you hear polarity, you probably think , right? Like oh there's positive

32:44 negative charges and that's not what this . It means they have different or

32:49 sides to them. All right, gonna use a model of a human

32:53 demonstrate polarity. If I were to me in half from top to

32:58 would my left side look exactly like right side? I mean, if

33:02 just look at me just am am a mere image from left to

33:05 Yeah, kind of sort of OK. So I don't have polarity

33:10 , right? But if I cut in half this way, does my

33:13 look like my bottom? No, different. That's polarity. And this

33:19 is expressed in epithelial cells because if facing outward to the surface, I

33:24 to be able to secrete things or things through there. And then on

33:28 bottom side, I need to connect something and allow materials to move into

33:33 out of the body. So those sides have to be different from each

33:38 . And that's what the polarity refers is the difference in the stuff on

33:42 surface side versus the difference of the of the body facing side. All

33:48 . So the structure facing the surface what is referred to as the apical

33:53 . Or if you're thinking of like , like a digestive tract or a

33:56 vessel, when you make a tube inside of the tube portion, this

34:02 right here, that's referred to as lumen. Ok. So if I'm

34:07 outward, that's apical or if I'm the inside of the tube, that

34:11 apical. All right. And then other side is collectively referred to as

34:15 basal lateral side, basal from base lateral for the sides. So here

34:22 the basal lateral. So basal is here, lateral there jam together you

34:28 a new word, basal lateral. right. So you can see

34:32 does the apical look different than the lateral side in the picture is one

34:37 and has like little tiny fingers or , you know? All right.

34:42 the reason for that is to create surface area. So I can create

34:45 absorb down here. I'm connected to . What do you think I'm connected

34:49 ? What does the picture tell What am I connected to connective

34:53 Do you see how language comes? right, connected to connective? All

34:59 . So there's your epithelium muscle we'll to when we talk about the uh

35:04 and typically when we talk about the , we really talk about one of

35:07 three types. All right. So gonna primarily talk about skeletal, but

35:11 are three different types of muscles. cartoon show you structurally they're very,

35:15 different from each other. All they're job is to create one of

35:19 types of movements, locomotion, which you moving your body around or they'll

35:25 materials through the body. So for , the heart is made up of

35:30 . It's called cardiac muscle. Is heart moving you around the room.

35:35 . What is it? Moving it's pumping, it's acting as a

35:39 . So it moves fluid through your . All right. So notice motion

35:44 have to be locomotion. All So because it re uh uh deals

35:49 a lot of, of action, lot of activity. It's going to

35:53 highly vascularized. It needs to have fuel and the oxygen to allow it

35:57 do the job that it does. right. So you'll see that muscle

36:01 is very, very uh bloody. right. A lot of vasculature.

36:06 right. The three types we have muscle. This is voluntary. It

36:11 one that plays a role in locomotion we say voluntary. What does that

36:15 ? It means you control it. wave at me. Hi. Uh

36:19 , see you all chose and then are the people who are too cool

36:22 school, who are like, you make me do that, you

36:24 So that's voluntary. You have control that. So skeletal muscle, you

36:31 cardiac muscle. On the other and smooth muscle are involuntary muscles.

36:36 slow down your heart can you, can't do it right now. Your

36:42 can respond in terms of the number contractions based on uh you know,

36:48 interaction with your environment, but you no control to make it speed up

36:52 slow down. All right, we're put you in an embarrassing situation.

36:55 of that cute guy or that cute that you're really, really interested.

36:58 they come up to you and hey, how you doing? What

37:00 your heart do? It starts beating fast, doesn't it? Right.

37:05 you're sitting there trying desperately to will to shut up and stay in your

37:09 because please don't let this person know I like them, right? You

37:14 make it slow down. It's just to all the feelings that you

37:18 All right now, cardiac muscle is to the heart. All right.

37:23 looks a lot like uh skeletal but it's not, it's very different

37:28 then smooth muscle while it's an involuntary , it's very, very different in

37:32 and it's going to be found in hollow organs. So a hollow organ

37:36 simply anything that has a space in . So like the digestive system,

37:40 organs, respiratory system, cardiac these are all hollow organs, renal

37:45 . We'll get into them as we along. But basically anything that has

37:48 tube that's associated with it, that's hollow organ, nervous tissue. Uh

37:54 are more than two types, but kind of focus in on the two

37:58 cell types. The first is the . The neuron is the exciting one

38:02 that's the one that sends electrical signals allows your body to um respond to

38:09 . All right. So this is responsible for long distance communication is the

38:14 we kind of think of it. right. So how does it

38:18 Well, you're gonna send it it's gonna process information, then it's

38:22 send a signal that's the gist of and we will spend plenty of time

38:25 about them. Uh That's good So the other type of cell are

38:30 glial cells. Glial literally means So these are the cells that act

38:35 connective tissue in the nervous system, they're not connective tissue, they actually

38:42 multiple functions and they are neural in . In other words, they are

38:47 nervous tissue. All right. how do we distinguish glial cells from

38:53 ? Glial cells don't transmit information. are the support cell neurons transmit and

39:00 the last type of tissue um that dealing with here is connective tissue.

39:04 this is a really truncated version because a lot of different types. And

39:07 just tried to throw two up here to show you how diverse connective tissue

39:13 be. All right. So, my slide, you'll usually see me

39:16 connective tissue as CT because I'm Um It's just whenever you see CT

39:22 think connective tissue. All right. , their job. Connective tissue,

39:26 says the name, it connects So it's a support tissue. It

39:30 you to build structure. All So that's kind of the big

39:35 Your cartilage in your body is connective . Bone is connective tissue. All

39:39 . The things on which the epithelium is connective tissue. And then you

39:44 things like blood and it's like what blood is a connective tissue.

39:48 And the reason blood is a connective is because if you look at the

39:51 of all the connective tissues, they from the same location. All

39:55 So embryonal embryo uh embryonic, they related to one another. All

40:02 So what we do is we basically at what are the cell types that

40:05 found in the connective tissue? What of fibers are found in there?

40:09 is the stuff in between everything? is the matrix? And then that's

40:14 we classify connective tissues. All And it's ultimately that matrix that defines

40:20 function of the connective tissue. So can kind of see here. This

40:23 just the general overview we will go all the big families of connective

40:29 And what we're going to do is going to take each of these

40:31 And what we're going to do is can make organs out of them.

40:34 right. So you can see, have two or more tissues. So

40:37 you have one type of tissue, don't have an organ yet, you

40:39 to have at least two of these make an organ. And what we're

40:42 at in this picture here is your . So you can see here's my

40:46 and I'm looking at the internal uh of that stomach and it's not for

40:52 to memorize, please. I'm just to point out this is where you

40:55 see all four of those tissues. you can see out here the,

40:59 pink part right here. That's The yellow part everywhere you look that

41:04 connective tissue you see here and all stuff down there that's I'm gonna call

41:11 orange to look orange. Yeah. . OK. OK. OK.

41:16 you say ochre? Oh OK. . You're in big trouble.

41:20 But this stuff down here that's, muscle. All right. So that's

41:24 of them. And the one thing don't see in the picture, the

41:27 didn't draw it because it'd be too are the nerves, but there are

41:31 associated with this layer. There are associated with that layer. And so

41:36 essence, it's there, we just have it in the picture. And

41:41 how these things are related to each . The concentrations of these particular tissues

41:47 their arrangements give rise to the unique of the stomach, which is responsible

41:52 protein digestion specifically in the digestive All right, it's different than the

41:59 intestine and it's different than the large and it is different than the esophagus

42:04 the mouth. Now, all those still have tissues, all four of

42:10 , but they're structurally very different. , what do we get out of

42:16 ? What did we say? What next? You guys remember?

42:20 Good. Thank you. Paying So now we're gonna look at systems

42:25 part of me showing you this slide to show you that you're walking into

42:28 class with some walking around knowledge. right. So you may not call

42:33 these things, but you're familiar with . So these are the three systems

42:37 gonna talk about in this class. have the integument, that's your

42:41 your hair, your nails and sweat and your oil glands. All

42:44 And their job functionally speaking is to your body. All right, they

42:51 as the barrier between the external environment the internal environment. That is our

42:57 here. It regulates body temperature. right. So that would be the

43:03 , then we move down to the system. All right. So this

43:06 thing right here is trying to show nervous system. And again, it's

43:09 a great picture, but here we're with the brain and the spinal cord

43:13 all the nerves in the body. so what we're dealing with here is

43:18 in data or input from our processing that information or sending it up

43:25 the nervous central nervous system, processing and then responding to that. If

43:29 ever touched something hot, right? a stove, please don't do

43:33 Or if you're like my eldest son he was two years old, goes

43:37 to a metal slide in the middle a Houston summer and puts both hands

43:42 the slide. What did, what he do? Burned his hands and

43:46 moved it away, right. So would be detecting stimulus, right?

43:52 stimulus, responding to the stimulus, the hands away and then the musculoskeletal

43:58 , that's just a fancy way for two systems that are unique, but

44:02 work together for a common purpose. so this is your bones,

44:07 The skeletal muscle and then the things connect them. And so you can

44:11 of see all the connective tissue, cartilage, the tendons and whatnot.

44:15 that's job. The musculoskeletal system together movement. Well, partly it also

44:23 an important role in supporting and The only thing protecting your digestive

44:28 your abdomen are the muscles of the , right? But up here we

44:34 bone. All right. I got bone sitting right here in the middle

44:38 my chest. What's it? Protecting heart? But it won't protect a

44:43 heart. I'm sorry. That's the joke of the day, I

44:48 All right. So basically, it al it plays an important role

44:52 protection. It also plays a important in producing the blood cells and the

44:59 cells are part of connective tissue. it's kind of this larger structure and

45:05 gonna be taking place inside the And when we get to the

45:07 we'll talk about that. All But you can see these systems are

45:11 just limited to, to like the little thing, they have usually multiple

45:16 in that. And then in A P two, you'll cover all these

45:20 like for example, a respiratory which is your nasal passage and trachea

45:23 lungs and some other structures. And allows you to move air in and

45:28 of the of the lungs. And what you're doing is you're bringing air

45:32 specifically oxygen near to the blood So that, that oxygen can be

45:38 throughout your body because all your cells oxygen, even the little cells in

45:43 little toe. And so it's going get a lot faster if we can

45:47 that oxygen not passing through the which it does just really, really

45:52 and very slowly. If we breathe in and out, we can bring

45:55 right up next to the blood which then allows us to deliver it

45:59 far in distant places in the Cardiovascular system is your heart, your

46:03 vessels and the blood, what we're here. Well, we are moving

46:09 , including gasses, but nutrients and throughout the body. So your cells

46:14 the fuels and the oxygen and they're produce the process waste. And so

46:18 we doing is we're using the blood and the blood as the means to

46:22 this material around. And the force we're creating is through the heart.

46:26 then what we're going to do is going to get rid of the waste

46:28 we're going to use up the fuel the oxygen by those cells. And

46:33 the goal of the cardiovascular system in nutshell. We have the immune system

46:38 the lymphatic system, which is what that's supposed to be representing right

46:42 This is what's protecting you against right? Um It also allows you

46:49 uh uh collect things that shouldn't be from the blood to be returned back

46:54 the blood again. Now you'll get that a little bit later. Um

46:58 structurally, we have lymphoid tissue. , think of your tonsils, uh

47:04 . If you've heard of that, , you may have heard of lymph

47:07 and then the immunocyte are the, immune cells and there are lots of

47:12 endocrine system is not really a system all, it's just a bunch of

47:16 structures in the body that all collectively , um, hormone secretion.

47:24 that's its functionality, right? And the, the, there are parts

47:29 the brain that are similar to parts the, uh, uh I'm just

47:33 use the gonads down here. The . They, they're, the similarity

47:37 that they produce hormones and they govern your body behaves and how you respond

47:42 your environment. So it's like the system, but it does. So

47:46 chemical, it communicates through chemicals as to electrical signals. All right.

47:51 so there are a lot of different , but we're not gonna go through

47:54 all in terms of what they control , metabolism, reproduction. So all

48:00 fun stuff. And then finally, have the urinary system, urinary

48:05 kidneys down to the bladder. And , the urethra, what we're doing

48:10 is we're taking blood, we're processing blood, taking out the things the

48:13 doesn't want and removing them from the . So we call it blood conditioning

48:18 the term that we use with regard the digestive system. Here's your digestive

48:24 starts with the mouth ends with the . It's one big long tube with

48:27 areas that do different things. But , what you're doing is you're taking

48:32 , you're breaking it down, you're the materials that you want to keep

48:36 you're allowing the remaining material to be . And lastly, we have two

48:42 system, one reproductive system for the , one reproductive system for the

48:47 All right, represented by these two . All right. So here these

48:51 the structures again, I don't want go through them all. But their

48:54 is to produce the gametes, uh steroids. So they serve as part

48:58 the endocrine system. And then what we're doing is we're bringing those

49:03 tog together so that we can create organisms. So that's your body in

49:09 nutshell, right? Those nine systems 9123, someone probably go back and

49:15 them. I think it's nine, might be 12. I don't

49:17 Um those systems make you all And so it's important to be familiar

49:25 aware of those structures even though we're focusing on those three. Now,

49:34 you've taken science classes, you probably I should ask. Are there any

49:39 at this point? Does this all pretty straightforward? Do I follow the

49:43 a lot? Yeah. All If you've taken a science class

49:48 you've probably noticed that it has its language, especially those damn chemists.

49:52 mean, when you got that three five dash, you know, in

49:57 , da da, da da And you're just like, can you

49:59 English? No, because chemists need have a specific language to describe stuff

50:06 this is true in anatomy as So I want you to go back

50:10 time, we're gonna go back about 100 years ago. It's taboo to

50:16 a human body. All right. is, it is wrong because the

50:22 is a, a sacred thing, ? And so if you go and

50:28 cutting open a body, you are desecrating something that is good. That's

50:33 idea. All right. But during age of enlightenment, people,

50:37 I wonder how this body works. wonder what's going on. You

50:41 where do babies come from? You , let's start digging around. We'll

50:45 find corpses because people die all the and we'll, before they start

50:49 let's start digging around and start figuring what's going on. So this is

50:53 what the field of anatomy is starting is in this, in this kind

50:58 prohibited environment. And scholars spoke in one of two languages, the two

51:04 dead languages that we don't use Latin and Greek, right? And

51:09 you are, you're an Italian and digging in graveyards and you're pulling out

51:12 bodies of people. And you're kind just trying to describe what you're doing

51:17 you have a colleague, somebody who's the exact same thing up in

51:21 And so what you want to do you want to have a common

51:24 right? To be able to describe . And the other thing you want

51:27 do is you want to make sure doing everything the same way, see

51:31 I'm dissecting my organisms with butt face down in a crouching position that's

51:36 going to do you any good. I'm describing what I'm seeing in a

51:41 to you, if you're dissecting a that's lying on the table, stomach

51:46 , right. So we need to some common language to help us understand

51:52 it is that we're looking at. so as we're going along, understand

51:56 the language that we're using was established that we have a common, a

52:02 language. All right. So if start calling things do hickeys, you're

52:07 gonna understand what it is. I'm about if you call the thingy,

52:11 ? Does that make sense? So the first thing that we did

52:16 you need to understand that there is common anatomical position. So you wanna

52:22 about it like this, even though always show a living person standing

52:26 going look at me, I'm standing this. No, that is a

52:28 person on a table. All That is the common position. Person

52:33 dead palms outward. That is the position, but we don't like to

52:38 about dead things. So it's a standing up arms out like so that

52:43 forward facing, this is not This is correct. So you always

52:47 to give yourself a high five or like that. All right, if

52:52 look at this body, we have main reg regions. The first main

52:56 is what is referred to as the region. All right. So it

53:00 from axis right. So where is axis? If you were trying to

53:07 an axis of something, what would be, would it be on the

53:10 or would it be central, central ? So the axial region is the

53:15 region. It consists of your head your torso. All right. And

53:19 net connecting them. All right. , there's an easy way to remember

53:23 . Your axis is consists of all parts you need to be alive.

53:27 right. So do you need to alive? I mean, would

53:30 do you need your arms to be ? Do you need your legs to

53:33 alive? It's helpful. But do need them? No. OK.

53:38 those are not part of the Do you need your torso to be

53:42 ? Yeah. Do you need your if I remove your head? Are

53:45 cool? No, maybe if you're worm but not as a human?

53:50 . So the axis is head through body centrally located. The appendixes are

53:57 things that hang off and dangle. fact, if you know what your

54:00 is, you now understand why it's an appendix. It's a dangly thing

54:03 hangs off your large intestine, your are appendices, your legs are

54:09 And so that's the appendicular regions of body. All right. So those

54:13 the two big regions. And then course, we can dive down deep

54:19 we can see that there are very regions in these areas. Now,

54:24 I throw up a picture like it is not your job to memorize

54:27 single pieces part that you see OK. I'm showing you this is

54:32 you can see now that we're using to help us focus in and identify

54:37 structures. And there's some of these you already know. So you may

54:42 heard for example of the planter region your foot, you may not have

54:47 planter as my foot, but you had planter wars, haven't you?

54:51 say no, no. I I know what you're talking about. You

54:54 , a planter's ward is right? a wart that's found on the bottom

54:57 the foot. It's not named after . It's named after where it was

55:01 a wart on the bottom of your . So that's planter's ward. All

55:05 , your armpits. That's the axial . OK. Here's an easy

55:09 Where's your pubic bone in the pubic ? OK. You know that

55:15 I know that many of you are . Look again, you guys are

55:19 going to health care, right? here taking the class just because you

55:22 nothing better to do and you just like fun. One person good on

55:26 . You guys get gold stars. right, cool. I hope you

55:29 fun. It's you too. I you have fun. All right,

55:32 this is gonna be fun stuff But part of the thing you got

55:35 get used to if you're planning on things is we're gonna talk about pooping

55:39 peeing and all sorts of dirty All right, these are the

55:42 the things that make you blush. is what this class is about.

55:46 planning on physical therapy. Couple of , you guys comfortable with your

55:51 you better be because first couple of after the first, the introductory

55:55 you get to touch one another, talking bicycle shorts and sports bras.

56:00 do I know this? My wife's physical therapist, she's not comfortable with

56:04 body, but she became very comfortable her body after the first week

56:07 hey, let's touch each other. right, you just have to,

56:12 ? You are going into a profession you are literally dealing with bodily function

56:17 if you're uncomfortable with naked pictures and like that, you're gonna have to

56:20 over it quick. All right. pubic area, right? Axiliary

56:28 OK. That's another one. Here's really fun one, the chin.

56:33 would I call the chin? It's mental region. Why? I don't

56:37 . It just is. Maybe because go, hm. Here's an

56:41 I don't know, I, I know. Here's an easy one.

56:45 this part called? And then it's sides temporal, right? So we're

56:51 learn if you don't know what temporal , we'll get to that because we're

56:54 see temporal multiple times. But it's are your temples, right? So

56:58 comes from temporal, temporal means Why do they call it the temporal

57:03 ? This one? I do know because when you start getting old like

57:08 , where do you first start So it starts showing time passing.

57:16 man, you're gonna find out most these things are, are pretty straightforward

57:21 you think about it. It's oh, that's why it's called

57:24 All right. So as we go , you're gonna start learning some of

57:29 and so just pick it up and like, OK, that's just a

57:31 term that I have to have to . All right, but I'm not

57:34 sit there and go. Here's a . What's this region? What's this

57:37 ? I'm not doing that. All . What I am doing is I

57:41 you to understand that you are made of a bunch of cavities and cavities

57:45 not the things that you find in teeth. All right, cavities are

57:51 spaces within the body. Did you the transition there from, from anatomy

57:56 this? See, this is what telling you look for those types of

58:00 ? All right. So cavity is hollow area in the body.

58:03 what we say is that a true is something that is fluid filled.

58:07 typically, when you're talking about this , there is fluid in that space

58:11 what you'll hear sometimes is a potential . Um Meaning that something that is

58:16 filled up but there is fluid in area. All right. Now,

58:20 cavities are named for the bones that them. And so we have two

58:25 cavities here. We have one that's the front and one that's in the

58:28 , the one that's in the back called the dorsal cavity. The one

58:30 in the front is called the ventral . So you should know dorsal and

58:34 as we go along. Easy way remember this, think about a fish

58:38 a shark or a dolphin. And that big thing in the middle of

58:41 back called a dorsal fin? So you ever get lost, just think

58:45 the dolphin, you'll remember that it's , oh yeah, he told me

58:47 think about dolphins and sharks dorsal All right. So that's the

58:52 All right. Now, the reason exist here is because you began life

58:55 a tube after you moved past a of those cell stages. And you

58:59 looking like an organism, you start as a tube and all vertebrates start

59:03 like that where you start off as tube structure. And so the dorsal

59:08 is filled with the structures that give to the neural system. And so

59:14 we have here is we have two cavities in this larger dorsal cavity.

59:19 one cavity is called the brain cavity the cranial cavity. All right.

59:24 so that is the part that is the brain. And then we have

59:28 spinal cavity. So you can see descending down here, that is what

59:33 housing the spinal cord. So that's too hard. And then the ventral

59:38 is this large structure that sits in front. This is what's going to

59:42 your viscera, your guts is what up all these other structures. All

59:48 . And if you look at this , you can see it's actually divided

59:51 two things really three if you get . But the top part is what

59:56 referred to as a thoracic cavity. we recognize the division of the thoracic

60:00 from the next cavity below it because is a membrane there that is a

60:06 and it's called the diaphragm. All . So above the diaphragm, we

60:10 the thoracic cavity. And then below , we have the abdominal pelvic cavity

60:16 we just combine those two terms, call it abdominal pelvic. All

60:21 Now, within the thoracic cavity, see that we can divide it up

60:27 more. And so we have two that sit on the side. These

60:31 called the plural cavities. They each contain a lung. All

60:37 And what we have surrounding each of lungs is a double sided membrane.

60:42 right, now, it's not really to see in the picture. In

60:45 , you can't see it in the . But you can imagine this structure

60:48 a membrane that has one side that's to the lung and the other side

60:52 next to the thoracic wall, the outside of the body. All

60:57 And so between that, those two , that's that space is filled with

61:03 and the membrane that makes up those walls, it's called cerus membrane.

61:07 the fluid inside is called cerus And so we call this plural

61:13 the pleura because it is covering the . That's the name. Now,

61:20 have special names for those membranes. remember we said double sided membrane,

61:24 part that's next to the lung is to as the visceral membrane. The

61:31 that is next to the thoracic wall called the parietal. Now, there's

61:37 easy way to remember this. All , your guts in your body are

61:41 to as the viscera collectively. All . So when we talk about your

61:46 , that's viscera, we talk about liver viscera. When we talk about

61:51 , your s you know, small , what is it viscera,

61:55 So the structures that make up these organ systems, they're collectively referred

62:01 as the viscera. So the part near the organ is the visceral,

62:05 part that's away from the organ is parietal. And that's going to be

62:09 . All the time. All So we have a plural cavity and

62:12 plural cavity. And as you can , we have the space in between

62:17 . So that space in between them referred to as the media sty.

62:22 right. So the space in between media, the middle part. So

62:26 just kind of this plural and then have this space in between and then

62:30 the media stum, that's where you're find the pericardial cavity, perry next

62:37 cardia heart, next to the heart . You see how the nomenclature

62:43 There's, it's really if you ever lost, take a step back and

62:46 , can I figure out what this actually means? I'm going to tell

62:49 this probably every other class. All , I'll go back and look at

62:53 word. All right. Now, , the pericardial cavity has the ses

62:58 , the Sears membrane, the part the heart would be called the,

63:02 her parietal. This and the part from the heart is the parietal.

63:07 as you see, it's gonna be no matter where you are. All

63:10 . Now, within the mediastinum, area that contains the pericardial cavity,

63:14 is where you'll find other structures. for example, your esophagus travels through

63:18 , the trachea travel through it, thymus is found in there. So

63:22 not an empty space. There are inside this cavity, but it doesn't

63:28 the Sears membrane that the pleural does the pericardium has when we get down

63:32 abdominal cavity. So the abdominal pelvic , we take those two halves.

63:37 the way I want you to just about this in really, really basic

63:40 is the abdominal cavity contains much, of the digestive system. All

63:46 And it extends upwards a little bit that there are parts of the rib

63:51 which are normally when you think about ribs, they're covering your chest,

63:55 they come down and they protect some the structures in the abdomen. All

64:00 . So it's partially protected. But you get down to the pelvis,

64:04 are no ribs. The pelvic cavity primarily the reproductive organs. Now,

64:10 I say that, understand that you know, human males, their

64:15 structure, their gonads are actually outside the pericardium or sorry, the the

64:20 cavity. But we just kind of for them that, yeah,

64:23 they're there. All right. So cavity, reproductive structures, abdominal cavity

64:32 structures. For the most part, things that are important in your body

64:37 usually covered by bone. Like think the thoracic cage. What's protected the

64:43 ? What's protected lungs? All digestive system, stomach protected. No

64:51 is protected. Kidneys are protected. right. And then when you get

64:56 to it, when you get down the pelvis, what's protected males?

65:00 . Ladies, uterus and ovaries are protected. All right. So they

65:07 structures in these cavities that are protected the bones that surround them.

65:18 continuing on, we're gonna look a bit at the nomenclature. All

65:22 So if you look at the abdominal cavity anatomist, again, we want

65:26 be specific as to what we're pointing and talking about. So we use

65:30 to make things as easy as And if you look at the abdominal

65:34 region, you'll see that what we is we have nine divisions which you

65:38 just do a tic tac toe and of put that up there. And

65:42 once you start looking at this, gonna see that we use terminology.

65:46 really want to sip here to help terms of our description. So we

65:52 descriptives. So you'll use things like and lower and left and right to

65:56 of if there's paired stuff to be to distinguish between those two things.

66:00 right. And so those are the of the descriptives that you kind of

66:03 here, right. So that would the left and the right and then

66:06 might be prefixes that can serve as . So this is where you're gonna

66:11 to start learning a little bit of these are. So hypo means

66:14 epi means above. And so when word is, begins with EPI just

66:18 it's above something. So there has be something that you're looking at.

66:22 epi, you know, and so this particular case, we have epi

66:28 . All right. So what is ? Well, gastric is coming from

66:33 actual structure, right? So gastric to your belly. So if this

66:40 your belly, right? I if you went to a little kid

66:43 said, where's your belly, what they do? They'd go right?

66:47 is not really a word we use anatomy, except in this kind of

66:51 . And it says if this is , what would be above the

66:54 Well, this region right here, above the belly, right? So

66:57 where the name comes from. And you start looking at these, these

67:00 making sense to you. So we hypo which means below chondritic.

67:05 what's a hypochondriac? That's someone who it, right? Yeah,

67:09 so that's not the word that we're for here. So, Chondra,

67:13 example, is the the the base for cartilage. All right.

67:20 again, this is the first day the anatomy. I don't expect you

67:22 know stuff like what my ribs are of up here. My ribs are

67:27 of bone, but they're connected by . And then when you get down

67:31 , what you have is you have lot of cartilage before you actually get

67:34 some real bone. So hypo right? That's what that's saying is

67:39 the cartilage or underneath the cartilage. this would be the left,

67:44 this is my right side, To you. It's my right because

67:48 gotta look at the body as it's , right? So this would be

67:53 well, I'm sorry, I got backwards, sorry, this is

67:56 So right, left, right, , left hypochondriac regions and then you

68:02 see some other ones here. Uh refers to the ilium, the bone

68:06 that lumbar refers to just this region the back. So that's the lower

68:11 region. So that would be what comes from where those terms come

68:14 And so you can all see, all of a sudden that when I'm

68:17 at my anatomy, I just need kind of understand what the words

68:22 I'm gonna promise you this, we're get into the nervous system and there's

68:26 be words that are like 10 and words, right? I mean,

68:30 gonna be like this long and you're look at them and you're gonna go

68:32 , uh, and I'm just telling right now, just stop and look

68:36 really in the nervous system, the they name stuff is where does it

68:40 and where does it end? So basically referring to one structure over here

68:44 another structure over there. And so two words are basically telling you this

68:47 the highway between those two points. guys lived here in Houston for most

68:52 your lives. Let me, let see the people who've lived here in

68:56 . All right, have you ever of Almeda Genoa Road? Yeah.

69:01 is Almeda Genoa? What two places they connect Almeda and Genoa? The

69:07 roads on either end of that All right. There are dozens of

69:13 like that in Houston. So you already see you already experienced this stuff

69:19 the time. You just need to that experience now to the anatomy

69:24 So, this is what an anatomist . Are you guys planning on being

69:27 ? Anyone here planning on being an ? There's like no one.

69:31 Yeah, that's what I thought. not an anatomist either. This is

69:35 you guys would be doing. So in the health professions, patient

69:40 into the, er, do you to sit there and go?

69:42 That is in one of the nine that's left, right? Ok.

69:45 . No, no, no. wanna be specific and quick and dive

69:49 in. So what they do is just do a simple crisscross,

69:52 lower left, right? And that's you get names there. They're

69:57 very quick. So you can see because there's four parts, upper and

70:02 left and right. Easy peasy. . So what you learn in your

70:08 classes, this is not the last class you'll take no matter which field

70:11 planning on going into, you're gonna it again because trust me, the

70:16 schools want you to teach you what want to teach you all right

70:21 this is common terminology. I'm not to go through all of these,

70:26 you should be familiar with most of , right. So, superior versus

70:30 , that's up versus down cranial coddle towards brain coddles towards the butt.

70:36 right, towards the rear. You see this term sometimes, but it's

70:41 more rare, rostral refers to towards nose. It's not in this

70:46 The ones that I think of that particularly hard are um uh distal versus

70:51 . All right, proximal means near distal means far away from. And

70:56 there's always gonna be a frame of . Typically, the frame of reference

70:59 to the the the core of the . All right. So if you

71:04 my arm, my elbow is proximal to, I mean to towards my

71:11 relative to my fingers which are distal away, right? So that's where

71:16 might see proximal and distal being Um Another one is um uh let's

71:22 here. Um No, it's not this list. Um Oh yeah,

71:29 it down at the bottom, deep superficial. Again, if you get

71:33 , superficial is near the surface, is further away or internal. If

71:38 wanna uh remember, this is really . Think about your friends,

71:42 Do you have friends who are Yeah. You know who I'm talking

71:47 . You pictured somebody when I said . Can you think of your deep

71:50 ? Yeah. People that you can in because you get down, down

71:55 dirty. Yeah. So superficial are the surface. Deep deed is

72:04 We have some body planes as All right. So again, there's

72:09 anatomical position that we described. You just like so and what this is

72:14 it says if I take your body slice it in half, I can

72:18 it in half in one of three ways. All right, I can

72:21 it down the middle, that's left right. I can slice you right

72:24 which up to uh versus uh top versus bottom and can slice you

72:30 this direction, front versus back. each of those have terminologies,

72:34 So if I'm slicing you front versus , now, it doesn't have to

72:39 specifically right in the middle of the , you can actually slice off the

72:42 of somebody's nose, right? And still front versus back. But if

72:48 do that, what I'm doing is am cutting you like, so do

72:52 see how from this angle? You see that? And what we're doing

72:56 we call that Coronal? All Now, when you hear Coronal don't

73:01 of the beer, although that's All right, Coronal ref is from

73:07 Latin, which means crown. when you think of a crown,

73:11 think of, you know the king or the tiara, the princess

73:16 right? Which goes like this. I want you to think about what

73:21 were, crowns are like what you on the Statue of Liberty, that

73:26 that radiates outward, it's supposed to rays of intelligence and power and

73:32 That's what it does. And so is basically that. All right.

73:36 it's dividing the front from the And what you're doing is, is

73:42 the crown as the radiation that All right, transverse, transverse is

73:48 you would do is if you cut in half in a magic half during

73:51 magic trick, right, that's top bottom. And again, if I

73:55 you here, that would be a cut, right. I'm separating your

73:59 from the rest of your body, ? If I cut you at the

74:02 , that's still transverse, all And then the next one is

74:07 which is left to right. So , what you'd see is like what

74:11 see in the picture here is if cut you directly in half and created

74:14 mirror image, that would be mid , that's a term that's often

74:19 but it is a sagittal section. could cut you here, right,

74:23 your arm from the rest of your that's still a sagittal. OK.

74:27 it's left to right. And that's easy way to remember. These is

74:30 to bottom, front to back, to right. And, and using

74:34 terms, there's another type of uh that we don't refer to because it's

74:38 and gross. But you may see someplace and that is called an oblique

74:44 . All right. Oblique means at strange angle that we're not defining.

74:48 right. So if I cut you this, that would be an oblique

74:54 . All right, if you work radiology and look at images, you

74:58 see oblique images and they're just harder deal with because top to bottom,

75:04 , to right front to back. easy stuff. All right, we're

75:09 down to the very ba uh to very bottom here we're releasing in about

75:13 minutes. I know you're like, ? Yeah, I'm the guy that

75:15 up all the time and I'm still for five minutes afterwards. All

75:19 So the last little bit here deals this question of homeostasis. All

75:24 So what is homeostasis simply is it's physiological principle that says a body's ability

75:31 maintain constancy or stability, despite the that the environment surrounding that body is

75:38 . And again, the environment refers both internal and external. All

75:42 So this is a dynamic state of . So that means it's constantly,

75:47 like standing in the middle of a totter or seesaw, right where you're

75:52 there trying to create balance, even one side is going up and one

75:55 is going down, you're constantly moving shifting to keep things balanced. That's

76:00 homeostasis is. All right. We that a body, body is home

76:05 homeostasis is homeostatic balance when all the are adequately met, right? And

76:12 is going well functioning smoothly. What guys are interested in, what you

76:17 chosen this field for is that you're in pathology. Pathology is when things

76:23 not going well, when things are up. And what you're trying to

76:27 is you're trying to achieve homeostasis, ? That's why you are probably in

76:34 class is because I wanna get people be in homeostatic balance. Now,

76:40 little image right here, these two are the exact same. You get

76:43 pick your, your, your OK. And what this is really

76:47 trying to show you is how homeostasis . All right. So what we

76:52 is we say the thing that we're at is the variable. So if

76:55 talking about temperature, temperature is the , if we're talking about uh blood

77:00 , that would be the variable, stimulus is simply the change,

77:04 So if you're looking up here at light and your eyes dilate, that's

77:08 more light is coming in. So stimulus is the brighter light.

77:13 So it's a change. And then we have to have in order to

77:17 change is you need to have some of sensor or receptor in the body

77:21 is able to recognize that specific So for example, your eyes detect

77:26 , is there anything else in your that detects light. So if I

77:30 a hole in your brain or in skull, and I put a

77:33 would your brain know that light is on it? No, because it

77:37 the receptors. The only place where receptors for light detection are located are

77:42 the eyes. All right. A is simply the thing that interprets what

77:48 receptor is, is experiencing, So the receptor takes the signal and

77:54 tells the controller, hey, I something changing and then the controller

78:00 hm, when change occurs in this direction, the response should be

78:04 And so what it's going to do it's going to cause change in your

78:08 . The easiest way to think about is with temperature. If it gets

78:12 , I have receptors that detect the , right? So that tells my

78:17 system, hey, you're getting So what do you need to do

78:20 order to reduce the higher temperature you to sweat? So then it sends

78:25 signal down to the effect or the that causes the effect. In this

78:31 case, it would be the sweat and it would say, hey,

78:34 glands start sweating and then that sweat absorb the heat and move the heat

78:40 from the body and your body cools . So what is, what are

78:43 doing? We're balancing ourselves around that range that we're most interested in.

78:48 that range is referred to as the point. All right. Now,

78:52 is showing you blood glucose levels, you could use this to show the

78:56 thing and just follow the thing what detecting the sensor is detecting and it's

79:01 for you to be within this particular . If I go out of

79:05 what happens? It tells the controller change, that effector talks to or

79:09 controller talks to the effector and it around and adjusts the response to bring

79:16 thing back into range. Last two really simple. How do we do

79:23 ? We'll use a mechanism. So is the mechanism that homeostasis uses.

79:27 is not homeostasis. We can use feedback. Negative feedback is the most

79:31 mechanism of regulation. If things I'm going to turn things on that

79:37 it go fall, it goes the direction. So the variable change in

79:42 feedback moves in a direction opposite of change, right? So again,

79:47 temperature, I get hot. What I want to do? I want

79:51 get colder, right? So that's in the opposite direction. That would

79:56 negative feedback. Most common type of feedback, the weird one that your

80:02 uses, that is far more It's not as common, it's used

80:06 very specific locations is positive feedback. is where the variable enhances the

80:13 All right. So this is the rolling down the hill. All

80:17 Yeah. Mhm No. So, let me get you. That's still

80:29 because if it's too low, then wanna move in the opposite direction.

80:33 right, positive feedback is moving in same direction. All right. So

80:38 gonna use an example that's not gonna everybody because you guys are probably most

80:42 you are too young to have experienced . But you've given birth, you

80:45 a baby and you are breastfeeding. right, baby begins to suckle milk

80:50 released through the nipple, right? sucking says, hey, make more

80:57 because the baby is feeding. So positive feedback is, you know,

81:02 I'm getting the stimulation right? So making milk and I'm gonna make more

81:07 and I'm gonna keep making milk until baby stops suckling. So in a

81:12 feedback loop, the thing that turns the system is outside the system.

81:17 does a baby stop feeding when it asleep and then you're no longer producing

81:24 . Yes, ma'am. No, not. I mean, I'm glad

81:31 are thinking about this. So like said, this is a rare

81:35 Typically we'll see these in like hormone , right? So we're trying to

81:40 things, make things bigger. so why vomiting is not? So

81:45 are you trying to do? You're to get rid of something out of

81:47 body. So what you're doing is doing the reverse of putting something

81:51 That's why. All right, when come back, we're going to continue

81:55 then we're going to jump into the . Yeah. Sorry about all the

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