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00:02 | How are you doing today? Let's . There we go. Um, |
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00:07 | got a report that the sound went in the latter part of the video |
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00:11 | . I don't know. So if does remember, I've recorded every video |
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00:15 | every class I've ever taught. So can always go back to previous |
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00:19 | Um, the jokes stay the I mean, it's really that |
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00:23 | So, um, I owe you a graph. Uh, I kept |
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00:29 | an, er, and I couldn't out what it was and I finally |
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00:31 | it was a person who looks like dropped the class, but they're still |
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00:34 | my roster. So it kind of shifting things and I just figured that |
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00:38 | about 30 minutes ago. So I'll that graph up online probably right after |
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00:42 | with an explanation of what grades are why you shouldn't panic. So, |
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00:47 | , that's something to look forward Ok. And then today we're going |
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00:51 | talk about bones. It's like that's today is his bones. Um, |
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00:58 | we're, we're first gonna start with of bone, what bone is, |
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01:03 | know how it's arranged. So we're look kind of deep into compact |
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01:07 | We'll look a little bit, more into uh, spongy bone. |
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01:10 | look at, see how bone is formed where it comes from. And |
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01:14 | what we're gonna do is we're gonna into, um, the actual bones |
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01:18 | the body. And yes, you learn all the bones of the body |
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01:21 | . It's, it's kind of scary you think about it because I think |
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01:24 | like 200 some odd bones. But good news, I mean, when |
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01:27 | hear that number, it's like what have to, yeah, 200 |
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01:31 | But like, think about your for example, there's 14 bones in |
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01:35 | fingers and they all have the same and you have two sets of |
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01:39 | So that's 28 bones just right So a lot of these are |
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01:43 | They have the same names like it's a rib, it's a |
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01:48 | So, you know, they're So we'll go through, you'll see |
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01:53 | pattern. It's not as scary or hard as it sounds. The hard |
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01:57 | in, in anatomy. And you're because I don't care, is learning |
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02:01 | names of all the muscles. So are, if you're going into physical |
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02:06 | and stuff, knowing all the muscles important, becoming a nurse, I |
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02:10 | know, it doesn't seem to be important, you know. So we'll |
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02:14 | kind of understand the nomenclature when we the muscles, but we won't have |
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02:17 | name all 600 muscles in your And I do have colleagues around the |
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02:26 | that teach all the muscles. I bad for their students. All |
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02:33 | So what I want to start here is I wanna look at some of |
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02:36 | features or characteristics that each bone All right. So there's markings. |
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02:40 | when you pick up a bone and at a bone, what you're gonna |
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02:43 | , especially if you're doing the they're gonna sit there and say, |
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02:45 | your landmarks, learn the different characteristics each of these bones that you can |
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02:50 | them. All right. And that's not the important part here. |
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02:54 | question is why are these landmarks actually ? What, what, what purpose |
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02:58 | they serve? And so we have types, we have depressions, openings |
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03:02 | projections, that's kind of the big . And then each of these have |
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03:06 | names. And so you'll come across like fossa, you'll come to learn |
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03:10 | just remember, you know, we're to see fossor in just a |
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03:14 | But what these are, these depressions where are allow one of something to |
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03:19 | , right? So first, you have a, a place where a |
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03:22 | meets another bone. All right. so this is a way that these |
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03:26 | bones can interact. So they're not and sliding over each other in inappropriate |
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03:32 | . All right. So that would one example of a depression, but |
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03:36 | type of depression might be where a vessel or a nerve travels. And |
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03:40 | like on the rib, for you're gonna see, um again, |
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03:44 | probably in this class, but more the lab, you'll see this depression |
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03:48 | this facet uh is where the nerve the blood vessel travel alongside the |
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03:55 | right? And so that's why it's . So it creates a divot for |
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03:58 | things to happen. And then the thing is this articulation. So at |
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04:03 | joint where you can get these two to slide against each other in |
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04:06 | in a, in a, in manner that allows them to actually create |
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04:10 | sort of force. That's another place you're gonna see a depression. So |
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04:14 | now, the names aren't so right? If you were at community |
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04:20 | , what do you think they'd make , do you think they'd make you |
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04:22 | these? Yeah, they would. . I want you to start learning |
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04:27 | as you come across them and understand they mean. Ok. Because I'm |
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04:32 | just point to things I'm gonna say is an eon and then you're gonna |
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04:35 | , OK. Well, I remember eon is a projection. What is |
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04:38 | purpose of that projection, that sort thing? Ok. That's kind of |
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04:41 | we're going. So these are kind depressions, kind of a stupid |
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04:48 | We have a couple of different types openings, openings are called holes, |
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04:52 | know. Right. They're basically things things pass through. What type of |
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04:55 | are gonna be passing through, primarily vessels and nerves. All right. |
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04:59 | we're gonna see some major ones. the, the key one that you're |
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05:02 | see here is a, the other is gonna be a and if there |
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05:06 | many of them are called for all right. So the big hole |
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05:11 | your, uh in your skull, we're gonna see here in a couple |
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05:14 | minutes is called the Forman Magnus. do you think for? And Magnus |
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05:19 | framing is whole. So what do think Magnus big? It's the big |
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05:26 | . That's, that's what they called . So just because they use Latin |
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05:31 | make it sound fancy, doesn't mean it's something fancy. It's really a |
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05:35 | . All right, fissures are another . So here you can see in |
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05:38 | frontal bone, here is the super frame and you'll notice that the name |
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05:42 | you everything about it sura above that's that cavity. And then, |
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05:50 | it's above the, the eye cavity whole. Excuse me. That's just |
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05:55 | example. All right. And then all sorts of different types of uh |
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05:59 | . So again, here's a whole of different types of projections. They |
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06:02 | fun names like tubercle, tubercle is a fun word to say. So |
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06:06 | try it, tubercle, anything with at the end sounds fun, |
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06:10 | Tuber coal. But you got crass epics, you have processing spines per |
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06:16 | . Do these words sound like things poke out, that stick up and |
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06:20 | do and, and in essence, are places where muscles are going to |
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06:23 | attached, where tendons are gonna attach ligaments and they have all different types |
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06:28 | shapes and those shapes. Um, words that you see are descriptive of |
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06:32 | shape. So when you look at scapula, for example, we're going |
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06:35 | see the spine. And when you of spine, what do you think |
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06:39 | something you elongate that sticks up, ? Like like a bunch of |
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06:44 | create a spine, the spine of world type type of stuff. And |
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06:50 | really, when you're looking at the , it should kind of uh jog |
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06:54 | in you that says, oh this is a descriptive word to help |
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06:57 | better understand what this thing sticking up like. All right. So when |
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07:04 | see these things, understand that they're to help you understand the purpose of |
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07:09 | bone, not so much, just , oh, now I know what |
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07:11 | bone this is because trust me, gonna be able to tell the difference |
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07:15 | most of these bones. You when you go in the lab, |
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07:18 | pick up a humorous and you'll be to tell the difference between a humorous |
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07:21 | a femur that, that's pretty you know, one's like this one's |
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07:25 | this. All right. Now, the bone. We have marrow and |
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07:33 | two different types of marrow. We red marrow and yellow marrow, red |
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07:38 | in this picture right here, it's . You have to look better is |
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07:42 | on the side. You can see red on the outside. Then there's |
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07:45 | yellow area on the inside. This on the outside is the red |
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07:49 | This is what we refer to as hemopoietic or hematopoietic. Either of those |
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07:53 | terms are co correct. I learned as amato poetic, but they got |
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07:57 | of the ato in the middle and just call it hemopoietic. All |
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08:00 | Now, this type of tissue, you see the word hematopoietic, this |
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08:04 | a tissue that produces blood cells, ? That's what that term means. |
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08:10 | poetic or hemopoietic. So we're it doesn't matter if we're talking erythrocytes |
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08:14 | white blood cells. But just you're producing red blood cells far more |
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08:19 | you're producing white blood cells. So why it has this reddish appearance right |
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08:24 | where this stuff is located, depends what age you are. When we |
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08:28 | looking for it in adults, the red marrow is very limited to where |
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08:34 | actually located. It's very difficult to or I shouldn't say difficult to |
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08:38 | It is difficult to reach. That's a better term. All right, |
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08:42 | find it in the ends of the bone. So where the spongy bone |
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08:45 | in the long bones and the, um, epithets. That's where you'll |
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08:50 | red bone marrow. You'll find it in the of your flat bones. |
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08:56 | your flat bones would be like your , your hip bones. And so |
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09:00 | can imagine if you're a bone marrow , you have to go into some |
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09:05 | horrible places to get that stuff. . Because it's, it's not easy |
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09:10 | get to those places. All But kids, Children have red bone |
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09:15 | everywhere because they're in this constant state growth and they're constantly producing red blood |
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09:21 | as they're growing. So you could cut in any sort of bone and |
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09:24 | even find it in the med So those elongate cavities in the diathesis |
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09:29 | filled with red marrow as a as child. So there it's easy to |
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09:34 | to. Now when you age, happens is is that this marrow here |
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09:40 | the medullary cavity gets replaced by that marrow in adults. So this is |
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09:47 | I say the older you get, more fat you get right? Because |
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09:51 | actually there inside the bones as you're . Now, what this is is |
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09:57 | adipocyte. So it is truly a . But if your body gets in |
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10:02 | state where it's in desperate need for blood cells, what will happen is |
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10:07 | red blood cells in the red marrow begin amping up and those stem cells |
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10:12 | will start moving around into the yellow and start replacing that yellow marrow with |
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10:18 | red marrow again. All right. it's not like you, you lose |
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10:23 | yellow or that red marrow. It's that you don't need to produce as |
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10:26 | red blood cells as kids do. so that's kind of the difference. |
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10:30 | as you get bigger, you primarily with yellow, with the exception of |
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10:36 | places, I describe the hard, hard to reach places, but then |
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10:40 | can revert if you need to. whenever we talk about a tissue, |
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10:47 | we're really today is kind of tissue and organ day because you don't think |
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10:51 | bones as being an organ, but are an organ and bones if it's |
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10:55 | organ are derived from tissues and the of tissues we're dealing with here is |
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10:59 | tissue. All right, that's just fancy word for saying bone, the |
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11:03 | as opposed to bone, the right? That ose tissue, remember |
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11:08 | are made up of groups of similar . And so in this case, |
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11:13 | dealing with the connective tissue that's primarily , but that means there's still cells |
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11:17 | that are responsible for those cells. so what I wanna do is I |
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11:20 | to first focus on those cells, we'll talk about the tissue and then |
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11:24 | when we'll jump on to the organs memorize all our 200 some odd |
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11:30 | OK. So there are four major types that are found in osseous tissue |
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11:35 | they're enlisted here, Osteoclast, which not related to the other three. |
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11:39 | then the other three are related. start with the osteogenic cell which can |
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11:43 | the osteoblast which then will mature and the osteocyte. All right. So |
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11:49 | we see blast at the end of world, what does it mean? |
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11:51 | you guys remember immature? And then we have sight, it means |
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11:55 | right? And whenever you see osteo when you ever see genic or |
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12:00 | it's, it's referring to the stem of that line. It's not a |
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12:05 | cell that can become anything, it's for this particular line. All |
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12:09 | So we want to start with the cells. All right. So the |
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12:12 | one, the one that's kind of as a stem cell is that |
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12:16 | it's mitotic, it sits around and basically replicates and keeps a population of |
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12:22 | cells around. But it gives rise those osteoblasts right now where we find |
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12:28 | . If you recall, we said have that compact bone and we have |
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12:32 | spongy bone inside and surrounding the compact on the outside is that periosteum and |
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12:38 | basically connective tissue, but right next the bone, that's where we're gonna |
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12:43 | this living layer of cells. So gonna find those osteopro cells there in |
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12:48 | periosteum and then inside the, the itself where the lattice of the spongy |
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12:53 | is, you're gonna find them there well in that endosteum. All |
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12:59 | So this is where they're gonna be . But because their job is to |
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13:03 | osteoblasts, you'd expect to find osteoblasts as well. Right. And you |
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13:08 | . So there's osteoblasts as well found the periosteum and the endosteum. So |
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13:14 | can see here where we are here the cells that have differentiated. |
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13:18 | here's the osteogenic cell, what they're is some of these are staying behind |
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13:23 | what they're doing is they're producing these cells that are going to become |
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13:27 | So now they're being labeled here as . Osteoblasts are immature cells. Their |
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13:32 | is to produce matrix. And so what they do is they start laying |
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13:37 | matrix, they lay down matrix below . And then what happens is, |
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13:41 | as they start releasing this matrix, actually they start pushing up and some |
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13:46 | them get trapped inside their own right? So the bone is being |
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13:53 | because of those osteoblasts. And then happens? They get trapped inside their |
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13:58 | matrix and then now they differentiate and , OK, I'm no longer going |
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14:03 | make matrix. I'm going to maintain matrix, make sure the matrix is |
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14:08 | . So it's doing the job that was built to do. So that's |
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14:12 | the osteocyte does. It can't make new bone, they just hang out |
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14:17 | the bone matrix that they created, very much alive. They have uh |
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14:23 | kind of these um extensions from their that go out and touch other osteo |
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14:30 | or sorry osteocyte. So they actually to each other and they detect the |
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14:36 | inside the bone to make sure that bone is resilient enough to do its |
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14:42 | . So for example, when you , every time you take a |
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14:45 | that bone has to bear the entire of your body. And that tension |
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14:50 | felt in the bone and the osteo sites can detect whether or not it's |
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14:56 | appropriately to that degree of stress. kind of cool. And so they |
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15:02 | to rearrange the matrix, make sure it's uh being maintained. So those |
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15:09 | the three osteogenic cells, osteoblast makes osteocyte maintains it. Osteopro geor is |
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15:14 | stem cell pretty straightforward, right? far, so good. Then we |
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15:20 | the osteoclast. Now, these are unrelated, but they still work on |
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15:25 | bone. If the osteoblast is responsible , for building bone, the osteoclast |
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15:31 | responsible for breaking down bone. All . So, wait a second, |
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15:36 | would I wanna break down my Well, if your bone has been |
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15:41 | down inappropriately, I want to break apart. So it's no longer doing |
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15:46 | inappropriate work. And what I wanna is I want to rebuild it so |
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15:50 | it does the work that it All right. Now, they come |
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15:53 | a different line of uh progenitors and they do. I love kind of |
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15:56 | picture, it kind of like looks this, this line that sits there |
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16:01 | you know, it grinds everything But in essence, it's kind of |
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16:04 | it is. It basically breaks the down and weakens bone in different areas |
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16:08 | it releases that calcium phosphate which makes the matrix so that the osteoblast can |
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16:13 | that stuff up and redesign and rebuild bone so that it works. All |
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16:18 | . So this process is called All right. So the matrix is |
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16:24 | built by osteoblasts, but the osteoclasts resorb the bone. And this is |
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16:33 | best picture I could find that kind shows it goes through the process. |
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16:36 | can pick any point where you wanna . All right, we're gonna start |
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16:40 | here in this top corner. All . And what this shows is the |
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16:44 | of absorption of bone. And so know this is kind of look like |
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16:48 | Inky Blinky and Clyde, you know those are? Right? Oh My |
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16:55 | , you guys are young. Those the three of the four ghosts in |
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17:03 | . Do you see them now? BK Blinky and Clyde. I think |
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17:08 | pinkies in there also, but Clyde the fun one. All right. |
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17:12 | here you come along. So here can see that the matrix is, |
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17:16 | has some sort of weakness in All right. Now, obviously, |
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17:20 | our case, the weakness was formed the osteoclast here. But let's just |
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17:23 | we're here on a uh a spongy , we can see that the matrix |
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17:27 | doing its job, it's not properly . So the osteoblasts migrate into the |
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17:32 | . And what they do is they down osteoid, that osteoid there reinforces |
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17:38 | bone and allows it to deal with stress that this lattice right here is |
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17:44 | for addressing, right. And once lay it down off, they go |
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17:48 | they travel off to wherever they need , to find the next bone that |
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17:51 | to be done. Uh But your no longer needs this one. You're |
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17:55 | applying that stress anymore, or your needs to release calcium for other |
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18:00 | So this is when an osteoclast comes , breaks down the bone where |
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18:05 | it's OK to break it down and release those calcium phosphates and stuff, |
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18:10 | calcium and the phosphate and the uh material. And now that stuff can |
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18:15 | used by the body for other And it's like, oh no, |
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18:18 | we have stress again. So we keep rebuilding bone. Now, this |
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18:24 | kind of a, a simple model . But I want, I want |
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18:28 | point out just take your daily What you've been going through about 5 |
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18:34 | 7% of your bone mass is recycled week. All right. So if |
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18:39 | want to put that in perspective, get that up to 100% that would |
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18:42 | 20 weeks, right. So every weeks, your body remodels the equivalent |
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18:48 | your entire skeleton. That means twice year, you rebuild your skeleton almost |
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18:55 | times a year. Isn't that So, this is not, not |
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19:00 | tissue. This is very much a tissue. It is very active |
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19:04 | If you think about what you're doing . Right? And so what we're |
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19:10 | when we break it down is we're calcium available and you're gonna find out |
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19:15 | is one of these uh these uh that is ridiculously important in your body |
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19:22 | . We don't pay it much right? It's how your muscles |
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19:26 | It's, I mean, smooth it's as well as your skeletal |
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19:30 | It's how cells communicate with each It's responsible for all sorts of |
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19:34 | And one of the purposes here of bone is to store up calcium for |
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19:39 | you need it. It makes your strong, but it's also about a |
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19:44 | other jobs. So you guys kind get the picture here. What's going |
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19:49 | ? Osteoblast, break things down, , make or build things up. |
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19:54 | , break things down and it's not . It's based upon need of the |
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19:59 | . So if the bone has need building up uh strength, then what |
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20:04 | gonna do, it's gonna build along stress lines. If it sees something |
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20:08 | no longer is needed or is unused it doesn't meet the needs of the |
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20:12 | , it will break that down and where the remodeling takes place so |
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20:18 | So good. Yeah. Yeah. strong. Mhm. It's gonna |
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20:27 | it's gonna be breaking down and it's gonna be like, don't think of |
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20:30 | as I'm breaking down the bone, breaking down little itsy bitsy portions of |
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20:34 | bone that are no longer used. gonna learn here in just a |
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20:37 | Something called wolf's law. All I'm just gonna say it now because |
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20:40 | law is easy. It's one of , one of the easy physiological laws |
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20:44 | you can memorize. Wolf's law basically your bones are gonna be as strong |
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20:48 | you need them to be. That's it says, right? So your |
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20:53 | as you use them will become stronger upon your need. It's kind of |
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20:58 | my muscles will be as strong as need them to be in order to |
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21:01 | the function. So what do I ? I go and work out? |
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21:05 | my muscles will grow until they no need to grow any further. |
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21:10 | there's a limit to how big muscles get. There's also the truth. |
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21:15 | also, there's a, there's a to how big your bones can |
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21:18 | But let's paint this scenario if all do is sit on the sofa all |
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21:22 | long and you never get up and to go to the bathroom to the |
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21:26 | , do you need strong bones? . All right. No. So |
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21:31 | body doesn't waste the time and the building bone to do some sort of |
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21:35 | activity that you're never going to Instead if you run and exercise, |
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21:41 | mean, you don't even have to . If you get up and walk |
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21:43 | and do things and lift things and things, move your body, then |
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21:49 | putting stresses on the bone and the responds by building the bone stronger. |
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21:56 | . That's the idea of wolf's It builds the bones to fight the |
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22:01 | that it normally has to deal with that makes sense. So every time |
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22:05 | take a step, you're putting that weight of your body on that bone |
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22:09 | that bone receives the stress and so structures and strengthens the bone so that |
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22:14 | can respond to that if that makes . Yeah. OK. It's not |
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22:20 | to say, hey, how many are you gonna lift the two ton |
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22:24 | ? You know, that's, that's of the realm of what the bones |
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22:29 | . All right. So what is bone? What, what is it |
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22:32 | up of? Right. Well, , there's different aspects to the |
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22:37 | all right. And so what we're in this little picture here is we're |
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22:41 | at the mo molecule level and then kind of working up to the fiber |
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22:46 | and then from the fiber level, actually building structure within our actual |
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22:51 | So just to kind of give you sense of this would be the outside |
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22:54 | the bone. This would be the cavity of a long bone. All |
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22:58 | . So we're looking at a slice a pie taken from a bone is |
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23:02 | of what you're looking at, And this is a long bone where |
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23:05 | I took a cross section through it I was looking at it this |
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23:08 | you're kind of looking at that top . All right. So you can |
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23:13 | here here's compact bone, compact compact bone comes up to here and |
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23:16 | you have this lattice work that spongy and then everything over here would be |
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23:21 | cavity. So you kind of kind envision that. All right. So |
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23:27 | you're looking at bone, it has an organic component and an inorganic |
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23:34 | right? Organic, what does that ? Well, these are the |
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23:39 | these are things the biomolecules. And we're talking about collagen, which is |
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23:43 | protein. And you can see over this is what collagen looks like. |
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23:47 | then you take those strands and you them with other strands. So you |
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23:49 | these really, really tough uh troo . He he so you can see |
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23:54 | is a rope like structure and then take all these things and you bundle |
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23:57 | together. So you get this big bundle and so these are the fibers |
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24:02 | make up a bone. And then we're gonna do is there are gonna |
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24:07 | cells that are gonna be uh responsible this or around this. And so |
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24:11 | gonna deal with the cells in just moment, but ultimately, this |
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24:17 | this collagen in this arrangement is what the bone its strength. You can't |
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24:25 | it, you can't stretch it. It's, it's just really, really |
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24:30 | and really, really rigid because of arrangement of fibers. Now by itself |
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24:37 | that's resistant to stretching and twisting, still not hard. This is where |
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24:44 | inorganic comes in. So we're gonna in these crystals, these salts, |
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24:49 | called a uh appetite crystals. A T I T E aetate appetite, |
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24:55 | it's calcium phosphate is what it So it's salt and so basically what |
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25:00 | doing is you're preserving these fibers in uh uh uh salts and that makes |
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25:07 | matrix rigid. So, whereas collagen , I mean, like like in |
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25:15 | is mobile, I'm just gonna play my nose for a little bit, |
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25:19 | ? That's cartilage. It moves around fine. But if I get up |
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25:22 | to the top where it's bone, doesn't move. That's just my skin |
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25:26 | on top of the bone. When break your nose, what you're doing |
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25:30 | you're just breaking that bone up right? You're not breaking the |
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25:35 | Cartilage is bendy, right? What doing is you're ripping and tearing those |
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25:44 | that I've hardened in their nature, ? So this is what gives it |
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25:50 | and inflexibility. Um, they just them. All right. So I |
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26:01 | talk about, uh Taylor Lawrence uh Joe Theismann here. But I |
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26:05 | I've probably outage you guys at this . So you probably don't know who |
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26:10 | of those two people are. Yeah. So we won't talk about |
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26:15 | . All right. So here we again. And we're looking right. |
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26:20 | here's your compact bone, compact bone then here in the middle, there's |
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26:24 | matrix. So we're doing that slice a bone again. And you can |
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26:28 | we got these really weird ring looking . These are called osteon. The |
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26:36 | is the structural unit of a compact . So again, I want you |
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26:40 | think in perspective, we're looking at long bone and we've made a slice |
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26:45 | the diathesis and you can see through slice that you have a series of |
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26:50 | that are repeated over and over and again. And if you look at |
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26:54 | , they kind of look like a eye, right? So there's like |
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26:56 | outer rings and middle ring and inner . And then there's this like hollow |
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26:59 | point in the middle, you kind see this here. So there's the |
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27:04 | kind of represent the boundaries between the in this picture right up there. |
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27:10 | right, if you look here, can see the dots and they're trying |
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27:13 | show you there's the ring, there's ring, so on so forth so |
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27:16 | can, you can, you can what we're talking about. We're talking |
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27:19 | the osteon. All right. when we say this is a structural |
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27:24 | , what we've done here is we've these osteoblasts and they've been growing the |
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27:30 | , they're laying down matrix that creates different rings. And these little dots |
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27:38 | where those osteoblasts got trapped. And that's where they exist now. So |
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27:43 | are osteocyte inside those little tiny black . OK. So your bone has |
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27:51 | cells inside them stuck in these Now, you can see when we |
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27:57 | one of these things out what it like. We have uh an inner |
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28:02 | , a middle ring, another ring then there's another ring around it and |
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28:04 | just these series of, of And if you look, the fibers |
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28:09 | being represented by these lines and the go one direction and then they go |
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28:14 | other direction and the next one, go the other direction. And what |
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28:16 | done here is you've created a pillar has a series of fibers that are |
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28:22 | themselves as they move further and further . So if one fiber is going |
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28:26 | way and one is going that basically, they're, they're moving in |
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28:29 | direction. So the torsion or torque you would apply to it is going |
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28:33 | be resisted because of the different directions the fibers, right? When you're |
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28:39 | kid and you're doing paper mache you , you put one fiber down this |
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28:43 | and then you put another one like . All right, I'm probably missing |
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28:49 | spot on that one because you probably remember playing with paper mache. You |
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28:54 | that plywood is particularly tough. Have played with plywood? Right? P |
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28:59 | is basically wood fibers which were all in the same direction and then you |
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29:03 | it all up and you throw it and you give it some glue. |
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29:06 | now the fibers are going different If you can get more strength out |
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29:09 | a thinner board of plywood than you with a normal cut piece of wood |
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29:15 | the fibers are going in opposite they reinforce themselves in very different |
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29:22 | And so these pillars which are hundreds and hundreds and hundreds of times |
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29:29 | the compact bone are there to give resistance and the strength to the |
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29:36 | So it's not just that the presence the fiber is there, it's their |
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29:39 | as well. So if we take closer look at an osteon, so |
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29:49 | , here we are right, here's osteon, we've pulled it out. |
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29:53 | looking at, we can see the going in opposite directions. And what |
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29:56 | gonna do is we're now just kind focusing in with all the different rings |
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30:01 | of smashed together. Now, we see there is a unique arrangement in |
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30:06 | . And again, I know this cartoon, here's an electron micrograph. |
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30:09 | a microscopic view of the same All right. And what you can |
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30:13 | is that in the middle of every , there's this big giant gaping hole |
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30:17 | contains a nerve fiber, an artery a vein. So where you have |
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30:23 | and veins traveling, that means you're moving blood between two points. All |
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30:29 | . So this central area is called central canal. See how clever that |
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30:34 | . So there's lots and lots of canals. The central canal is not |
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30:38 | medullary cavity that's way over here, ? It's within this little tiny |
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30:43 | So there's a central canal. All . And then each of these rings |
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30:49 | referred to as concentric Lamela, So Lamela is the name of the |
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30:55 | because it's round in nature, it's to as being concentric. OK. |
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31:01 | where the name comes from. And you have multiple concentric rings, multiple |
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31:06 | Elli. All right. And that's the fibers are going in opposite directions |
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31:12 | the boundaries of the la. So can see right there, they look |
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31:16 | these weird, strange looking eye maybe little alien looking things. Those |
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31:21 | the osteocyte, those were the cells got trapped and are now responsible for |
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31:26 | out the matrix and determining whether or they're, it's doing its job as |
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31:31 | terms of resisting stress and torsion. right, they live inside a little |
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31:36 | space called a lacuna. Apart from Mata what does lacuna sound like? |
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31:47 | word comes to mind when you hear . What's that lagoon? That's exactly |
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31:54 | word I'm looking for. They exist a pool of fluid that surrounds |
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32:01 | It's like a little mini lake and fluid has a lot of calcium |
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32:05 | it has a lot of phosphate in . And what they do is they |
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32:09 | , they can add and subtract the to and from their immediate surrounding |
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32:15 | And this kind of serves as a to be able to say, oh |
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32:18 | , what we need a little bit calcium. Ok? Well, instead |
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32:21 | waiting for you to go consume milk spinach, um I will loan you |
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32:24 | little bit of calcium. So it you to manage calcium um production and |
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32:32 | in this little entirely environment. But can just think of it. The |
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32:36 | or the lacuna is where the osteocyte between the lay the rings that they |
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32:44 | down when they are osteoblasts. And finally, we have these little |
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32:50 | extensions of the osteoblast and they move each aid osteoblast osteocyte. And this |
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32:58 | the osteocyte to talk to each but there's a little tiny canal through |
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33:03 | that little extension goes and we call little tiny canals Nili. All |
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33:10 | So the exists between these and it's easy to see. I'm obviously one |
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33:15 | these pictures right here, but you see how they kind of extend |
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33:19 | Right. And here you can see these are little tiny lakes, little |
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33:23 | lagoons and that's how I remember. right, so far, are you |
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33:29 | me, with the structure? what's a lacuna, the place where |
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33:33 | osteocyte lives? What's the place where extensions are? What's a, it's |
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33:40 | ring? All right. Now, central canal goes up and down. |
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33:46 | right. In order to get the vessels in the nerves, there, |
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33:49 | has to be something that penetrates through bone so that it then goes up |
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33:53 | down through the osteon. All And so we have a name for |
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33:57 | and you can see them right They go in and then you're going |
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33:59 | and down here we go. Those called perforating canals, right? So |
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34:04 | got a central canal, the way get to the central canals, you |
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34:06 | to the perforating canal. All So they're right angles. So central |
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34:11 | go up. So there's tons and of central canals and there's perforating canals |
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34:15 | allow that to happen. And then the outside of the bone. Remember |
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34:20 | here, you can see here. that structure right here called this thing |
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34:24 | we're tearing away periosteum? Good. heard it. So, periosteum, |
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34:29 | on this side? End? All right. And we said there |
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34:33 | layer living cells underneath the connective tissue the periosteum, right nearest the |
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34:40 | And those cells remember are osteopro and osteoblasts and osteoblasts, their job is |
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34:45 | lay bone, right? They're putting bone. And so what happens is |
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34:50 | they're putting down bone, they're creating own giant LALI and they are found |
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34:56 | the outside edge of the bone. when you think about a circle and |
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35:03 | distance around a circle, what do call that circumference? So it is |
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35:08 | the circumferential la. And you'll see we have circumferential Elli on the inside |
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|
35:16 | well. All right. OK. , how do we distinguish them? |
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35:20 | , one is external, one is . So we have the external |
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35:26 | see going all the way around, the way around. And then over |
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35:32 | we have this network of LALI going the way around. That would be |
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35:36 | internal circumferential lamel. All right. that's how we define the boundaries of |
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35:45 | compact bone and it's being laid by osteoblasts that are found in the |
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35:53 | And on the end stum now, you had a bunch of straws in |
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36:00 | hand, straws are perfectly round, I could say dolls, but you |
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36:04 | , I don't know what a doll , right? But if you had |
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36:07 | , I'll just pull up one of pins. So if I grab his |
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36:11 | and put them together and they didn't these little things. Would there be |
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36:15 | bitty spaces in between each of these structures? Yeah. So your bones |
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36:20 | have a lot of hollow space, is not a good idea. |
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36:23 | Because if you had hollow space in bones, what would happen? |
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36:26 | they would, they would, they lack the strength. So, in |
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36:33 | all these round is the space that to be filled up. And so |
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36:39 | as your bones are being developed are those spaces and they fill them up |
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36:44 | bone. And we refer to this the interstitial. So whenever you see |
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36:51 | word interstitial or inter, it means stuff inside or between. So |
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36:59 | el these are the lay of the and then the stuff in between are |
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37:06 | interstitial Elli. All right. And these are either laid down or what |
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37:14 | happen is, is like, well, this osteon isn't doing its |
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37:17 | . So, what I'm gonna do I'm gonna break it all down and |
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37:20 | gonna rebuild an osteon. And so this might be remnants of an old |
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37:25 | that was destroyed. And where as new osteon came up in around |
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37:30 | that kind of makes sense. So compact bone is compact because all the |
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37:36 | is filled with bone material with All right, or osteoid is the |
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37:42 | term here. So, do we structurally what's there? So, what's |
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37:48 | osteon? What's in the center let's start this, what's in the |
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37:52 | of an, you can look at picture, I'm not central canal, |
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37:59 | ? And then what are these? are a series of starts an L |
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38:06 | . All right. What's at the of all the Lomeli, one of |
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38:12 | little black dots osteocyte. And what they live in? Lacuna? And |
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38:18 | they talk to each other via And then how do I get those |
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38:24 | blood cells or not blood cells, uh blood vessels in the nerve up |
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38:28 | the uh central canal, perforating And then the thing that makes up |
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38:35 | boundary of the bone is called the . One on the outside is |
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38:41 | the one on the inside. Good. See, and then the |
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38:44 | in between is interstitial. If you the information in a way that makes |
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38:51 | to you, this is what makes to me, makes sense to you |
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38:54 | it out easy. Peasy. Spongy bone is arranged like a |
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39:03 | It doesn't have these osteon instead of of this open lattice work. What |
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39:08 | refer to this lattice work as our . If you ever watched Jeopardy, |
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39:15 | have Alex Trebek tribe, I don't , help, right? But |
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|
39:21 | it's just these, these, these of bone that kind of look like |
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39:25 | osteon. You can see they have series of there's just no central |
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|
39:30 | right? You just have la there's osteocyte stuck in lacuna. These |
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39:34 | lacuna have that go to the to outer la and so they can get |
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39:40 | nutrients from the surrounding environment. So don't have to have blood uh uh |
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39:46 | through osteon to them. And so can imagine if this is a, |
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39:49 | is a cutaway through one of those and these are built along stress |
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39:57 | So this is where the primary work breaking down bone is actually taking |
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40:02 | It can take place in compact but you don't do so quite as |
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40:08 | . But this is where you would it because a bone needs to be |
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40:12 | and modified as you use it. right. So we refer to these |
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40:18 | parallel cause reasons, no blood And then you can see if you |
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40:27 | at the picture probably over there, can see there's a little tiny dots |
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40:30 | are representing the conic open to the . All right, same sorts of |
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40:39 | , different names, different structure. . And these are again built along |
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40:46 | lines. So while it looks remember what I have is I have |
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40:50 | that are detecting the degree of stress that bone structure. And so it's |
|
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40:54 | no, no, we gotta build this direction. So that's what the |
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41:04 | is. All right, how we these tissues is through a process called |
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41:10 | or osteogenesis. All right. And , most of these words, you |
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|
41:16 | probably figure out if you had just little bit of time to think about |
|
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41:20 | . All right. Now, this very early on during embryogenesis, |
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41:26 | So as you're developing, you, start off uh building bone very early |
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41:33 | and it's gonna use one of two , what is called intramembranous ossification or |
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41:40 | ossification. All right. Now, switching the slide was intramembranous mean, |
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41:50 | by itself intra inside and then inside membrane. OK. And what do |
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41:55 | think endo inside and then control All right. So here, what |
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42:04 | gonna see is that we're gonna just just start developing bone within a structure |
|
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42:11 | it's just gonna naturally start forming. right. But here we're gonna have |
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42:17 | cartilage first and we're gonna replace the with the bone. That's all those |
|
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42:22 | things mean. All right. So begins very early on. It continues |
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42:29 | through childhood and it will continue on adulthood right now. You are going |
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42:34 | endochondral bone development and you don't even it. All right. And it's |
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42:40 | because you guys are young. It's , it will keep happening until you're |
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|
42:43 | 40 years old. All right, gonna see. We have a, |
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42:47 | bone here called the Zoid Process. Zoid pro process remains cartilage for a |
|
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42:53 | long time. It's like when you in your late thirties or forties, |
|
|
42:57 | actually becomes solid bone. This is weird, right? So we'll get |
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43:04 | that in just a second. All , we're gonna start here with the |
|
|
43:11 | , remember? All right, now , I understand that none of you |
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43:17 | taken developmental biology, right? Anyone am I am I wrong? One |
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|
43:23 | , two people. All right. they talk about the development of the |
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|
43:27 | very early on from the? So the stuff like that? No, |
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43:32 | of just like words that sound So sounds, sounds familiar, doesn't |
|
|
43:36 | ? Right. So what we're dealing here, um and I'm really excited |
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43:40 | now I've got two people who may understand some of the words I'm gonna |
|
|
43:42 | . All right. So we are is called a Trib blastic organism. |
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|
43:45 | right, we start off single multiple cells, the cells divide into |
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|
43:49 | different groups of tissue, right? that's endometrium, sorry, not |
|
|
43:54 | excuse me, but backup, backup is reproductive. Um What is |
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|
44:00 | What is mesoderm? And what is and a lack of a better |
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|
44:05 | Ectoderm are things on the surface. is um uh structures that are um |
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44:14 | like the organ tissues. And then mesoderm, which is anything that's kind |
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44:19 | red in the body is the way always remember it, right? But |
|
|
44:21 | I wanna focus here is on the . All right. So again, |
|
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44:25 | don't need to know these three please, please don't sit there and |
|
|
44:28 | down it's mesoderm and I must know , right. One of the things |
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44:31 | mesoderm gives rise to is the All right. And the meeny is |
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44:38 | gives rise to these different types of tissues that we've described. And so |
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44:43 | represents this loose uh uh tissue that can be differentiated in a whole bunch |
|
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44:49 | different things. And so you can here, we got these Mazal |
|
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44:54 | there's fibers. So you can see a network of material there. And |
|
|
44:57 | happens is that some of these cells going to differentiate and they become |
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45:03 | meaning they're going to produce bone. so they're kind of together, they've |
|
|
45:08 | , they're creating these osteoblasts and what osteoblasts do? They start laying down |
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|
45:12 | ? And so they're laying down matrix it goes on all different sides. |
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|
45:16 | you can imagine um here, the of us were uh osteoblasts and you're |
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|
45:21 | down matrix, you're laying down matrix I'm laying down matrix. And what |
|
|
45:24 | start doing is we start pushing each away, right? Because I'm laying |
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45:28 | in all different directions. But then there's gonna be a point where I |
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45:31 | lay anymore and they can't lay And so I trap myself inside this |
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|
45:36 | , right? And so there you see, I've got an osteoblast that |
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|
45:40 | now trapped and it's going to become osteocyte. And then what happens is |
|
|
45:45 | matrix? Remember we said the matrix is primarily collagen starts getting salts. |
|
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45:51 | so part of building this matrix is these salts to it. And so |
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|
45:55 | is what traps those osteocyte, but what's on the outside blasts, |
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46:01 | They're still there. And so what doing is I'm still laying down matrix |
|
|
46:04 | dividing and I'm pushing this out. so I begin creating this structure of |
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46:11 | where I've got things that are but I still have cells on the |
|
|
46:14 | . And I'm laying down a network looks an awful lot, lot, |
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|
46:18 | that, that an awful lot like bone. Doesn't that kind of look |
|
|
46:22 | spongy bone? Now, it's not bone yet. It's doesn't have that |
|
|
46:26 | . But this is this woven bone what's happening because all I'm doing is |
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46:33 | just started just laying down matrix and building and pushing the mesen outward and |
|
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46:41 | away from this point of origin. at how the mesen is being compressed |
|
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46:48 | pushed away on either side in the cartoon. And so now I have |
|
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46:54 | osteo progenitor cells and I have osteoblasts are kind of getting stuck against that |
|
|
47:01 | . I've got cells that are stuck the network. I've got cells that |
|
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47:05 | stuck in the matrix and now what doing is they're starting to behave and |
|
|
47:11 | bone that we're more familiar with. while this looks like spongy bone and |
|
|
47:16 | got blood vessels penetrating in and providing and stuff, what happens is these |
|
|
47:21 | on the outside, begin to start bone like. So, so I |
|
|
47:26 | up with a layer of compact Now, what do you think this |
|
|
47:31 | out here? It's connected tissue. the name of it on the outside |
|
|
47:37 | a bone periosteum. So that meeny to compress and compress, compress and |
|
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47:47 | that periosteum on the outside. And I've got osteoblasts that are laying down |
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47:53 | bone. I got osteoblasts and some gender cells here maintaining the lay of |
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48:01 | spongy bone, which started off in less organized manner and on the outside |
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48:07 | , on this side, periosteum, osteoblasts. So this is how I |
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48:13 | this layer of compact bone that protects inner spongy bone does that kind of |
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48:22 | sense. So there's nothing on which building. It's just I'm starting inside |
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48:29 | matrix of tissue and I just start stuff and it arranges itself naturally, |
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48:36 | because it has a model, but cells just kind of get trapped and |
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48:41 | just do what they do as they're to do that kind of makes |
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48:48 | All right. So that's how we intramembranous growth. I'm inside a |
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48:55 | I build these structures and it gives to the shape that I'm familiar |
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48:59 | Compact bone Oreo, right? It's compact bone Oreo with spongy bone on |
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49:05 | inside. Endochondral begins when we build this cartilage skeleton. So here we're |
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49:18 | a uh uh a developing embryo, not an embryo at this point, |
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49:22 | ? A developing child where it has cartilage skeleton. That's what you're seeing |
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49:30 | . It's been stained. So you see where the skeleton is at |
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49:34 | right. And then what happens is that, that, that cartilage |
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49:40 | to have calcium laid on top of . And so what we're doing is |
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49:45 | osteogenic cells are starting to lay car lay calcium down, which causes the |
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49:52 | on the inside to be denied access their nutrients. So, when the |
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49:58 | is denied as nutrients, what does do? He dies? Right. |
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50:04 | I don't give you your food, gonna happen to you besides getting |
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50:09 | you're gonna die, right? It take a little bit of time, |
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50:12 | these are really, really active So think about being a teenager and |
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50:15 | denied a single meal. How horrible was, right. That's kind of |
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50:18 | going on here. They're like, we're gonna die. And so they |
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50:21 | and so these cells begin to And so what happens is, is |
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50:26 | progenitor cells start migrating into the area they take these cells that have died |
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50:31 | replace them with these osteopor genetic cells they start laying down matrix and then |
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50:37 | you end up with are these areas are going through this process of |
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50:42 | So you can see here, here's diaphysis would start off as cartilage and |
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50:48 | a small collar of bone, ultimately completely replaced by a bone. And |
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50:54 | down here in the epithets as blood penetrate through, we're gonna see the |
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50:58 | process occur. The cells are being access to uh their blood. So |
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51:04 | die off and you replace them with this osteogenic tissue which then starts laying |
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51:09 | bone. And what we end up is these areas at the end, |
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51:13 | epithets having bone. And again, gonna be the same sort of |
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51:17 | I'm gonna put compact bone on the because I'm being pressed outward and I've |
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51:22 | spongy bone on the inside. All . And so this is kind of |
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51:26 | we, where we end up when uh very, very young. So |
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51:30 | is when we're born roughly. Now we are just pre toddler. |
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51:34 | so we have areas of primarily but bone is starting to replace |
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51:38 | And then the central part of the is bone tissue, osseous tissue. |
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51:44 | , you heard me say a couple days ago, my horrible um truth |
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51:49 | my Children and how we just kind ignore them and let them free range |
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51:52 | fall off stuff and why? Because are primarily made of cartilage, they're |
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51:58 | and they bounce. You don't like idea, but they do. I |
|
|
52:03 | , I watch when, before I a kid, I watched one of |
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52:07 | friends', kids literally tumble down an step stairway. And the little |
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52:13 | it was a little girl, she, you know, she's a |
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52:16 | like younger than this, right? mean, we're talking a little bit |
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52:18 | than that and she looked up and mom wasn't there. So she was |
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52:23 | , I don't know if I'm supposed cry or not. And her dad |
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52:25 | at her and said, who's who's tough as nails? Hannah. |
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52:31 | she got up and walked away and right. We do the same thing |
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52:40 | looking for the, the pity response mama. So, in our |
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52:44 | that's what we do. No, pity. Just get up, dust |
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52:48 | off. Move on three days broken wrist, it wasn't a big |
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52:55 | wrist. One had to wear a . All right. So again, |
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52:59 | can start seeing here as you get , the epithets gets stronger. The |
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53:05 | is now starting to hollow out and starting to fill out that med |
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53:09 | But notice what we have here is region of cartilage that sits between the |
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53:15 | and the Diapy. Remember we call region the metaphysis, it contains what |
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53:19 | called the epithelial plate. And the plate is where you have actively dividing |
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53:27 | . All right, and is actively . Cartilage is what allows you to |
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53:32 | upward. So your long bones are themselves to expand because this area still |
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53:42 | dividing cells that are pushing the epithet from the diaphysis on both ends. |
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53:47 | your bone is getting longer and longer longer this way. At some |
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53:53 | you're gonna go through puberty somewhere between ages of 10 and 25 the bone |
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53:59 | in the diaphysis is going to grow than the cartilage dividing in the e |
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54:04 | plate and it will begin replacing those cells. And ultimately, it will |
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54:10 | up to the front end of those . And when it does, you're |
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54:15 | growing. So this happens differently for people. Some are late and will |
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54:22 | to grow until they're in their Some of you stop growing when you're |
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54:27 | to the age of 10. My daughter was so sad when she |
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54:32 | out that she wasn't getting any you know, she's 16 and she |
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54:37 | , she hit, she got her Burt and then she just kind of |
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54:41 | , right? My two younger sons are four years younger than her have |
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54:46 | caught up with her. And she's like, I don't wanna be |
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54:49 | she's not that short, but she's relative to her brothers. So this |
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54:58 | of growth where we're talking about the um epithelial or sorry, not |
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55:04 | epithelial, the epithelial plate. This of growth is what is called interstitial |
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55:10 | growth within the bone. All And so what's happening here is the |
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55:16 | that's nearest, the epiphysis has the cells. And what they're doing is |
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55:22 | laying cells downwards. In other they're growing, they're pushing this way |
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55:28 | laying cells that way, right? , I'm pushing downward. So I'm |
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55:33 | further and further away from the So I'm laying down cells driving this |
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55:38 | and this is why this gets bigger bigger and bigger. But we also |
|
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55:42 | osteogenic cells. And so the osteogenic are progressing upward and they're trying to |
|
|
55:48 | up to those growing cells, The way this happens, this happens |
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|
55:54 | puberty. So this is when you're your massive uh growth phase and the |
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55:59 | are bone cells are growing upward. ultimately, what they do is they |
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|
56:03 | up with these mitotic cells and they them to calcify and die. And |
|
|
56:08 | is I think what this picture kind looks like. So up here, |
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56:12 | this is the region of massive So these are the cells that are |
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56:16 | and what they're doing is they're dividing way so that the most active cells |
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56:20 | nearest up there. The least active are down here as you get further |
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56:26 | further from the active dividing stage, become hypertrophic and they eventually die. |
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56:31 | down here, these are the cells are the bone cells that are moving |
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56:35 | and they're taking over this region of . And so this is eventually going |
|
|
56:40 | get to a point where it's growing than that and catches up with this |
|
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56:43 | replaces all that. Now, think a little kid and think about the |
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56:53 | of their arm like that, And I think of the size of |
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|
56:57 | arm is your arm that then or it like this fatter? Right? |
|
|
57:08 | . So you don't just grow along edges, you don't grow just in |
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57:12 | direction, instead, you also grow and this is a oppositional growth, |
|
|
57:17 | ? So, remember we have the , we have the endosteum and those |
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|
57:20 | osteo progenitor cells and osteoblast and they're down bone. And so as they're |
|
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57:25 | down bone, the bone is getting and thicker and thicker and thicker and |
|
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57:28 | it does that the bone gets heavier heavier and heavier and heavier. So |
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57:31 | body is like, I don't want carry that much weight. What I |
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57:33 | do is I wanna break down bone the inside and so on the |
|
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57:36 | it's basically breaking down bone. So lattice work, that's that spongy bone |
|
|
57:41 | there is also breaking down. And it breaks down, what ends up |
|
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57:46 | is that the rate at which it down is much slower than the rate |
|
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57:49 | which it's building. And so what end up with is a bone that |
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57:52 | thicker and thicker and thicker, but make a larger cavity on the |
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|
57:56 | So your bone gets wider, Because you're growing this direction and as |
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58:02 | grow up, your bones are getting , so they get bigger and |
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58:06 | Appositional is wider. Interstitial is It kind of makes sense, but |
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58:18 | not just doing it on one we have to make that hole that |
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58:22 | cavity larger. All right, pausing for a second stretch. Your brain |
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|
58:32 | up, look down. Look Look right. Are there questions about |
|
|
58:36 | two things? No one has a of why are girls shorter than guys |
|
|
58:43 | the average? Oh, there is question. Well, I haven't heard |
|
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58:48 | yet. Yes. What a good . Yeah. Oh, man. |
|
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58:59 | right. So as you're well men and women or boys and girls |
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59:05 | in a puberty at different times, ? Girls enter puberty at an earlier |
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59:11 | than boys do. Guys are very with this because at summer we go |
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59:15 | in sixth grade or fifth grade, come back, all the girls are |
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59:18 | and all the guys are basically all same. But all the guys know |
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59:22 | girls are walking around like oh girls shapes now, right? We're very |
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59:26 | about that. We don't know why excited about it, but we just |
|
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59:29 | and then we figured it out about years later. All right. But |
|
|
59:33 | that means is is that the growth , pubertal growth spurt occurs earlier. |
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|
59:38 | you can imagine. I've got I've got a boy and a |
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59:40 | twin, right? So my daughter my son were roughly the same |
|
|
59:45 | right? And they're growing and then daughter hits her growth spurt. |
|
|
59:50 | notice, did my son stop No, he's just not growing as |
|
|
59:54 | . And so she goes through that spurt earlier, but because of the |
|
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60:00 | plate closure, she stops growth at certain point and then my son hits |
|
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60:06 | and then he goes through his growth and then his EHES plate will |
|
|
60:12 | He hasn't stopped yet. It's very frustrating because he's taller than me |
|
|
60:17 | . He's 16. Drives me Dad. How tall are you? |
|
|
60:24 | right. But that's the reason why , when you enter in to |
|
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60:28 | it's like giving yourself, um, a head start because what's happening is |
|
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60:34 | it's a race, ladies, you're the race earlier and then you're running |
|
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60:38 | of fuel, whereas guys are walking they start running and then they get |
|
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60:45 | run. So they get to go . Second thing, estrogen increases the |
|
|
60:51 | at which the epithelial plate closes. right. So it's, that's just |
|
|
60:56 | of the bargain, right? So get closure of the epithets plate earlier |
|
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61:01 | guys do because we don't have as estrogen in our bodies. So they |
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61:06 | doing. So you saw that age it said two, the age |
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61:09 | You remember on that said from 10 about 25. So way back in |
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61:13 | day, um I worked for the program and so I was a tutor |
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61:21 | students pass their math classes and their classes. And I remember one time |
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61:26 | four freshmen in an elevator in the . So here I am in my |
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61:32 | ft whatever. And I have a who's six ft 86 ft 76 ft |
|
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61:37 | and six ft 10 in the elevator me. Right. I'm like in |
|
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61:42 | tree of, you know, and freshmen and they're not, they haven't |
|
|
61:46 | growing yet. So, you one of them, I think it |
|
|
61:49 | ended up being seven ft one playing Europe. Right. So those growth |
|
|
61:55 | can continue on for a long Man. That was so weird. |
|
|
62:06 | . How are we feeling so Yeah, they can be taller. |
|
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62:15 | . So that doesn't mean that all who are taller have started earlier or |
|
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62:19 | later just means the epithelial plate um, hasn't closed. So, |
|
|
62:25 | of the things that you, if take me in a P two ever |
|
|
62:29 | in and we'll, we'll talk about a little bit. Um, but |
|
|
62:32 | speaking, uh, puberty is one those really weird things. Uh, |
|
|
62:36 | , we keep saying, oh, starting earlier and earlier and that's not |
|
|
62:39 | . It's, it's, we've, come to understand when it starts a |
|
|
62:44 | better, but the idea here is are, your height is dependent primarily |
|
|
62:49 | several factors. Genetics is one, ? I mean, if you have |
|
|
62:53 | short parents, what's the probability you're be tall? Not very, |
|
|
62:57 | you're probably gonna be short as but it's nutrition, right? |
|
|
63:02 | so if you eat well and so, uh, we have a |
|
|
63:05 | who has two tall kids, one short kid, the short kid never |
|
|
63:10 | , uh, to, uh, learned to have an adult palate. |
|
|
63:14 | all she does to notice there's she first, but all she does |
|
|
63:18 | eat like pizza and blo cheese sandwiches she doesn't eat food that would be |
|
|
63:27 | to growth. Right. So, your vegetables, kids is, is |
|
|
63:32 | other thing. And then, another thing is being free from disease |
|
|
63:37 | free from, um, stress and like that. That's another factor that |
|
|
63:42 | an important role in growth. I a question there and I've been |
|
|
63:45 | Yeah. Go ahead. It, could, right? And again, |
|
|
63:54 | part of it is is the timing that closure. So if you're going |
|
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63:59 | a massive growth spurt, which is response to all these other factors, |
|
|
64:03 | gonna go quickly. But the estrogen , if they're, if they're higher |
|
|
64:08 | stunt a person's growth. But so androgens. I mean, one of |
|
|
64:14 | things they tell you is when you're a young, young man is you |
|
|
64:18 | not go and lift weights before your is ready to do. So because |
|
|
64:22 | can stunt your growth when you start in all these hormones or start producing |
|
|
64:27 | androgenic hormones that make you stronger, may keep you squat as well. |
|
|
64:33 | , so the other one. Mhm mhm So this is a really |
|
|
64:53 | question, right? Because I'm, at that point now where I feel |
|
|
64:56 | and I just want to sit around , but that's not a function |
|
|
65:00 | I'm old and I can't do. more a function of, I don't |
|
|
65:04 | do. All right. There's, a difference. Right. So, |
|
|
65:08 | know, one of the things that we, we just presume is |
|
|
65:11 | the older you get, the less you become and, and the other |
|
|
65:15 | is that your metabolism slows down. was a huge study that was released |
|
|
65:19 | four months ago, five months ago they looked at you like hundreds of |
|
|
65:23 | of people data from tons and tons studies. And what they found was |
|
|
65:26 | metabolism doesn't change over the course of life. It actually stays relatively |
|
|
65:32 | What happens is, is we become because, well, I'm just gonna |
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|
65:37 | the word we're lazy. I if I have the choice of sending |
|
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65:40 | son out to my yard instead of , guess who's going out, you |
|
|
65:44 | , I'm bigger than him still. so I can make him right. |
|
|
65:48 | , but truthfully it's, it's it's more of an attitude thing. |
|
|
65:53 | , like, you know, I'm gonna pick on grandma for a |
|
|
65:56 | , right? I mean, grandma frail. Grandma is not as strong |
|
|
65:59 | she used to be, you oh, her bones are getting weaker |
|
|
66:03 | the loss of estrogen no longer supports bone growth, you know, so |
|
|
66:06 | the osteo um too many Oscar words my head right now. Um And |
|
|
66:16 | not using the right one I'm thinking , which is something completely different. |
|
|
66:20 | , um, osteoporosis is the word looking for. So it's like they're |
|
|
66:24 | . No, no. What, you do is as you work |
|
|
66:28 | and do the things that you do bones as well as your muscles will |
|
|
66:34 | and be able to do that. don't want to overstress them. In |
|
|
66:37 | words, you don't want to ok. Um, grandma, I |
|
|
66:39 | you to go out and I want to start, um, you |
|
|
66:43 | I don't know, lifting logs, mean, that's, that's unnecessary, |
|
|
66:47 | ? But if she goes and moves thing and then the next day she |
|
|
66:50 | and moves another thing, her body gonna say, oh, this is |
|
|
66:52 | that you regularly do. So it's to strengthen the muscle on the bone |
|
|
66:55 | make that happen. This is why workouts are important, right? Because |
|
|
67:00 | they do is they create a constant of stress, not over stress, |
|
|
67:04 | just a state of stress to strengthen , you know. So what would |
|
|
67:11 | say? Eat your vegetables and also forget to work out, you |
|
|
67:16 | doesn't have to be a lot. don't have to, no one, |
|
|
67:18 | everyone has to be benching 300 you , squatting six, you know, |
|
|
67:24 | do enough, do that kind of the question a little bit. |
|
|
67:28 | Yeah. Yes, ma'am. You're have to speak up a little |
|
|
67:37 | How, how are they flexible that to do. So, the thing |
|
|
67:40 | not talking about when we're talking about skeleton is talking about ligaments, |
|
|
67:44 | So flexibility is in the structure of ligament itself, right? So um |
|
|
67:53 | so collagen and other fibers are there form these ligaments and there are different |
|
|
67:59 | of collagen, there are col collagen have greater flexibility than others. And |
|
|
68:04 | some of us actually have that greater because the collagen in our body builds |
|
|
68:09 | actually unique and different and gives that degree of flexibility. So that's, |
|
|
68:14 | part of it also, it's using those structures as well. |
|
|
68:19 | um you've probably seen people who do are particularly flexible. Why? Because |
|
|
68:25 | day they stretch, right? And basically say these are the movements my |
|
|
68:29 | has to make you look at someone me that looks at yoga and |
|
|
68:32 | is that a food or is that exercise? Because yoga, yoga, |
|
|
68:37 | know, close. Um I I'm not flexible, you know, |
|
|
68:41 | there are days when I'm like get the shower, I'm like, I've |
|
|
68:43 | to just touch my toes because, know, get that hot water on |
|
|
68:46 | back because it's I I I'm just and sore all the time. So |
|
|
68:51 | has to do with, with the portion, not the bone portion of |
|
|
68:55 | skeleton, anything else? Yeah. Just any sort of work, anything |
|
|
69:09 | causes you. So, when we about the skeleton, you, you |
|
|
69:12 | keep in mind that it's really muscles skeleton working together, right? So |
|
|
69:17 | sort of stressor you put on the , right? So when you lay |
|
|
69:20 | the bed, you're putting a stressor your bones, right? You're putting |
|
|
69:25 | in a particular direction. So your has to, to deal with that |
|
|
69:30 | . Now, I'm not saying laying is like, oh please everyone lay |
|
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69:33 | and that, you know, that's just in one direction, |
|
|
69:36 | If all you do is lay then your body is gonna say I |
|
|
69:38 | don't need to create enough strength so my body doesn't collapse on itself. |
|
|
69:47 | No, no, you're absolutely strengthening think about you pulling yourself through |
|
|
69:51 | through the water, right? Moving water is much more difficult than movement |
|
|
69:55 | air, isn't it? Right? pulling your, you're pulling your entire |
|
|
70:00 | in a, in a medium that resisting your movement. I mean, |
|
|
70:03 | resists our movement as well, but all around us. So when you |
|
|
70:07 | in the water, you're actually fighting it. So you're strengthening your |
|
|
70:12 | right? But you're also strengthen the that are being pulled against because movement |
|
|
70:17 | really your muscles pulling and changing the of your bones. It's kind of |
|
|
70:22 | . Huh? Yeah. Yeah. is one of the reasons why we |
|
|
70:26 | that because it is low impact, ? You're not, you know, |
|
|
70:30 | it. So we get little old again. I'm using little old ladies |
|
|
70:34 | guys aren't gonna do this. but they go down to the y |
|
|
70:37 | all get into the pool and they stay in the pool and they do |
|
|
70:40 | aerobics. Right? Why? Because low impact. It allows them |
|
|
70:44 | to meet that resistance and it makes muscles stronger and their bones stronger. |
|
|
71:01 | . Yeah, because so, so idea here is, you know, |
|
|
71:06 | , we there like my son, was when he was 10, while |
|
|
71:09 | wanted to start lifting weights, I'm , no, no, just, |
|
|
71:11 | be a boy. You go do like if you lift your body into |
|
|
71:15 | tree that's like lifting weights, But the idea here is when you're |
|
|
71:19 | through and your body is trying to itself like in early puberty, then |
|
|
71:24 | you're gonna do is you can have impact on how it's building itself by |
|
|
71:29 | lifting, you know, and doing that the body isn't quite designed to |
|
|
71:34 | yet. Right? I mean, about, think about a, like |
|
|
71:38 | eighth grader or 1/9 grader, I mean, that's when you're really |
|
|
71:41 | to see the male form starting to , right? Boys actually start doing |
|
|
71:45 | guys. Remember everyone's checking out each pecks, like check my picks |
|
|
71:50 | you know, it's like, you can list £30. But |
|
|
71:53 | you get, you start getting that . So that's when you probably wanna |
|
|
71:56 | doing because now your muscles have actually through that, that thing that, |
|
|
72:01 | reconfiguration to be able to do the that men, male bodies are designed |
|
|
72:06 | do. And when we go down rabbit hole hole, it's, |
|
|
72:11 | it's crazy. You guys ready to talking about Dan bones and bones and |
|
|
72:17 | . All right. Um, I know how far we're gonna get. |
|
|
72:22 | Usually when I give this lecture in regular semester, it's like this is |
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72:25 | one class, you know, so an hour and 20 minutes and I |
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72:28 | I usually get done in an So we may not get through all |
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72:30 | bones, but we have the joints and the joints are really easy. |
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72:34 | , um so if we don't complete stuff today, we'll continue on |
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72:38 | And, and again, when when we started this class at the |
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72:42 | of the semester, last week, like, hey, there's two parts |
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72:45 | your body. You have the AEN or the appendicular region, you have |
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72:50 | axial region and the, the skeleton the same thing. We have an |
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72:54 | skeleton which you can see here is in blue. It's basically the ax |
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72:56 | the body. It includes the the vertebral column, the vertebral |
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73:01 | I sound terrible, the ribs. And um that's about it. And |
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73:06 | everything else is appendicular. And so includes the girdles So the girdle includes |
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73:13 | hips and your shoulders as, as as the long bones of the arms |
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73:17 | the phalanges at the end. All . So the way you think about |
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73:22 | axial skeleton plays a role in caring supporting other body parts. So it's |
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73:27 | , whereas the appendicular skeleton is primarily in locomotion. All right. That's |
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73:34 | just a dance that's movement in OK. And I didn't mention there's |
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73:40 | like 200 some odd bones in But what's in saying that one? |
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73:44 | kind of to say, look at end of this, you can pat |
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73:47 | on the back and say, I can memorize 200 things, you |
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73:49 | , it's not, not a Um But really, it's, it's |
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73:53 | kind of give you the sense that , there really isn't as many as |
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73:56 | sounds like. All right. So we do is we start with the |
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74:01 | , the skull, there are 22 here. And so you can think |
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74:05 | the skull as having two parts. have our cranium and we have our |
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74:09 | . All right. So the cranium has about eight bones, the facial |
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74:13 | , there's 14 of them. But , many of these are gonna be |
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74:16 | . So the actual numbers are a less. Now, these are primarily |
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74:20 | bones. All right. And the of joint that they're gonna have is |
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74:26 | a suture. And so we're gonna a, a first type of joint |
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74:30 | , I think someone asked me a about these. Uh yesterday, I |
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74:33 | like, what, what are those ? Well, they're, it's just |
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74:36 | , it's just a type of joint it's referred to as the suture. |
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74:39 | so these are um uh interlocked and it prevents the bones from moving. |
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74:44 | so this is um uh basically your in and of itself is actually a |
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74:48 | , very protective structure. It's for the most part immobile, with |
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74:53 | exception of one bone, which is mandible, that's what sits at your |
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74:57 | of your jaw, right? So gonna start with the cranium and very |
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75:02 | what you'll see is you'll see just views, but the slides may be |
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75:05 | same. So it, it will by pretty quick. Um your |
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75:10 | Uh Well, let me put this , your test, what I'll probably |
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75:13 | is throw you a picture like That's even color coded just to make |
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75:18 | lives easy, right? The they will never do that. I |
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75:21 | , they might, I don't I don't do the lab, |
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75:23 | But your homework won't have stuff like . It will actually having you like |
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75:27 | so you can try to see the . All right. So I'm just |
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75:30 | to give you guys a little bit a leg up on the, on |
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75:32 | lab stuff. But the test for purposes, I'm gonna just keep it |
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75:36 | really simple, just something that's color and you may get a view like |
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75:41 | or a view like that or a like that. All right. So |
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75:45 | regard to the cranium. All we got a couple of bones. |
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75:48 | have the bone in the front. is the frontal bone shocking, |
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75:53 | One in the front frontal. All . Then back here in the |
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75:57 | that's the occipital. All right. are all those are single bones, |
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76:02 | right. And then we have this that's really, really hard to see |
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76:05 | you look from the top. You see it only makes a small portion |
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76:08 | the cranium, but it goes down and makes up the walls of the |
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76:13 | cavity. This is called the ethmoid then the bone that's next to the |
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76:18 | . That kind of looks like a or a butterfly. What do you |
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76:20 | ? Bird, butterfly, bat, , you got bat, right? |
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76:24 | look at it, I see a but I I I see the bat |
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76:27 | ? But this this this bone that kind of has this weird shape |
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76:31 | is called the sphenoid. So we frontal occipital, we have ethmoid and |
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76:37 | on the inside that looks like the , that's the sphenoid. So |
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76:41 | feno, all right. So those the four single bones, all |
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76:46 | And then we have two pairs of . We have the temporal bone, |
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76:55 | right, that sits over here on side of the cranium, right, |
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76:58 | called the temporal because temporal means right. And the first signs of |
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77:09 | his gray hair over here on the of your head, that's where it |
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77:12 | its name. So temporal bone, region and we call it the |
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77:17 | right? Oh I got temples And then on top, we have |
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77:22 | pair of bones here. So two bones and a pair of bones up |
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77:25 | . Those are the parietal, So frontal occipital pair of parietal pair |
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77:30 | temporal, we have the ethmoid and we have the feno that sits on |
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77:35 | inside. You can see it All right. Now, if you |
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77:38 | about the cranium itself, there are parts to it. We have a |
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77:42 | which we refer to as the cranial . You can see the cranial base |
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77:45 | and then we have the round part the top, the helmet portion that |
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77:49 | the vault. So again, you kind of see which parts make up |
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77:54 | . So this total portion right that's a vault. So the idea |
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77:58 | is everything in the in the It is gonna be the frontal, |
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78:01 | parietal and the occipital parts of the , the floor then is gonna be |
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78:06 | parts of the occipital, primarily, primarily uh some frontal, a little |
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78:12 | of Etno, a little bit of . Now, if you look at |
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78:19 | bottom, you know the base, cranial base. What you see is |
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78:23 | there's like three little shelves. All , you can't really see it in |
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78:27 | way. But with get cut away , here's a shelf there, shelf |
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78:30 | , shelf there. Now, what looking at there is we're looking at |
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78:32 | brain and the cerebrum. So that's cerebrum and the cerebellum, this is |
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78:35 | cerebrum, that's cerebellum down there. brain sits on the base, not |
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78:41 | , there's fluid and stuff in the , but basically these shelves cradle and |
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78:46 | the, the brain. And so has this unique shape because of the |
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78:52 | of the brain or vice versa, came first. So the part in |
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78:57 | front right here, that would be anterior FASA, it's made up of |
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79:02 | frontal, the hyoid and the Then we have the middle fossa which |
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79:07 | portions of the feno but primarily temporal . And then the rear is parts |
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79:14 | the temporal bone. But for the part, the posterior fossa is made |
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79:17 | of the occipital bone. That kind makes sense. So we're just think |
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79:24 | the base as holding stuff. And you can kind of see the different |
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79:27 | and you can kind of mis match as you go. All right. |
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79:31 | last thing I want to point out with regard to the base, there's |
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79:35 | big giant gaping hole, name of hole, the big hole frame, |
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79:42 | Magnus, all right, frame and is there to allow for the passage |
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79:47 | the spinal cord. So coming out the bottom of the brain is the |
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79:52 | cord and it extends downwards. So what the big hole is for. |
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79:59 | going to come back to joints like said tomorrow. But I just want |
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80:02 | point out these joint, these are joints. They don't allow, you |
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80:05 | sit there and play with them. brain is not going to move |
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80:08 | your head is not going to move . Those bones are basically cemented together |
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80:12 | these joints. These are called The sutures, the big, the |
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80:16 | sutures are here. We have the . Remember how we said the colonel |
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80:21 | is the statue of Liberty Crown, ? So the coronal suture goes across |
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80:27 | . It separates the frontal from the parietal. OK. So that's that |
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80:32 | and you can see it right here the top. All right, we |
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80:36 | the lambdoid suture. What's a It's a Greek L, right? |
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80:43 | it looks like this. If it's case, if it's upper case, |
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80:46 | looks like that, right? That sense. So, do you see |
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80:50 | we got here? It's not quite lambda. It's a lambdoid, it's |
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80:55 | . So that's where you got its . All right. Remember we cut |
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80:58 | in half. That's the sale So the suture that goes down through |
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81:02 | middle between the two parietal. That's Sagi suture. OK. And then |
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81:07 | got the weird one. I don't why they came up with this |
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81:11 | but it's Squamous. What does Squamous scale? Like it's like flat, |
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81:15 | guess. All right, fine. sits between the prial and the |
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81:19 | So there's the Squamous. OK. those are the sutures you need to |
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81:26 | . And I, someone asked I guess you're not here today about |
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81:30 | bones. There's examples of sesame bones in there. So we don't need |
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81:35 | know them. I'm just pointing them to you. So sutures does make |
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81:41 | . Coronal sagittal lado squamous, you do that in the test. You |
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81:57 | , if you see someone doing that , just, just giggle to yourself |
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82:03 | out of the face, you can why this goes fast because me pointing |
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82:07 | a picture. All right, we two single bones. I'll just point |
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82:11 | out right now. So this is mandible. It is a single |
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82:15 | It's formed by as a single bone then inside your nose, it divides |
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82:21 | nose into two halves. So that be the septum. There's a bone |
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82:25 | that's called the bomer. And you see from a cross section there, |
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82:29 | is in the middle, see that then over on the other side. |
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82:32 | on the, on the outside wall that nasal cathode, that would be |
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82:35 | ethmoid. All right, in terms the paired bones, remember that hard |
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82:44 | up here. That's the nasal All right. I'm just gonna look |
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82:47 | this here. All right. On inside of the orbital cavity right |
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82:53 | All right. That is the lacrimal on either side. Ok. When |
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82:59 | think of lacrimal, you should be tears. That's where the tear duct |
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83:02 | actually located. Tears aren't made They just collect there. You |
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83:06 | when you're sad or happy or we need a good cry. The next |
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83:14 | the Zygomatic bone. Aaron point to cheek. There's your Zygomatic bone. |
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83:19 | right. You got two of All right. Uh Entine, the |
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83:23 | bone is way back in the back your mouth. All right. You |
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83:28 | how, when you're feeling really, horrible and you're sitting there in front |
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83:31 | the toilet and you're like, I , I just got to throw |
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83:33 | So what do you do? You push the trigger? All right, |
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83:36 | like, all right before you get the trigger, right? There's a |
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83:44 | palate, right? So the pines not where the, the front part |
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83:53 | the hard palate. It's the back of the hard palate. OK? |
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83:57 | there's two of them, there's one either side. If you think of |
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83:59 | body being divided in half, it's back there. All right. The |
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84:04 | is the maxilla, which looks like big giant bone. But if you |
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84:08 | carefully right there, you can see is a seam that was two bones |
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84:11 | of grew together and forms this front right here. So it's your upper |
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84:16 | . But it also makes up the part of the hard palate separates the |
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84:22 | cavity from the um uh the the cavity and then on the inside. |
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84:30 | so this is the only place where gonna see a good picture of |
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84:32 | So it's inside here, inside the cavity, you have the inferior nasal |
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84:38 | and so they're kind of little tiny that kind of stick out from the |
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84:42 | and create these turbinates. So what do all these things do? |
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84:46 | , they form the cavities of your senses. That would be your |
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84:50 | your smell, your taste, so , smell, taste turbinates air. |
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84:54 | as air is breathed in, it to move like. So because of |
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84:58 | in uh inferior nasal concha creates an for the air as well as for |
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85:05 | . You can see here with the and the mandible secures your teeth. |
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85:07 | it also serves as these structures serve to anchor all the facial muscles to |
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85:15 | skull. So just know the bones where they're located. So this is |
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85:24 | a different view. So you can much more clearly. Here's the vo |
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85:27 | are the nasal con, you can the palan, the max, it |
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85:32 | you a better sense of where those are located, right? I think |
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85:36 | may have one where you can actually your, like in the book and |
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|
85:39 | can kinda to turn things over and and look at it. But the |
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85:42 | way to explore this stuff is to go into the lab, pick up |
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85:46 | and talk to it like you're a person and then turn it over and |
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85:49 | with it. Now, there are couple of cavities in the skull. |
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85:54 | have the cranial cavity that's going to the largest uh cavity and that's going |
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85:57 | surround the brain. We have the cavities, that's where your eyeballs |
|
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86:01 | It has blood vessels, muscles and . There's actually even um for. |
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86:07 | this is the form that's fora that these uh nerves and blood vessels to |
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86:12 | through. Also has a point for lacrimal glands to go into the nasal |
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86:18 | . And in terms of the structures are formed there, you can see |
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86:21 | here is the frontal lobe uh back . This, well, let me |
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86:25 | sure I get this right. There's lacrimal um Here is the Zygomatic and |
|
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86:30 | the green one right there is, a lacrimal and this is part of |
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86:33 | maxilla. Um And let's see what I missing? Oh Palan, which |
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86:37 | can't see which is gonna be on back side. But that forms that |
|
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86:45 | , nasal cavity. Again, we do cut through. You can see |
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86:48 | , Bomer, Palantine maxilla on the Etno, we also have inside that |
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|
86:54 | saw from the inferior view, the uh the inferior nasal concho oral |
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87:01 | this is gonna be uh for Uh We also can breathe through much |
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87:06 | food. So we have the max the uh mandible are the primary |
|
|
87:11 | But also don't forget that we have pas there in the back as |
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|
87:15 | which is not listed on the When you say your sinuses or you |
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87:22 | a sinus infection. what a sinus sinus by definition is basically a |
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|
87:28 | What this does is it lightens the . So it's actually a, a |
|
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87:32 | space inside the bone. That's what little color coded regions are trying to |
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|
87:37 | you is which bone it's actually located just their name based on where they're |
|
|
87:42 | . So frontal, ethmoids, feno the maxillary sinus, but it lightens |
|
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87:49 | space. It also allows when you in since it's gonna be open to |
|
|
87:53 | nasal cavity, air goes into that it warms up before it gets pulled |
|
|
87:58 | into the lungs. It also becomes more humid. Um These are gonna |
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88:03 | mucus lined. And so you can like when you have an infection, |
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88:06 | happening is your body's producing all this to kind of wipe out and clear |
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88:11 | the in the infectious agent, which why you get all popped up and |
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88:15 | feel all horrible. It also creates or uh uh to your voice. |
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88:21 | you noticed that we all sounded different we don't sound exactly the same part |
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|
88:25 | that is because of the resonance that produce when we make sound. It's |
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88:29 | going into those, into that You know, and it causes the |
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88:33 | to vibrate and it's just makes us create that unique sound. So that's |
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88:38 | resonance in our voice. So, many bones have we learned so |
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88:47 | 22 out of 210% of the way moving down the neck, we have |
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88:56 | bone. It's called the hyoid It's associated with the larynx. You |
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89:00 | see right here that there is the , it kind of sits on its |
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89:03 | . It's not attached to any other in the body. It's actually held |
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89:06 | place by a series of ligaments and , two features to this. So |
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89:12 | you swallow, it moves up and , but two features is it has |
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89:15 | , these projections, one is called lesser horn and it has um ligaments |
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89:21 | which or muscles to which they're And then this is the greater |
|
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89:25 | So here's the ligament you don't need know the styloid stylohyoid, stylohyoid. |
|
|
89:32 | just notice whenever you see these they're just telling you what they're attached |
|
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89:36 | . That's, it's really how the works. So if you ever get |
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89:40 | of confusing attached to the stylus attach to the high bone. |
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89:46 | but don't worry about the name right and then there's bones, I |
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89:49 | muscles to which these are attached, ? It helps you in terms of |
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|
89:54 | . That's the whole purpose of Whenever you have a bone, a |
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89:58 | is there a muscle to pull, on. And that's what it's doing |
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90:01 | . Swallowing and speech. How many , how you burned every night? |
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90:10 | . Ok. I'm gonna keep asking . All right. Vertebrate. We |
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90:13 | a whole bunch of them. All . So there are five divisions. |
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90:17 | you look at them, they all in kind of a different way. |
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90:20 | you can see here there's different right? So, in terms of |
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90:25 | different groups, we have seven cervical , we have 12 thoracic vertebrae, |
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90:30 | lumbar, five Sarel and ultimately four . All right. So you can |
|
|
90:35 | up there seven. Now, here's weird thing. Do not write this |
|
|
90:38 | . Do not memorize this. I'm showing you how screwed up the world |
|
|
90:42 | . Truthfully, the majority of people the world have seven cervical vertebrae, |
|
|
90:46 | some of us have eight. About we see. We have 50 people |
|
|
90:50 | this class. Six of you likely eight cervical vertebrae, about 30% of |
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|
90:57 | population. That weird. So Actually. That's not right. It |
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91:06 | be six, 30% of 50 Yeah. See everyone's unique. It's |
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|
91:18 | . All right. How do I how many bones are each in these |
|
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91:23 | ? Do I sit there and What do you do. And |
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91:28 | oh, you're so smart. I it. Everyone listen to her. |
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91:33 | do normal people eat breakfast? Notice had to use the word normal because |
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91:36 | guys probably didn't eat breakfast this What time do normal people eat |
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|
91:41 | Seven AM. When do normal people lunch, noon when the normal people |
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91:46 | dinner? Five and then they have and then you wake up in the |
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91:53 | of the night. And what do have a snack at four? See |
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91:57 | it works. You'll never forget I'm glad you remember that. |
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92:01 | that's how I learned it. So the same thing for you. |
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|
92:04 | what I wanna point out is when were born, you were shaped like |
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92:06 | letter C, right? Your spine shaped like the letter C but you |
|
|
92:11 | longer are shaped like the letter Instead what you have is you have |
|
|
92:14 | series of curvatures, concave convex, , convex. And then this one's |
|
|
92:19 | of weird. All right, that's your remnant tail. It could |
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|
92:24 | longer. It shouldn't be. Um you know, when you say I |
|
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92:29 | my tailbone, that's what you're breaking there. The little cox. All |
|
|
92:35 | , Sarel and Cox, these are . So that's basically it's gonna appear |
|
|
92:40 | one bone. These are gonna appear one bone right now. Why does |
|
|
92:45 | spine curve because it makes you more a spring? Um Anyone here ever |
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|
92:50 | ? Uh nature shows ever? Do ever watch this nature show with a |
|
|
92:55 | ? Watch Cheetah Chase down one of little tiny fast gazelle. And what |
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92:59 | do, it stretches out and stretches out and squishes when it's |
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|
93:03 | It's like, well, that's what do when you walk. Right. |
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93:08 | basically are a spring and what this is the force of bearing your weight |
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93:13 | on this because you do weigh a for your spine. What it does |
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93:17 | it puts the weight in different And so the weight doesn't go straight |
|
|
93:23 | , it's being dispersed in different So you don't bear as much weight |
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93:27 | you normally would. And that's why acts kind of like a spring. |
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|
93:31 | right, gives you a lot of . All right. So we know |
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93:36 | are 7 12, that's 19 plus , 29 plus four. That's |
|
|
93:42 | So 23 plus 23 it's 46 bones we've talked about. Let's take a |
|
|
93:46 | at the different vertebrae. All So the different vertebrae all have a |
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|
93:52 | shape to them. All right, general shape is simply this, we |
|
|
93:58 | a body, right? So this the thing on which all the vertebrae |
|
|
94:02 | built. So you can see your , body, body body, they're |
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|
94:04 | stacked on top of each other. this is putting bone on top of |
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|
94:08 | and in between each of these we're gonna see an in intervertebral disc |
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|
94:12 | disperse some of that weight. All , but not only do we have |
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|
94:17 | body, we're gonna have these projections ultimately form a for a what is |
|
|
94:24 | for a, it's a hole and spinal cord is going to travel through |
|
|
94:31 | hole. So notice the spinal cord not the vertebrae, the spinal cord |
|
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94:35 | next to the vertebrae. It's protected the vertebrae. So the purpose of |
|
|
94:39 | bone is to protect the spinal And because this is a hole between |
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94:44 | the bones, you can see it this tunnel, it's flexible and so |
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|
94:48 | spinal cord is can move around in flexible space. This frame is formed |
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|
94:55 | what is called the vertebral arch. a composite structure from the different extensions |
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95:02 | you see working around. All we have peta calls the pentacles are |
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95:07 | portion and this right here are the . So there's lamin on number |
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95:11 | lamina, number two, that is forming the arch. OK? |
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95:17 | the arch which creates the, which next to the body, we still |
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95:21 | all these weird things that are going in different directions. Where are the |
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95:24 | things? These are called processes? right, if you feel on your |
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95:29 | , do you feel the bump, bump on your spine? You feel |
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95:33 | that is the spinal process? That's the part that's sticking outward. |
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95:39 | right, then we have two processes extend this direction, all right, |
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95:47 | , so they poke outward and then you can't see real well is below |
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95:54 | transverse process. And above on the side of the transverse process, we |
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95:57 | two more processes is to call the process. When you see the word |
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96:02 | , that is for an articulation, is the fancy anatomy word for saying |
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96:06 | joint. Ok. So the superior articular process articulates. So there's a |
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96:18 | , one articulates with the inferior articular of the vertebrae above it. So |
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96:26 | have a superior and an inferior. on the other side, you have |
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96:29 | superior which is articulating with an And this is how the different vertebrae |
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96:34 | interacting with each other. That kind makes sense. So that's how they're |
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96:39 | like so and they're interlocked. And I mentioned in between each of the |
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96:47 | of the vertebrae, you have these intervertebral discs. Your book is the |
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96:50 | book I've ever seen that actually shows in perfect condition. This is what |
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96:53 | supposed to look like. You can on the outer portion, we have |
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96:57 | really, really thick fibrous region, called the annuus fibrosis. And inside |
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97:01 | have the squishy reach region that is flexible, it's called the nucleus |
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97:06 | If you've ever had the shoe you know, the gel inserts, |
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97:10 | can think of it like that on outside, you can step and it |
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97:13 | the pressure that's outward So the forces are being applied downward are being distributed |
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97:20 | from that pressure. So, distribute some of the force. But |
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97:26 | you tear that annuus fibrosis, what end up with is that nucleus pulsus |
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97:33 | outward. And in this particular this is a herniated disc. In |
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97:38 | particular case, it's impinging upon the cord and causing a great deal of |
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97:45 | and distress in this particular individual, ? So this herniated disc is a |
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97:49 | of the annuus pulsus, allowing the or annuus fibrosis to allow the nucleus |
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97:54 | to to escape outward. That's what hernia disc is, right. But |
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98:00 | discs basically uh a pad of cartilage distributes force away from the vertebrae. |
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98:08 | , I'm showing you this not to , I'm showing you this to show |
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98:11 | that it doesn't matter where you are vertebrae have different shape, but they |
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98:15 | contain that same sort of structure. for example, you can see here |
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98:20 | processes, you can see the transverse , there's a spinous process. This |
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98:24 | be what the cervical region looks like here. This is kind of what |
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98:28 | already look like. This is But when you get down the lumbar |
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98:31 | notice here that the transverse processes aren't broad, but the spinous process is |
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98:36 | broad, right? Or it's And you can see here differently shaped |
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98:41 | articular processes. Do they all have body? Yeah. Do they all |
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98:47 | an arch, you know, do all have a yes. Do they |
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98:51 | have the spine or the different Yes. So, yes, |
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98:55 | Yes. To all that differently different shapes mean different function. This |
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99:03 | where I used to make you guys up but I know we're running out |
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99:05 | time. See, look at the of movements I can make up |
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99:11 | right? Trying to just stay But look what I can do down |
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99:15 | in my hips, right? I different movement. Look at this, |
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99:22 | can rotate but I can't rotate quite well up there. But my |
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99:28 | I can rotate really well. In , I even have more range of |
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99:33 | up in my neck. It's all of the different shapes. The acid |
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99:40 | are unique in that they also have with the transverse process. A facet |
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99:46 | articulation with the rib. All the rib is called the costal |
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99:52 | And so that little uh articulation is the costal facet, all right. |
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100:00 | place where the rib touches, that's it means. All right. So |
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100:04 | will see this in just a But the thoracic um vertebra, how |
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100:11 | thoracic vertebra were there? 7, , 12, how many pairs of |
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100:17 | do you think you got? See it makes it simple because you |
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100:24 | that the ribs are associated with the vertebrae, not any of the |
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100:30 | Sam and the cox. These are weird ones, as I said, |
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100:33 | fused. So you can see here the sam. Um the sarum itself |
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100:37 | five fuse vertebrae, right? You um an articular process that's superior, |
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100:44 | there's no inferior ones because they've been together with the superior one below |
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100:48 | So this is a structure that you up, it looks like one |
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100:51 | Um You have a series of mina you can see here for a and |
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100:56 | and for and for those four Amena blood vessels and nerves to pass |
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101:00 | So they can go on down to legs and finally down here, that's |
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101:04 | cox. So that's the four cocci are fused together. So remember what |
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101:10 | said, you're gonna be fusing bones a long time. Here's an |
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101:13 | One, this fuses around age So right now, a lot of |
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101:17 | is still cartilage for you guys, it's getting close. All right, |
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101:23 | here ever bruised or broken the it's a whole world of suck just |
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101:28 | you know just terrible. One of worst things ever because this ligament is |
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101:34 | to it. Many bones are attached not bones, many muscles are associated |
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101:38 | the ligament. So every movement is pain. If you bruise or, |
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101:42 | break that bone don't do that, fall on your butt. Yeah. |
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101:49 | she went. Yeah. The worst . Uh All right, we're getting |
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101:55 | , I'm just gonna finish up with thoracic cage when we done with the |
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101:59 | skeleton. Ok. So the thoracic is the fancy word for saying the |
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102:03 | and the bones that are associated with ribs. Um I wanna start here |
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102:07 | the stum. All right. So is your sternum. It has three |
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102:11 | to it. Um The purpose of sternum. Notice where it sits, |
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102:14 | sits in the middle of the cavity here. Its job is to protect |
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102:17 | heart, right? Keep things from . It doesn't keep it from being |
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102:23 | though, just trying to keep you . All right, three parts and |
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102:31 | what I have here is I have tie because it kind of looks like |
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102:34 | tie. This portion right here is the manubrium. The manubrium is the |
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102:39 | that articulates with the clavicle as well the rib. It's only showing you |
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102:44 | here that are that articulate again, means a bone touching another bone. |
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102:49 | will point out here that it's not bone to bone. What we have |
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102:52 | we have a series of cartilage in . So um you can see down |
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102:56 | , we're gonna get to some really long cartilage. This region right |
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102:59 | is called the body. It's also called the gladius. All right. |
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103:04 | here's another fun one. What's the ladies, do you guys know the |
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103:08 | really, really long flower with a of flower things? It's about this |
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103:13 | , you know, what it's starts with a G L clad. |
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103:20 | you ever heard that? You Gladiolas are no. Ok. Um |
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103:24 | , I'm asking the guys now, is the, uh the, uh |
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103:28 | guy that fights in the arena? in Rome, ancient Rome gladiator right |
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103:35 | ? Romans are really simple people. name things for what they do. |
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103:38 | are called gladiators because they run around a sword called a Gladius. Gladiola |
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103:46 | because it looks like a sword gladiator it carries a sword. What does |
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103:51 | look like? Looks like a Really? That, that sounds, |
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103:57 | silly. We name things. All . Very bottom part. This is |
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104:00 | zip void process. Remember I said got things that are lasting forever. |
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104:04 | is the one that ossifies around age . It's the little bottom portion of |
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104:09 | tie. All right. This is point for the abdominal muscles. Uh |
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104:13 | ever been sucker punch in the uh process? Yeah, it's a lot |
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104:17 | fun, isn't, it doesn't have be someone throw a ball at you |
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104:23 | . So you lose, you lose the wind. All right. |
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104:27 | Looking at the ribs real quick. Remember they're attached to the thoracic |
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104:32 | So like I said, there is here, you can see the 12th |
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104:35 | down there. The 11th one comes . Notice here we have special |
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104:39 | We, the first seven are called true ribs. They're the real |
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104:44 | The other ones are the fake Well, no. Right. Why |
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104:47 | call them true ribs because they're directly to the sternum. See how this |
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104:53 | goes directly and is attached to it . And then once you get below |
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104:58 | seven, the rest are the false . Number eight, attaches to number |
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105:02 | , number nine, attaches to number . Number 10, attaches to number |
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105:06 | . Ok. So they're not attached to the sternum. And then the |
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105:11 | 2, 11 and 12 are false , but they're even weirder false ribs |
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105:15 | they don't have any cartilage. They . These are the ones when you |
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105:18 | about uh athletes breaking a rib. know, this is usually the one |
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105:23 | they're talking about these floating ribs because not held in place by anything, |
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105:28 | ? This type of cartilage in between called costal cartilage. Basically the rib |
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105:34 | . And I think that's all we here for the ribs. Oh, |
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105:38 | structure. Oh, my goodness. just keeps going. All right. |
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105:43 | are looking at a rib from the of the uh vertebrae. All |
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105:49 | So what we're looking at is this close to the vertebrae, this is |
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105:52 | here near the sternum. All So we're looking through the body here |
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105:56 | to kind of help you see what looking at the long portion of the |
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106:00 | that comes up and around. So gonna come like this, that is |
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106:04 | to as the shaft, the head the portion of the rib that's attached |
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106:09 | the body of the vertebrae. All . And what we're gonna do is |
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106:12 | gonna go from the head down to neck, right? So here's your |
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106:16 | , head to the neck. And the next portion here as it turns |
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106:21 | called the angle. So the angle what allows you to curve out to |
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106:25 | the shaft. So head neck angle and then the point where the angle |
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106:31 | is the point where we're attached to transverse process, right? So that's |
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106:36 | costal facet. This point here on rib is called the tubercle. So |
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106:44 | neck, sorry head, neck, angle and then coming around, that's |
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106:49 | shaft. Ok. Now, this a flat bone and it's a flat |
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106:54 | . Not even though it has this to it, it's flat because if |
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106:58 | take a slice through it and you at it, you're gonna see that |
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107:00 | shaped this way, it's not And then here we can stop because |
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107:07 | moving on to the axial skeleton. my goodness, it just kept going |
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107:11 | forever, didn't it? All So when we come back, we |
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107:18 | start with the axial skeleton, it really fast when we go through the |
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107:23 | go through the aar skeleton because let's , are your arms exactly the |
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107:29 | Yeah. Are your legs exactly the . Yeah. So they're mirrors of |
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107:32 | other. All right. But we went through roughly half the bones of |
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107:37 | body already. You know. So there's 12 ribs but there's actually two |
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107:43 | . So you 48 ribs, so not 48 24 ribs. You guys |
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107:48 | a great day. I will Is tomorrow Thursday? Are we already |
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107:52 | , wow, he goes quick. it be nice if schools like this |
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107:56 | the time? No, you guys a great day. Enjoy your |
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108:01 | Kick butt, learn stuff. If have questions, I'll be |
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